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- W4318478799 endingPage "379" @default.
- W4318478799 startingPage "379" @default.
- W4318478799 abstract "The polyvalent bacteriophage fp01, isolated from wastewater in Valparaiso, Chile, was described to have lytic activity across bacterial species, including Escherichia coli and Salmonella enterica serovars. Due to its polyvalent nature, the bacteriophage fp01 has potential applications in the biomedical, food and agricultural industries. Also, fundamental aspects of polyvalent bacteriophage biology are unknown. In this study, we sequenced and described the complete genome of the polyvalent phage fp01 (MH745368.2) using long- (MinION, Nanopore) and short-reads (MiSeq, Illumina) sequencing. The bacteriophage fp01 genome has 109,515 bp, double-stranded DNA with an average G+C content of 39%, and 158 coding sequences (CDSs). Phage fp01 has genes with high similarity to Escherichia coli, Salmonella enterica, and Shigella sp. phages. Phylogenetic analyses indicated that the phage fp01 is a new Tequintavirus fp01 specie. Receptor binding protein gp108 was identified as potentially responsible for fp01 polyvalent characteristics, which binds to conserved amino acid regions of the FhuA receptor of Enterobacteriaceae." @default.
- W4318478799 created "2023-01-30" @default.
- W4318478799 creator A5000174007 @default.
- W4318478799 creator A5030011781 @default.
- W4318478799 creator A5063899825 @default.
- W4318478799 creator A5065077024 @default.
- W4318478799 creator A5067276328 @default.
- W4318478799 creator A5083217611 @default.
- W4318478799 date "2023-01-28" @default.
- W4318478799 modified "2023-10-14" @default.
- W4318478799 title "Comparative Genomics of a Polyvalent Escherichia-Salmonella Phage fp01 and In Silico Analysis of Its Receptor Binding Protein and Conserved Enterobacteriaceae Phage Receptor" @default.
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- W4318478799 doi "https://doi.org/10.3390/v15020379" @default.
- W4318478799 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36851593" @default.
- W4318478799 hasPublicationYear "2023" @default.
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