Matches in SemOpenAlex for { <https://semopenalex.org/work/W4319006865> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W4319006865 abstract "Introduction: Carotid atherosclerosis is the culprit of stroke and dementia. It has been linked to cognitive impairment in cerebrovascular diseases . A bulk of evidence suggests that carotid interventions improve cognitive functions in appropriately selected patients. We aim to investigate the factors that modulate changes in episodic memory following carotid recanalization procedures. Methods: A total of 170 subjects undergoing carotid revascularization procedures were recruited prospectively. Neuropsychometric testing was performed preoperatively, and at 1-,6-, and 12-month postoperatively. Rey Auditory Verbal Learning Test (RAVLT) was used to assess episodic memory. Changes in RAVLT sum scores at individual time points were compared to the baseline. Linear and logistic regression models were fitted to predict RAVLT sum baseline score, and postop changes at each time point compared to preop, respectively. Univariate and multivariate analyses (after adjusting for risk factors and patient demographics) were performed and variables with p <0.25 were included in the multivariable analysis. Results: At baseline, having a prior stroke, and being older than 80 years of age were independent predictors of a low preop RAVLT sum score (p=0.001 and p=0.001 respectively). Interestingly, a low preop RAVLT sum score is the only independent predictor of post-intervention cognitive improvement at all three time points compared to preop (P<0.01). CEA and Age <80 years predicted short-term improvement at 1 and 6 months postop. Conversely, carotid artery stenting (CAS) is an independent predictor of verbal memory decline at 1-month post-intervention (p=0.039), while being older than 80 years of age predicted the decline at 1-month (p= 0.046) and 6-month (p= 0.043) postoperatively. Conclusion: Younger patients with severe atherosclerotic carotid disease and low baseline episodic memory scores benefit most from carotid intervention, specifically CEA, whereas age ≥80 years predicts poor baseline memory score and worse intervention-related memory change. Further studies with larger sample sizes are necessary to confirm the characteristics of patients with carotid occlusive disease who could benefit from revascularization procedures." @default.
- W4319006865 created "2023-02-03" @default.
- W4319006865 creator A5000743426 @default.
- W4319006865 creator A5014472658 @default.
- W4319006865 creator A5039542145 @default.
- W4319006865 creator A5059971019 @default.
- W4319006865 creator A5081639252 @default.
- W4319006865 creator A5090006928 @default.
- W4319006865 date "2023-02-01" @default.
- W4319006865 modified "2023-09-23" @default.
- W4319006865 title "Abstract WMP78: Predictors Of Memory And Carotid Intervention-related Memory Changes" @default.
- W4319006865 doi "https://doi.org/10.1161/str.54.suppl_1.wmp78" @default.
- W4319006865 hasPublicationYear "2023" @default.
- W4319006865 type Work @default.
- W4319006865 citedByCount "0" @default.
- W4319006865 crossrefType "journal-article" @default.
- W4319006865 hasAuthorship W4319006865A5000743426 @default.
- W4319006865 hasAuthorship W4319006865A5014472658 @default.
- W4319006865 hasAuthorship W4319006865A5039542145 @default.
- W4319006865 hasAuthorship W4319006865A5059971019 @default.
- W4319006865 hasAuthorship W4319006865A5081639252 @default.
- W4319006865 hasAuthorship W4319006865A5090006928 @default.
- W4319006865 hasConcept C118552586 @default.
- W4319006865 hasConcept C126322002 @default.
- W4319006865 hasConcept C127413603 @default.
- W4319006865 hasConcept C144301174 @default.
- W4319006865 hasConcept C151956035 @default.
- W4319006865 hasConcept C164705383 @default.
- W4319006865 hasConcept C169900460 @default.
- W4319006865 hasConcept C2779134260 @default.
- W4319006865 hasConcept C2779483572 @default.
- W4319006865 hasConcept C2780645631 @default.
- W4319006865 hasConcept C2984863031 @default.
- W4319006865 hasConcept C38180746 @default.
- W4319006865 hasConcept C71924100 @default.
- W4319006865 hasConcept C78519656 @default.
- W4319006865 hasConcept C88576662 @default.
- W4319006865 hasConceptScore W4319006865C118552586 @default.
- W4319006865 hasConceptScore W4319006865C126322002 @default.
- W4319006865 hasConceptScore W4319006865C127413603 @default.
- W4319006865 hasConceptScore W4319006865C144301174 @default.
- W4319006865 hasConceptScore W4319006865C151956035 @default.
- W4319006865 hasConceptScore W4319006865C164705383 @default.
- W4319006865 hasConceptScore W4319006865C169900460 @default.
- W4319006865 hasConceptScore W4319006865C2779134260 @default.
- W4319006865 hasConceptScore W4319006865C2779483572 @default.
- W4319006865 hasConceptScore W4319006865C2780645631 @default.
- W4319006865 hasConceptScore W4319006865C2984863031 @default.
- W4319006865 hasConceptScore W4319006865C38180746 @default.
- W4319006865 hasConceptScore W4319006865C71924100 @default.
- W4319006865 hasConceptScore W4319006865C78519656 @default.
- W4319006865 hasConceptScore W4319006865C88576662 @default.
- W4319006865 hasIssue "Suppl_1" @default.
- W4319006865 hasLocation W43190068651 @default.
- W4319006865 hasOpenAccess W4319006865 @default.
- W4319006865 hasPrimaryLocation W43190068651 @default.
- W4319006865 hasRelatedWork W182016951 @default.
- W4319006865 hasRelatedWork W2064114605 @default.
- W4319006865 hasRelatedWork W2070165017 @default.
- W4319006865 hasRelatedWork W2077992747 @default.
- W4319006865 hasRelatedWork W2133941851 @default.
- W4319006865 hasRelatedWork W2561267217 @default.
- W4319006865 hasRelatedWork W2800576852 @default.
- W4319006865 hasRelatedWork W2992906473 @default.
- W4319006865 hasRelatedWork W3202427971 @default.
- W4319006865 hasRelatedWork W4308959407 @default.
- W4319006865 hasVolume "54" @default.
- W4319006865 isParatext "false" @default.
- W4319006865 isRetracted "false" @default.
- W4319006865 workType "article" @default.