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- W4319014115 endingPage "103513" @default.
- W4319014115 startingPage "103513" @default.
- W4319014115 abstract "In mammals, N6-methyladenosine (m6A) is thought to be the most common and conserved mRNA modification. Methyltransferase-like 3 (METTL3) is the primary regulator of m6A methyl-transformed modification. Small molecules targeting METTL3 could be effective therapeutics for many disorders, given that a large body of research has linked METTL3 dysregulation with a variety of diseases and altered physiological states, especially with the growth and initiation of cancer. Here, we systematically reviewed the discovery of small molecules targeting METTL3, as well as their future development, for researchers studying in the field." @default.
- W4319014115 created "2023-02-03" @default.
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- W4319014115 date "2023-04-01" @default.
- W4319014115 modified "2023-09-28" @default.
- W4319014115 title "The development of small molecules targeting methyltransferase-like 3" @default.
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- W4319014115 doi "https://doi.org/10.1016/j.drudis.2023.103513" @default.
- W4319014115 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36736582" @default.
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