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- W4318483058 abstract "The reptile skin is a barrier against water loss and pathogens and an armor for mechanical damages. The integument of reptiles consists of two main layers: the epidermis and the dermis. The epidermis, the hard cover of the body which has an armor-like role, varies among extant reptiles in terms of structural aspects such as thickness, hardness or the kinds of appendages it constitutes. The reptile epithelial cells of the epidermis (keratinocytes) are composed of two main proteins: intermediate filament keratins (IFKs) and corneous beta proteins (CBPs). The outer horny layer of the epidermis, stratum corneum, is constituted of keratinocytes by means of terminal differentiation or cornification which is a result of the protein interactions where CBPs associate with and coat the initial scaffold of IFKs. Reptiles were able to colonize the terrestrial environment due to the changes in these epidermal structures, which led to various cornified epidermal appendages such as scales and scutes, a beak, claws or setae. Developmental and structural aspects of the epidermal CBPs as well as their shared chromosomal locus (EDC) indicate an ancestral origin that gave rise to the finest armor of reptilians." @default.
- W4318483058 created "2023-01-30" @default.
- W4318483058 creator A5012622291 @default.
- W4318483058 creator A5068258497 @default.
- W4318483058 date "2023-01-28" @default.
- W4318483058 modified "2023-10-05" @default.
- W4318483058 title "The Story of the Finest Armor: Developmental Aspects of Reptile Skin" @default.
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- W4318483058 doi "https://doi.org/10.3390/jdb11010005" @default.
- W4318483058 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36810457" @default.
- W4318483058 hasPublicationYear "2023" @default.
- W4318483058 type Work @default.