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- W4318478996 startingPage "265" @default.
- W4318478996 abstract "This study evaluated a combined systemic and topical anti-infective periodontal treatment of 35 adults who had experienced ongoing periodontal breakdown following conventional surgical periodontics. The prescribed anti-infective therapy, based on microbiological testing, consisted of a single course of metronidazole plus ciprofloxacin (23 patients), metronidazole plus amoxicillin/clavulanic acid (10 patients), and metronidazole plus ciprofloxacin followed by metronidazole plus amoxicillin/clavulanic acid (2 patients). In addition, the study patients received 0.1% povidone-iodine subgingival disinfection during non-surgical root debridement and daily patient administered oral irrigation with 0.1% sodium hypochlorite. At 1 and 5 years post-treatment, all study patients showed gains in clinical periodontal attachment with no further attachment loss, and significant decreases in pocket probing depth, bleeding on probing, and subgingival temperature. The greatest disease resolution occurred in patients who at baseline harbored predominantly major periodontal pathogens which post-antibiotics became non-detectable and substituted by non-periodontopathic viridans streptococci. The personalized and minimally invasive anti-infective treatment regimen described here controlled periodontitis disease activity and markedly improved the clinical and microbiological status of the refractory periodontitis patients." @default.
- W4318478996 created "2023-01-30" @default.
- W4318478996 creator A5049460096 @default.
- W4318478996 creator A5074233034 @default.
- W4318478996 date "2023-01-28" @default.
- W4318478996 modified "2023-10-17" @default.
- W4318478996 title "Antimicrobial Chemotherapy for Recalcitrant Severe Human Periodontitis" @default.
- W4318478996 cites W130933772 @default.
- W4318478996 cites W1511929072 @default.
- W4318478996 cites W1591404538 @default.
- W4318478996 cites W168807060 @default.
- W4318478996 cites W1776670747 @default.
- W4318478996 cites W1911307218 @default.
- W4318478996 cites W1942005526 @default.
- W4318478996 cites W1964700796 @default.
- W4318478996 cites W1964817326 @default.
- W4318478996 cites W1965346018 @default.
- W4318478996 cites W1966341412 @default.
- W4318478996 cites W1967351537 @default.
- W4318478996 cites W1974824543 @default.
- W4318478996 cites W1977835348 @default.
- W4318478996 cites W1980359255 @default.
- W4318478996 cites W1981781283 @default.
- W4318478996 cites W1986759003 @default.
- W4318478996 cites W1989644057 @default.
- W4318478996 cites W1989942989 @default.
- W4318478996 cites W1992871895 @default.
- W4318478996 cites W1993812003 @default.
- W4318478996 cites W1994482779 @default.
- W4318478996 cites W1997261658 @default.
- W4318478996 cites W2009356940 @default.
- W4318478996 cites W2010890477 @default.
- W4318478996 cites W2013258386 @default.
- W4318478996 cites W2014631633 @default.
- W4318478996 cites W2015106392 @default.
- W4318478996 cites W2015580954 @default.
- W4318478996 cites W2017274090 @default.
- W4318478996 cites W2021421470 @default.
- W4318478996 cites W2027024056 @default.
- W4318478996 cites W2028226122 @default.
- W4318478996 cites W2029594785 @default.
- W4318478996 cites W2031394369 @default.
- W4318478996 cites W2032664626 @default.
- W4318478996 cites W2033920950 @default.
- W4318478996 cites W2036761085 @default.
- W4318478996 cites W2045557480 @default.
- W4318478996 cites W2050035976 @default.
- W4318478996 cites W2051431875 @default.
- W4318478996 cites W2057523381 @default.
- W4318478996 cites W2058430210 @default.
- W4318478996 cites W2064504081 @default.
- W4318478996 cites W2068587775 @default.
- W4318478996 cites W2072404932 @default.
- W4318478996 cites W2073084834 @default.
- W4318478996 cites W2075786343 @default.
- W4318478996 cites W2076014638 @default.
- W4318478996 cites W2076976609 @default.
- W4318478996 cites W2079883332 @default.
- W4318478996 cites W2082810901 @default.
- W4318478996 cites W2088769800 @default.
- W4318478996 cites W2091794394 @default.
- W4318478996 cites W2105269512 @default.
- W4318478996 cites W2113125516 @default.
- W4318478996 cites W2114173313 @default.
- W4318478996 cites W2115599207 @default.
- W4318478996 cites W2118707760 @default.
- W4318478996 cites W2122096323 @default.
- W4318478996 cites W2124268933 @default.
- W4318478996 cites W2124388296 @default.
- W4318478996 cites W2125255483 @default.
- W4318478996 cites W2132275585 @default.
- W4318478996 cites W2132719829 @default.
- W4318478996 cites W2134594898 @default.
- W4318478996 cites W2135151494 @default.
- W4318478996 cites W2137147504 @default.
- W4318478996 cites W2141075455 @default.
- W4318478996 cites W2141189854 @default.
- W4318478996 cites W2144610619 @default.
- W4318478996 cites W2149898918 @default.
- W4318478996 cites W2151770107 @default.
- W4318478996 cites W2168597384 @default.
- W4318478996 cites W2238646147 @default.
- W4318478996 cites W2258089850 @default.
- W4318478996 cites W2262123673 @default.
- W4318478996 cites W2398431991 @default.
- W4318478996 cites W2402007597 @default.
- W4318478996 cites W2417047721 @default.
- W4318478996 cites W2515059800 @default.
- W4318478996 cites W253460183 @default.
- W4318478996 cites W2596368248 @default.
- W4318478996 cites W2701723414 @default.
- W4318478996 cites W2730741903 @default.
- W4318478996 cites W2801331451 @default.
- W4318478996 cites W2808636390 @default.
- W4318478996 cites W2809048536 @default.
- W4318478996 cites W2809649739 @default.
- W4318478996 cites W2914491472 @default.
- W4318478996 cites W2982494489 @default.