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• W4318577102 abstract "In recent work we identified genes that confer the slow-growing and antibiotic-resistant small-colony variant (SCV) form of Staphylococcus aureus, as associated with the amount of capsule the bacteria produce. In this study we isolated a triclosan-resistant SCV (tr-SCV) and demonstrated that it produces significantly less capsule, an effect that appears to be mediated at the transcriptional stage. As with other SCVs, we found that the tr-SCV produces less toxins, and when compared to both a capsule and an Agr mutant we found the tr-SCV to be significantly attenuated in an insect model of infection." @default.
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• W4318577102 date "2023-01-30" @default.
• W4318577102 modified "2023-09-30" @default.
• W4318577102 title "Triclosan-resistant small-colony variants of Staphylococcus aureus produce less capsule, less phenol-soluble modulins, and are attenuated in a Galleria mellonella model of infection" @default.
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• W4318577102 doi "https://doi.org/10.1099/mic.0.001277" @default.
• W4318577102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36748621" @default.
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