Matches in SemOpenAlex for { <https://semopenalex.org/work/W4318817812> ?p ?o ?g. }
- W4318817812 endingPage "20" @default.
- W4318817812 startingPage "7" @default.
- W4318817812 abstract "Background: Quantifying ten-year cardiovascular risk can be challenging. Different online risk calculators provide different risk estimates and online risk calculators use only one point in time. However, risk factors occur over the lifetime of the individual. Purpose: This manuscript provides three solutions to improving ten-year cardiovascular risk assessment in individuals at intermediate risk. Methods: Measuring Lipoprotein(a)—Lp(a) is recommended for assessing cardiovascular risk in all individuals who are in the intermediate risk category by standard online risk calculators. Lp(a) is primarily determined by genetic inheritance. It has the undesirable properties of being proatherosclerotic, proinflammatory, and prothrombotic. Measuring apolipoprotein B (apo B) provides a good index of the number of atherosclerotic particles present. Studies have demonstrated that small, dense LDL cholesterol particles are more atherogenic than larger, less dense LDL cholesterol particles. Measuring high sensitivity C-reactive protein (hsCRP) provides a good estimation of the degree of inflammation in the vascular system. Inflammation is a critical component of heart attacks and strokes. It is increased in diabetes and obesity. Treatment to reduce inflammation results in a reduction of cardiovascular events, independent of lipid values. Results: The above three risk factors should be measured in all patients with an intermediate risk score. Routine assays are readily available at a reasonable cost. They are independent risk factors for cardiovascular disease. Their recommendation is based on the pathophysiology of atherosclerotic cardiovascular disease. Successful therapy will result in the decrease of each of these risk factors. Conclusion: The recommended approach will improve the assessment of cardiovascular risk and guide the physician and patient to the correct treatment recommendations." @default.
- W4318817812 created "2023-02-02" @default.
- W4318817812 creator A5004242956 @default.
- W4318817812 creator A5046180945 @default.
- W4318817812 creator A5048645917 @default.
- W4318817812 creator A5054018883 @default.
- W4318817812 creator A5068995341 @default.
- W4318817812 date "2023-01-01" @default.
- W4318817812 modified "2023-10-16" @default.
- W4318817812 title "Improving Cardiovascular Risk Assessment to Optimize Therapy" @default.
- W4318817812 cites W1549919702 @default.
- W4318817812 cites W1856460279 @default.
- W4318817812 cites W1967651329 @default.
- W4318817812 cites W1975968199 @default.
- W4318817812 cites W1975979383 @default.
- W4318817812 cites W1988933958 @default.
- W4318817812 cites W2009191878 @default.
- W4318817812 cites W2033554531 @default.
- W4318817812 cites W2046446693 @default.
- W4318817812 cites W2064043401 @default.
- W4318817812 cites W2066963386 @default.
- W4318817812 cites W2067593712 @default.
- W4318817812 cites W2070820990 @default.
- W4318817812 cites W2090796532 @default.
- W4318817812 cites W2093664978 @default.
- W4318817812 cites W2098657147 @default.
- W4318817812 cites W2104355263 @default.
- W4318817812 cites W2136837197 @default.
- W4318817812 cites W2165605025 @default.
- W4318817812 cites W2235916715 @default.
- W4318817812 cites W2236488484 @default.
- W4318817812 cites W2401782407 @default.
- W4318817812 cites W2533997569 @default.
- W4318817812 cites W2586892149 @default.
- W4318817812 cites W2587775213 @default.
- W4318817812 cites W2597314559 @default.
- W4318817812 cites W2611589877 @default.
- W4318817812 cites W2748400555 @default.
- W4318817812 cites W2945006463 @default.
- W4318817812 cites W2986700515 @default.
- W4318817812 cites W3000712048 @default.
- W4318817812 cites W3003956143 @default.
- W4318817812 cites W3006057482 @default.
- W4318817812 cites W3012265841 @default.
- W4318817812 cites W3091147157 @default.
- W4318817812 cites W3167308685 @default.
- W4318817812 cites W3213895219 @default.
- W4318817812 cites W4210347219 @default.
- W4318817812 cites W4232045253 @default.
- W4318817812 cites W4308258594 @default.
- W4318817812 cites W4308373292 @default.
- W4318817812 doi "https://doi.org/10.4236/wjcd.2023.131002" @default.
- W4318817812 hasPublicationYear "2023" @default.
- W4318817812 type Work @default.
- W4318817812 citedByCount "1" @default.
- W4318817812 countsByYear W43188178122023 @default.
- W4318817812 crossrefType "journal-article" @default.
- W4318817812 hasAuthorship W4318817812A5004242956 @default.
- W4318817812 hasAuthorship W4318817812A5046180945 @default.
- W4318817812 hasAuthorship W4318817812A5048645917 @default.
- W4318817812 hasAuthorship W4318817812A5054018883 @default.
- W4318817812 hasAuthorship W4318817812A5068995341 @default.
- W4318817812 hasBestOaLocation W43188178121 @default.
- W4318817812 hasConcept C12174686 @default.
- W4318817812 hasConcept C126322002 @default.
- W4318817812 hasConcept C134018914 @default.
- W4318817812 hasConcept C152163801 @default.
- W4318817812 hasConcept C177713679 @default.
- W4318817812 hasConcept C2776914184 @default.
- W4318817812 hasConcept C2778163477 @default.
- W4318817812 hasConcept C2779134260 @default.
- W4318817812 hasConcept C2909478654 @default.
- W4318817812 hasConcept C38652104 @default.
- W4318817812 hasConcept C41008148 @default.
- W4318817812 hasConcept C511355011 @default.
- W4318817812 hasConcept C555293320 @default.
- W4318817812 hasConcept C62746215 @default.
- W4318817812 hasConcept C71924100 @default.
- W4318817812 hasConceptScore W4318817812C12174686 @default.
- W4318817812 hasConceptScore W4318817812C126322002 @default.
- W4318817812 hasConceptScore W4318817812C134018914 @default.
- W4318817812 hasConceptScore W4318817812C152163801 @default.
- W4318817812 hasConceptScore W4318817812C177713679 @default.
- W4318817812 hasConceptScore W4318817812C2776914184 @default.
- W4318817812 hasConceptScore W4318817812C2778163477 @default.
- W4318817812 hasConceptScore W4318817812C2779134260 @default.
- W4318817812 hasConceptScore W4318817812C2909478654 @default.
- W4318817812 hasConceptScore W4318817812C38652104 @default.
- W4318817812 hasConceptScore W4318817812C41008148 @default.
- W4318817812 hasConceptScore W4318817812C511355011 @default.
- W4318817812 hasConceptScore W4318817812C555293320 @default.
- W4318817812 hasConceptScore W4318817812C62746215 @default.
- W4318817812 hasConceptScore W4318817812C71924100 @default.
- W4318817812 hasIssue "01" @default.
- W4318817812 hasLocation W43188178121 @default.
- W4318817812 hasOpenAccess W4318817812 @default.
- W4318817812 hasPrimaryLocation W43188178121 @default.
- W4318817812 hasRelatedWork W1976144721 @default.