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- W4318261725 abstract "Central giant cell granuloma of the jaw (CGCJ) can be locally aggressive and result in facial and dental deformity. A child with CGCJ was treated surgically and with denosumab with a response but life-threatening toxicity. Imatinib, a tyrosine kinase inhibitor, was prescribed based on clinical similarities between CGCJ and cherubism, for which Imatinib has been effective. Within 2 months, a computed tomographic scan showed significant ossification, which increased over the following 8 months. This case suggests that tyrosine kinase inhibitors may be an effective option, and one with limited toxicity, for CGCJ." @default.
- W4318261725 created "2023-01-28" @default.
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- W4318261725 date "2022-12-19" @default.
- W4318261725 modified "2023-09-29" @default.
- W4318261725 title "Response of Central Giant Cell Granuloma of the Jaw to Imatinib" @default.
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- W4318261725 doi "https://doi.org/10.1097/mph.0000000000002608" @default.
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