Matches in SemOpenAlex for { <https://semopenalex.org/work/W4318305534> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W4318305534 endingPage "130883" @default.
- W4318305534 startingPage "130883" @default.
- W4318305534 abstract "The consumption of cytostatics, pharmaceuticals prescribed in chemotherapy, is increasing every year and worldwide, along with the incidence of cancer. The presence and the temporal evolution of cytostatics in wastewaters from a Portuguese hospital center was evaluated through a 9-month sampling campaign, comprising a total of one hundred and twenty-nine samples, collected from May 2019 to February 2020. Eleven cytostatics out of thirteen pharmaceuticals were studied, including flutamide, mycophenolate mofetil and mycophenolic acid, which have never been monitored before. Target analytes were extracted and quantified by solid-phase extraction coupled to liquid-chromatography-tandem mass spectrometry analysis; the method was fully validated. All pharmaceuticals were detected in at least one sample, bicalutamide being the one found with higher frequency (detected in all samples), followed by mycophenolic acid, which was also the compound detected at higher concentrations (up to 5340 ± 211 ng/L). Etoposide, classified as carcinogenic to humans, was detected in 60% of the samples at concentrations up to 142 ± 15 ng/L. The risk from exposure to cytostatics was estimated for aquatic organisms living in receiving bodies. Cyclophosphamide, doxorubicin, etoposide, flutamide, megestrol and mycophenolic acid are suspected to induce risk. Long-term and synergic effects should not be neglected, even for the cytostatics for which no risk was estimated." @default.
- W4318305534 created "2023-01-28" @default.
- W4318305534 creator A5014098630 @default.
- W4318305534 creator A5018060222 @default.
- W4318305534 creator A5020313467 @default.
- W4318305534 creator A5044180200 @default.
- W4318305534 creator A5071692207 @default.
- W4318305534 creator A5085733387 @default.
- W4318305534 date "2023-04-01" @default.
- W4318305534 modified "2023-10-18" @default.
- W4318305534 title "Multi-target analysis of cytostatics in hospital effluents over a 9-month period" @default.
- W4318305534 cites W1981020418 @default.
- W4318305534 cites W1991657490 @default.
- W4318305534 cites W1992408259 @default.
- W4318305534 cites W1992515321 @default.
- W4318305534 cites W1995192043 @default.
- W4318305534 cites W2001967831 @default.
- W4318305534 cites W2006615194 @default.
- W4318305534 cites W2024061146 @default.
- W4318305534 cites W2033933121 @default.
- W4318305534 cites W2048407248 @default.
- W4318305534 cites W2069471620 @default.
- W4318305534 cites W2086698016 @default.
- W4318305534 cites W2091677051 @default.
- W4318305534 cites W2095064127 @default.
- W4318305534 cites W2151192409 @default.
- W4318305534 cites W2198799102 @default.
- W4318305534 cites W2288968369 @default.
- W4318305534 cites W2299270959 @default.
- W4318305534 cites W2544753069 @default.
- W4318305534 cites W2731411041 @default.
- W4318305534 cites W2778369788 @default.
- W4318305534 cites W2982307589 @default.
- W4318305534 cites W3033652597 @default.
- W4318305534 cites W3093254237 @default.
- W4318305534 cites W3109848422 @default.
- W4318305534 cites W4295009515 @default.
- W4318305534 doi "https://doi.org/10.1016/j.jhazmat.2023.130883" @default.
- W4318305534 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36731320" @default.
- W4318305534 hasPublicationYear "2023" @default.
- W4318305534 type Work @default.
- W4318305534 citedByCount "4" @default.
- W4318305534 countsByYear W43183055342023 @default.
- W4318305534 crossrefType "journal-article" @default.
- W4318305534 hasAuthorship W4318305534A5014098630 @default.
- W4318305534 hasAuthorship W4318305534A5018060222 @default.
- W4318305534 hasAuthorship W4318305534A5020313467 @default.
- W4318305534 hasAuthorship W4318305534A5044180200 @default.
- W4318305534 hasAuthorship W4318305534A5071692207 @default.
- W4318305534 hasAuthorship W4318305534A5085733387 @default.
- W4318305534 hasBestOaLocation W43183055341 @default.
- W4318305534 hasConcept C126322002 @default.
- W4318305534 hasConcept C179998833 @default.
- W4318305534 hasConcept C185592680 @default.
- W4318305534 hasConcept C2776694085 @default.
- W4318305534 hasConcept C2778033501 @default.
- W4318305534 hasConcept C2778119113 @default.
- W4318305534 hasConcept C2911091166 @default.
- W4318305534 hasConcept C43617362 @default.
- W4318305534 hasConcept C71924100 @default.
- W4318305534 hasConcept C81426234 @default.
- W4318305534 hasConcept C98274493 @default.
- W4318305534 hasConceptScore W4318305534C126322002 @default.
- W4318305534 hasConceptScore W4318305534C179998833 @default.
- W4318305534 hasConceptScore W4318305534C185592680 @default.
- W4318305534 hasConceptScore W4318305534C2776694085 @default.
- W4318305534 hasConceptScore W4318305534C2778033501 @default.
- W4318305534 hasConceptScore W4318305534C2778119113 @default.
- W4318305534 hasConceptScore W4318305534C2911091166 @default.
- W4318305534 hasConceptScore W4318305534C43617362 @default.
- W4318305534 hasConceptScore W4318305534C71924100 @default.
- W4318305534 hasConceptScore W4318305534C81426234 @default.
- W4318305534 hasConceptScore W4318305534C98274493 @default.
- W4318305534 hasLocation W43183055341 @default.
- W4318305534 hasLocation W43183055342 @default.
- W4318305534 hasLocation W43183055343 @default.
- W4318305534 hasLocation W43183055344 @default.
- W4318305534 hasOpenAccess W4318305534 @default.
- W4318305534 hasPrimaryLocation W43183055341 @default.
- W4318305534 hasRelatedWork W1979301814 @default.
- W4318305534 hasRelatedWork W1996788646 @default.
- W4318305534 hasRelatedWork W2010416599 @default.
- W4318305534 hasRelatedWork W2010529732 @default.
- W4318305534 hasRelatedWork W2032480086 @default.
- W4318305534 hasRelatedWork W2034075761 @default.
- W4318305534 hasRelatedWork W2063048952 @default.
- W4318305534 hasRelatedWork W2082182379 @default.
- W4318305534 hasRelatedWork W2377201366 @default.
- W4318305534 hasRelatedWork W45839313 @default.
- W4318305534 hasVolume "448" @default.
- W4318305534 isParatext "false" @default.
- W4318305534 isRetracted "false" @default.
- W4318305534 workType "article" @default.