Matches in SemOpenAlex for { <https://semopenalex.org/work/W4318262694> ?p ?o ?g. }
- W4318262694 endingPage "452" @default.
- W4318262694 startingPage "444" @default.
- W4318262694 abstract "Heparin-induced thrombocytopenia (HIT) and vaccine-induced immune thrombotic thrombocytopenia (VITT) are rare, iatrogenic immune-mediated conditions with high rates of thrombosis-related morbidity and mortality. HIT is a long-recognized reaction to the administration of the common parenterally administered anticoagulant heparin (or its derivatives), while VITT is a new, distinct syndrome occurring in response to adenovirus-based vaccines against coronavirus disease 2019 and potentially other types of vaccines. A feature of both HIT and VITT is paradoxical thrombosis despite a characteristic low platelet count, mediated by the presence of platelet-activating antibodies to platelet factor 4. Several additional factors have also been suggested to contribute to clot formation in HIT and/or VITT, including monocytes, tissue factor, microparticles, endothelium, the formation of neutrophil extracellular traps, complement, procoagulant platelets, and vaccine components. In this review, we discuss the literature to date regarding mechanisms contributing to thrombosis in both HIT and VITT and explore the pathophysiological similarities and differences between the two conditions." @default.
- W4318262694 created "2023-01-28" @default.
- W4318262694 creator A5030789412 @default.
- W4318262694 creator A5075581552 @default.
- W4318262694 creator A5091005408 @default.
- W4318262694 date "2023-01-27" @default.
- W4318262694 modified "2023-10-16" @default.
- W4318262694 title "Mechanisms of Thrombosis in Heparin-Induced Thrombocytopenia and Vaccine-Induced Immune Thrombotic Thrombocytopenia" @default.
- W4318262694 cites W124032993 @default.
- W4318262694 cites W1873218418 @default.
- W4318262694 cites W1889263859 @default.
- W4318262694 cites W1931277076 @default.
- W4318262694 cites W1961179763 @default.
- W4318262694 cites W1966558092 @default.
- W4318262694 cites W1975322052 @default.
- W4318262694 cites W2005044790 @default.
- W4318262694 cites W2018487385 @default.
- W4318262694 cites W2024305286 @default.
- W4318262694 cites W2025532828 @default.
- W4318262694 cites W2041695826 @default.
- W4318262694 cites W2043292703 @default.
- W4318262694 cites W2047243131 @default.
- W4318262694 cites W2048583883 @default.
- W4318262694 cites W2064070223 @default.
- W4318262694 cites W2070676143 @default.
- W4318262694 cites W2073637661 @default.
- W4318262694 cites W2075423584 @default.
- W4318262694 cites W2079842229 @default.
- W4318262694 cites W2104934425 @default.
- W4318262694 cites W2106373645 @default.
- W4318262694 cites W2111925820 @default.
- W4318262694 cites W2126980246 @default.
- W4318262694 cites W2165313346 @default.
- W4318262694 cites W2316071283 @default.
- W4318262694 cites W2327059767 @default.
- W4318262694 cites W2333983635 @default.
- W4318262694 cites W2336478335 @default.
- W4318262694 cites W2340152965 @default.
- W4318262694 cites W2563949427 @default.
- W4318262694 cites W2588399936 @default.
- W4318262694 cites W2605967338 @default.
- W4318262694 cites W2749355395 @default.
- W4318262694 cites W2758170836 @default.
- W4318262694 cites W2786262376 @default.
- W4318262694 cites W2890257935 @default.
- W4318262694 cites W2902914300 @default.
- W4318262694 cites W2908872367 @default.
- W4318262694 cites W2920903673 @default.
- W4318262694 cites W2923462844 @default.
- W4318262694 cites W2997918118 @default.
- W4318262694 cites W3007614442 @default.
- W4318262694 cites W3140226555 @default.
- W4318262694 cites W3145359886 @default.
- W4318262694 cites W3152102956 @default.
- W4318262694 cites W3154877986 @default.
- W4318262694 cites W3157184104 @default.
- W4318262694 cites W3159191783 @default.
- W4318262694 cites W3161193856 @default.
- W4318262694 cites W3162895293 @default.
- W4318262694 cites W3165074876 @default.
- W4318262694 cites W3169733086 @default.
- W4318262694 cites W3171181611 @default.
- W4318262694 cites W3172144116 @default.
- W4318262694 cites W3173443401 @default.
- W4318262694 cites W3177218481 @default.
- W4318262694 cites W3180418018 @default.
- W4318262694 cites W3183590901 @default.
- W4318262694 cites W3184696594 @default.
- W4318262694 cites W3187516448 @default.
- W4318262694 cites W3190316885 @default.
- W4318262694 cites W3190412180 @default.
- W4318262694 cites W3191921900 @default.
- W4318262694 cites W3193614926 @default.
- W4318262694 cites W3194362591 @default.
- W4318262694 cites W3196565733 @default.
- W4318262694 cites W3203248391 @default.
- W4318262694 cites W3203440084 @default.
- W4318262694 cites W3213016949 @default.
- W4318262694 cites W3215882035 @default.
- W4318262694 cites W3217252669 @default.
- W4318262694 cites W36050078 @default.
- W4318262694 cites W4205856417 @default.
- W4318262694 cites W4210692457 @default.
- W4318262694 cites W4210915581 @default.
- W4318262694 cites W4213197907 @default.
- W4318262694 cites W4220830703 @default.
- W4318262694 cites W4221063366 @default.
- W4318262694 cites W4221103766 @default.
- W4318262694 cites W4224260129 @default.
- W4318262694 cites W4225253150 @default.
- W4318262694 cites W4225334577 @default.
- W4318262694 cites W4226145370 @default.
- W4318262694 cites W4229000850 @default.
- W4318262694 cites W4251818240 @default.
- W4318262694 cites W4280534425 @default.
- W4318262694 cites W4281685008 @default.
- W4318262694 cites W4281703522 @default.
- W4318262694 cites W4282917174 @default.