Matches in SemOpenAlex for { <https://semopenalex.org/work/W4318755134> ?p ?o ?g. }
- W4318755134 abstract "The high stability of antibodies and their ability to precisely bind to antigens and endogenous immune receptors, as well as their susceptibility to protein engineering, enable antibody-based therapeutics to be widely applied in cancer, inflammation, infection, and other disorders. Nevertheless, the application of traditional antibody-based therapeutics has certain limitations, such as high price, limited permeability, and protein engineering complexity. Recent breakthroughs in cell membrane nanotechnology have deepened the understanding of the critical role of membrane protein receptors in disease treatment, enabling vesicular-antibody-based therapeutics. Here, the concept of vesicular antibodies that are obtained by modifying target antibodies onto cell membranes for biomedical applications is proposed. Given that an antibody is basically a protein, as an extension of this concept, vesicles or membrane-coated nanoparticles that use surface antibodies and protein receptors on cell membranes for biomedical applications as vesicular antibodies are defined. Furthermore, several engineering strategies for vesicular antibodies are summarized and how vesicular antibodies can be used in a variety of situations is highlighted. In addition, current challenges and future prospects of vesicular antibodies are also discussed. It is anticipated this perspective will provide new insights on the development of next-generation antibodies for enhanced therapeutics." @default.
- W4318755134 created "2023-02-02" @default.
- W4318755134 creator A5002330104 @default.
- W4318755134 creator A5018249388 @default.
- W4318755134 creator A5055657540 @default.
- W4318755134 creator A5067756404 @default.
- W4318755134 creator A5070568188 @default.
- W4318755134 creator A5084280956 @default.
- W4318755134 date "2023-01-31" @default.
- W4318755134 modified "2023-10-12" @default.
- W4318755134 title "Vesicular Antibodies: Shedding Light on Antibody Therapeutics with Cell Membrane Nanotechnology" @default.
- W4318755134 cites W1536036835 @default.
- W4318755134 cites W1572583106 @default.
- W4318755134 cites W1966122087 @default.
- W4318755134 cites W1969305630 @default.
- W4318755134 cites W2016950635 @default.
- W4318755134 cites W2029435311 @default.
- W4318755134 cites W2042634738 @default.
- W4318755134 cites W2042699075 @default.
- W4318755134 cites W2051720243 @default.
- W4318755134 cites W2053929414 @default.
- W4318755134 cites W2054396105 @default.
- W4318755134 cites W2102869104 @default.
- W4318755134 cites W2105365201 @default.
- W4318755134 cites W2112245283 @default.
- W4318755134 cites W2120049814 @default.
- W4318755134 cites W2135637759 @default.
- W4318755134 cites W2139303962 @default.
- W4318755134 cites W2140801307 @default.
- W4318755134 cites W2145479354 @default.
- W4318755134 cites W2147126871 @default.
- W4318755134 cites W2225516873 @default.
- W4318755134 cites W2252933569 @default.
- W4318755134 cites W2263759961 @default.
- W4318755134 cites W2292383635 @default.
- W4318755134 cites W2302088846 @default.
- W4318755134 cites W2315918362 @default.
- W4318755134 cites W2399178805 @default.
- W4318755134 cites W2406375428 @default.
- W4318755134 cites W2503597067 @default.
- W4318755134 cites W2528154592 @default.
- W4318755134 cites W2581996160 @default.
- W4318755134 cites W2587680743 @default.
- W4318755134 cites W2588049964 @default.
- W4318755134 cites W2593910260 @default.
- W4318755134 cites W2605512187 @default.
- W4318755134 cites W2736314522 @default.
- W4318755134 cites W2754964600 @default.
- W4318755134 cites W2762411375 @default.
- W4318755134 cites W2765097474 @default.
- W4318755134 cites W2768543737 @default.
- W4318755134 cites W2769295426 @default.
- W4318755134 cites W2774294088 @default.
- W4318755134 cites W2779672697 @default.
- W4318755134 cites W2782167051 @default.
- W4318755134 cites W2788311872 @default.
- W4318755134 cites W2791781448 @default.
- W4318755134 cites W2794683780 @default.
- W4318755134 cites W2799662486 @default.
- W4318755134 cites W2801633596 @default.
- W4318755134 cites W2885017820 @default.
- W4318755134 cites W2885447533 @default.
- W4318755134 cites W2886642335 @default.
- W4318755134 cites W2887399022 @default.
- W4318755134 cites W2888664067 @default.
- W4318755134 cites W2889191136 @default.
- W4318755134 cites W2893380545 @default.
- W4318755134 cites W2897826078 @default.
- W4318755134 cites W2898455283 @default.
- W4318755134 cites W2900540194 @default.
- W4318755134 cites W2904256540 @default.
- W4318755134 cites W2909717641 @default.
- W4318755134 cites W2911288641 @default.
- W4318755134 cites W2916790876 @default.
- W4318755134 cites W2922112736 @default.
- W4318755134 cites W2932509442 @default.
- W4318755134 cites W2938506185 @default.
- W4318755134 cites W2944739618 @default.
- W4318755134 cites W2946569005 @default.
- W4318755134 cites W2948074633 @default.
- W4318755134 cites W2950771738 @default.
- W4318755134 cites W2951920908 @default.
- W4318755134 cites W2963700080 @default.
- W4318755134 cites W2982245165 @default.
- W4318755134 cites W2982319722 @default.
- W4318755134 cites W2983988502 @default.
- W4318755134 cites W2990189735 @default.
- W4318755134 cites W2994094480 @default.
- W4318755134 cites W3003380594 @default.
- W4318755134 cites W3006282290 @default.
- W4318755134 cites W3010232062 @default.
- W4318755134 cites W3022531941 @default.
- W4318755134 cites W3025987322 @default.
- W4318755134 cites W3028225604 @default.
- W4318755134 cites W3031854953 @default.
- W4318755134 cites W3032478635 @default.
- W4318755134 cites W3034698027 @default.
- W4318755134 cites W3035463957 @default.
- W4318755134 cites W3035752162 @default.
- W4318755134 cites W3036248212 @default.