FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4318967524> ?p ?o ?g. }

• W4318967524 abstract "The present study was aimed at identifying a new magnetic resonance enterography (MRE) parameter assessing the clinical outcome of biological therapy in patients with active ileal/ileocolonic Crohn's disease (CD).Transmural healing (TH) has been associated with improved outcomes in CD. However, some patients with clinical remission and inactive disease at endoscopy do not achieve TH.Ileal/ileocolonic CD patients scheduled for biological therapy were prospectively evaluated, at baseline (T0) and after 1 year of treatment (T1), with Harvey Bradshaw Index score, blood tests, ileocolonscopy, and MRE. Clinical activity was assessed after 2 years of treatment (T2). Wall thickness ratio (WTR) was calculated in the same affected ileal segment, as the ratio between the ileum wall thickness value at T1 and the ileum wall thickness value at T0.A total of 103 patients were included. Mean WTR at T1 in nonresponders was significantly higher than in responders. At receiver operating characteristic analysis, WTR values were significantly associated to biological therapy responsiveness. A WTR cutoff value of 0.77 mm was identified to discriminate responders from nonresponders (sensitivity: 79%; specificity: 67%). In responders, the proportion of patients with a WTR<0.77 was significantly higher than the proportion of patients achieving TH at T1. Among patients achieving endoscopic remission, 11/29 (37.9%) presented TH, while 20/29 (68.9%) presented WTR<0.77 (P: 0.035). At multivariate logistic regression analysis, WTR<0.77 was significantly associated to biological therapy response.WTR index represents an easy-to-calculate MRE parameter and seems to be a promising tool for monitoring therapeutic response in CD patients during biological therapy." @default.
• W4318967524 created "2023-02-03" @default.
• W4318967524 creator A5015345512 @default.
• W4318967524 creator A5034569772 @default.
• W4318967524 creator A5037134872 @default.
• W4318967524 creator A5072474420 @default.
• W4318967524 creator A5074717064 @default.
• W4318967524 creator A5084096786 @default.
• W4318967524 creator A5085002505 @default.
• W4318967524 date "2022-11-21" @default.
• W4318967524 modified "2023-10-01" @default.
• W4318967524 title "Wall Thickness Ratio—A New Magnetic Resonance Parameter—Is Associated With the Outcome of Biological Therapy in Patients With Ileal and Ileocolonic Crohn’s Disease" @default.
• W4318967524 cites W2000150379 @default.
• W4318967524 cites W2008497900 @default.
• W4318967524 cites W2013238856 @default.
• W4318967524 cites W2020350753 @default.
• W4318967524 cites W2020581972 @default.
• W4318967524 cites W2022661087 @default.
• W4318967524 cites W2029746055 @default.
• W4318967524 cites W2051252224 @default.
• W4318967524 cites W2052496052 @default.
• W4318967524 cites W2063513331 @default.
• W4318967524 cites W2071662837 @default.
• W4318967524 cites W2084673760 @default.
• W4318967524 cites W2095164057 @default.
• W4318967524 cites W2102013054 @default.
• W4318967524 cites W2129472148 @default.
• W4318967524 cites W2129558176 @default.
• W4318967524 cites W2129859455 @default.
• W4318967524 cites W2136666308 @default.
• W4318967524 cites W2140741976 @default.
• W4318967524 cites W2145436896 @default.
• W4318967524 cites W2152381563 @default.
• W4318967524 cites W2160269081 @default.
• W4318967524 cites W2171580759 @default.
• W4318967524 cites W2177407638 @default.
• W4318967524 cites W2374675741 @default.
• W4318967524 cites W2509528771 @default.
• W4318967524 cites W2517773231 @default.
• W4318967524 cites W2536623666 @default.
• W4318967524 cites W2593398029 @default.
• W4318967524 cites W2613173051 @default.
• W4318967524 cites W2753269233 @default.
• W4318967524 cites W2784262185 @default.
• W4318967524 cites W2785800471 @default.
• W4318967524 cites W2789641974 @default.
• W4318967524 cites W2790232685 @default.
• W4318967524 cites W2794792041 @default.
• W4318967524 cites W2808694571 @default.
• W4318967524 cites W2888061430 @default.
• W4318967524 cites W2922514589 @default.
• W4318967524 cites W3002744655 @default.
• W4318967524 cites W3013860885 @default.
• W4318967524 cites W3033326247 @default.
• W4318967524 cites W3034911923 @default.
• W4318967524 cites W3137436626 @default.
• W4318967524 cites W3156991610 @default.
• W4318967524 cites W4210922691 @default.
• W4318967524 cites W2986241145 @default.
• W4318967524 doi "https://doi.org/10.1097/mcg.0000000000001809" @default.
• W4318967524 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36730458" @default.
• W4318967524 hasPublicationYear "2022" @default.
• W4318967524 type Work @default.
• W4318967524 citedByCount "0" @default.
• W4318967524 crossrefType "journal-article" @default.
• W4318967524 hasAuthorship W4318967524A5015345512 @default.
• W4318967524 hasAuthorship W4318967524A5034569772 @default.
• W4318967524 hasAuthorship W4318967524A5037134872 @default.
• W4318967524 hasAuthorship W4318967524A5072474420 @default.
• W4318967524 hasAuthorship W4318967524A5074717064 @default.
• W4318967524 hasAuthorship W4318967524A5084096786 @default.
• W4318967524 hasAuthorship W4318967524A5085002505 @default.
• W4318967524 hasConcept C121332964 @default.
• W4318967524 hasConcept C126322002 @default.
• W4318967524 hasConcept C126838900 @default.
• W4318967524 hasConcept C143409427 @default.
• W4318967524 hasConcept C151956035 @default.
• W4318967524 hasConcept C156957248 @default.
• W4318967524 hasConcept C2777226302 @default.
• W4318967524 hasConcept C2778217198 @default.
• W4318967524 hasConcept C2778451229 @default.
• W4318967524 hasConcept C2779134260 @default.
• W4318967524 hasConcept C2779280984 @default.
• W4318967524 hasConcept C58471807 @default.
• W4318967524 hasConcept C62520636 @default.
• W4318967524 hasConcept C71924100 @default.
• W4318967524 hasConcept C76318530 @default.
• W4318967524 hasConcept C90924648 @default.
• W4318967524 hasConceptScore W4318967524C121332964 @default.
• W4318967524 hasConceptScore W4318967524C126322002 @default.
• W4318967524 hasConceptScore W4318967524C126838900 @default.
• W4318967524 hasConceptScore W4318967524C143409427 @default.
• W4318967524 hasConceptScore W4318967524C151956035 @default.
• W4318967524 hasConceptScore W4318967524C156957248 @default.
• W4318967524 hasConceptScore W4318967524C2777226302 @default.
• W4318967524 hasConceptScore W4318967524C2778217198 @default.
• W4318967524 hasConceptScore W4318967524C2778451229 @default.
• W4318967524 hasConceptScore W4318967524C2779134260 @default.
• W4318967524 hasConceptScore W4318967524C2779280984 @default.
• W4318967524 hasConceptScore W4318967524C58471807 @default.

• next