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- W4318481575 abstract "Background: Depression represents one of the major causes of disability worldwide, with an important socioeconomic cost. Although many risk factors have been considered in its pathogenesis, nutrition seems to play a determinant role in its prevention. With regard to individual macronutrients, dietary fats and especially n-3 polyunsaturated fatty acids (n-3 PUFA) are the most studied. However, previous data about other dietary fatty acids, such as n-6 PUFA, are conflicting, and little is known about saturated fatty acids (SFA), especially when considering carbon chain length. Thus, we investigated whether single types and subtypes of dietary fats are related to depressive symptoms in Italian individuals living in the Mediterranean area. Methods: Dietary and socio-demographic data of 1572 individuals were analyzed. Food frequency questionnaires (FFQs) were used to determine the consumption of total dietary fat and each specific class of dietary fat, such as SFA, monounsaturated fatty acid (MUFA), and PUFA. The intake of fatty acids was also assessed according to the carbon-chain length of each single class. The Center for Epidemiologic Studies Depression Scale (CES-D) was used as a screening tool for depressive symptoms. Results: After adjustment for potential confounding factors, a significant inverse association between low/moderate levels of PUFA intake and depressive symptoms (Q2 vs. Q1, odds ratio (OR) = 0.60, 95% CI: 0.44, 0.84) was found. On the other hand, moderate saturated fat consumption was associated with depressive symptoms (Q3 vs. Q1, OR = 1.44, 95% CI: 1.02, 2.04). However, when considering carbon chain length, individuals with a lower to moderate intake of short-chain saturated fatty acids (SCSFA) and medium-chain saturated fatty acids (MCSFA) were less likely to have depressive symptoms (Q3 vs. Q1, OR = 0.48, 95% CI: 0.31, 0.75), while moderate intake of arachidic acid (C20:0) was directly associated with depressive symptoms (Q3 vs. Q1, OR = 1.87, 95% CI: 1.26, 2.77). Among single MUFAs, higher myristoleic acid (C14:1) intake was directly associated with depressive symptoms (Q4 vs. Q1, OR = 1.71, 95% CI: 1.12, 2.61), while moderate intake of erucic acid (C22:1) was associated with lower odds of having depressive symptoms (Q3 vs. Q1, OR = 0.54, 95% CI: 0.33, 0.86). When considering individual PUFAs, individuals with moderate and higher intakes of arachidonic acid (C20:4) were less likely to have depressive symptoms (OR = 0.64, 95% CI: 0.45, 0.91; OR = 0.59, 95% CI: 0.38, 0.91, respectively). Similarly, higher eicosapentaenoic acid (C20:5) intake was inversely associated with depressive symptoms (Q4 vs. Q1, OR = 0.35, 95% CI: 0.12, 0.98), while a significant association for docosahexaenoic acid (C22:6) was retrieved only for low intakes (Q2 vs. Q1, OR = 0.33, 95% CI: 0.12, 0.88). Conclusions: Dietary fat intake may be associated with depressive symptoms, underlying the importance of distinguishing between different fat types. This study confirms the pivotal role of PUFAs and reopens the debate on the role of saturated fatty acids, suggesting plausible effects of moderate intakes of short-chain fatty acids." @default.
- W4318481575 created "2023-01-30" @default.
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- W4318481575 date "2023-01-28" @default.
- W4318481575 modified "2023-09-24" @default.
- W4318481575 title "Dietary Fats and Depressive Symptoms in Italian Adults" @default.
- W4318481575 cites W1531103650 @default.
- W4318481575 cites W1822413103 @default.
- W4318481575 cites W1941055921 @default.
- W4318481575 cites W1948266836 @default.
- W4318481575 cites W1964505086 @default.
- W4318481575 cites W1972180513 @default.
- W4318481575 cites W1979141585 @default.
- W4318481575 cites W1991279927 @default.
- W4318481575 cites W1998055329 @default.
- W4318481575 cites W2003494755 @default.
- W4318481575 cites W2003923199 @default.
- W4318481575 cites W2019419945 @default.
- W4318481575 cites W2026621046 @default.
- W4318481575 cites W2027508239 @default.
- W4318481575 cites W2047790936 @default.
- W4318481575 cites W2050791118 @default.
- W4318481575 cites W2053482696 @default.
- W4318481575 cites W2066857994 @default.
- W4318481575 cites W2068629398 @default.
- W4318481575 cites W2073935929 @default.
- W4318481575 cites W2074283665 @default.
- W4318481575 cites W2074647381 @default.
- W4318481575 cites W2106623141 @default.
- W4318481575 cites W2114912994 @default.
- W4318481575 cites W2121030518 @default.
- W4318481575 cites W2122071420 @default.
- W4318481575 cites W2128014655 @default.
- W4318481575 cites W2154436564 @default.
- W4318481575 cites W2157045078 @default.
- W4318481575 cites W2170304486 @default.
- W4318481575 cites W2171129594 @default.
- W4318481575 cites W2185734644 @default.
- W4318481575 cites W2216345716 @default.
- W4318481575 cites W2252291255 @default.
- W4318481575 cites W2298125421 @default.
- W4318481575 cites W2404883061 @default.
- W4318481575 cites W2465671508 @default.
- W4318481575 cites W2472140274 @default.
- W4318481575 cites W2509111386 @default.
- W4318481575 cites W2560761293 @default.
- W4318481575 cites W2596616464 @default.
- W4318481575 cites W2617348643 @default.
- W4318481575 cites W2744444973 @default.
- W4318481575 cites W2745400272 @default.
- W4318481575 cites W2766185642 @default.
- W4318481575 cites W2770901889 @default.
- W4318481575 cites W2771022510 @default.
- W4318481575 cites W2772317245 @default.
- W4318481575 cites W2775574923 @default.
- W4318481575 cites W2790009637 @default.
- W4318481575 cites W2797781833 @default.
- W4318481575 cites W2802940905 @default.
- W4318481575 cites W2903881924 @default.
- W4318481575 cites W2912654919 @default.
- W4318481575 cites W2912851278 @default.
- W4318481575 cites W2923530534 @default.
- W4318481575 cites W2981855443 @default.
- W4318481575 cites W2991943222 @default.
- W4318481575 cites W2996449733 @default.
- W4318481575 cites W3003431160 @default.
- W4318481575 cites W3003912482 @default.
- W4318481575 cites W3011009338 @default.
- W4318481575 cites W3018002771 @default.
- W4318481575 cites W3092861045 @default.
- W4318481575 cites W3092985650 @default.
- W4318481575 cites W3105524771 @default.
- W4318481575 cites W3157759986 @default.
- W4318481575 cites W3177907905 @default.
- W4318481575 cites W3181277076 @default.
- W4318481575 cites W3200542481 @default.
- W4318481575 cites W3203310594 @default.
- W4318481575 cites W3204234964 @default.
- W4318481575 cites W3211397738 @default.
- W4318481575 cites W408922884 @default.
- W4318481575 cites W4205281679 @default.
- W4318481575 cites W4220747438 @default.
- W4318481575 cites W4225282292 @default.
- W4318481575 cites W4280566521 @default.
- W4318481575 cites W4280593573 @default.
- W4318481575 cites W4280642470 @default.
- W4318481575 cites W4288718745 @default.
- W4318481575 cites W4306398871 @default.
- W4318481575 doi "https://doi.org/10.3390/nu15030675" @default.
- W4318481575 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36771380" @default.