FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4319066052> ?p ?o ?g. }

• W4319066052 endingPage "1" @default.
• W4319066052 startingPage "1" @default.
• W4319066052 abstract "Background: Both humans and small animals suffer from similar metabolic and structural diseases that impact the musculoskeletal system; however, instead of studying animal disease in its own right, animals are more often used as models for research into various human ailments, such as osteoporosis. There are few studies indicating that animals may suffer from osteoporosis, which raises the question of why small animals, which we believe to be equally susceptible, receive so little attention. With this research, we hope to draw the attention of researchers to the fact that the examination of animals for this disease is just as important as the examination of humans; human osteoporosis research receives a great deal of attention, while animals and their health are neglected. Aims: We aimed to analyse the bone volume fraction (BV/TV) and thickness of first (L1) and second (L2) lumbar vertebrae samples from five cadavers using histomorphometric analysis. In addition, we aimed to investigate one cadaver using microcomputed tomography (micro-CT) imaging. Methods: The L1 and L2 vertebrae from five dog carcasses were used to evaluate the BV/TV and the trabecular thicknesses. We used precise sampling criteria, and also developed a methodological approach to the study of the vertebrae. Using semi-automated methods, we performed histomorphometric analysis and microcomputed tomography data analysis. Results: We used five dog cadavers in this research. During the histomorphometry study, we observed that the lowest L1 BV/TV ratio was 7.88% and the highest was 23.08%. The L2 vertebrae BV/TV ranged from 11.58 to 23.7%. The L1 and L2 lumbar trabeculae thicknesses were also measured. L1's smallest trabecula was 17.34 microns and its largest was 31.88. The L2 vertebrae trabecula thickness was 18.76 to 30.75 microns. BV/TV and trabecular thickness were positively correlated (and vice versa). The two-tailed P value was less than 0.00001. This difference is statistically significant. After microcomputed tomography analysis, we discovered regions in the vertebral body with low porosity; these cavities are usually filled with connective tissue. The bone tissue in these areas is more vulnerable, meaning fracture risk has increased. Conclusions: Animals should not just be considered as models for osteoporosis in humans, but also as potential patients. A single test, such as histomorphometry, may not be sufficient; more advanced technology, such as microcomputed tomography, is required, since it reveals the pores that make the vertebral column more brittle and susceptible to fracture." @default.
• W4319066052 created "2023-02-04" @default.
• W4319066052 creator A5006102400 @default.
• W4319066052 creator A5067420694 @default.
• W4319066052 creator A5077735190 @default.
• W4319066052 date "2023-01-01" @default.
• W4319066052 modified "2023-09-30" @default.
• W4319066052 title "Histomorphometry and μCT scan analysis of osteoporosis in spayed female dogs" @default.
• W4319066052 cites W1754956540 @default.
• W4319066052 cites W1973054754 @default.
• W4319066052 cites W1976520665 @default.
• W4319066052 cites W1991938395 @default.
• W4319066052 cites W2032107044 @default.
• W4319066052 cites W2034363378 @default.
• W4319066052 cites W2037549765 @default.
• W4319066052 cites W2043117893 @default.
• W4319066052 cites W2046856386 @default.
• W4319066052 cites W2054034227 @default.
• W4319066052 cites W2073489707 @default.
• W4319066052 cites W2078234219 @default.
• W4319066052 cites W2085249737 @default.
• W4319066052 cites W2087378917 @default.
• W4319066052 cites W2096425957 @default.
• W4319066052 cites W2096589961 @default.
• W4319066052 cites W2143738932 @default.
• W4319066052 cites W2150475621 @default.
• W4319066052 cites W2160120939 @default.
• W4319066052 cites W2173053672 @default.
• W4319066052 cites W2186715574 @default.
• W4319066052 cites W2579249513 @default.
• W4319066052 cites W2949046462 @default.
• W4319066052 cites W2992594632 @default.
• W4319066052 cites W3008513690 @default.
• W4319066052 cites W3100782008 @default.
• W4319066052 cites W3212927343 @default.
• W4319066052 cites W4225112558 @default.
• W4319066052 cites W4285150386 @default.
• W4319066052 cites W49340284 @default.
• W4319066052 doi "https://doi.org/10.5455/ovj.2023.v13.i1.1" @default.
• W4319066052 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36777442" @default.
• W4319066052 hasPublicationYear "2023" @default.
• W4319066052 type Work @default.
• W4319066052 citedByCount "0" @default.
• W4319066052 crossrefType "journal-article" @default.
• W4319066052 hasAuthorship W4319066052A5006102400 @default.
• W4319066052 hasAuthorship W4319066052A5067420694 @default.
• W4319066052 hasAuthorship W4319066052A5077735190 @default.
• W4319066052 hasBestOaLocation W43190660521 @default.
• W4319066052 hasConcept C105702510 @default.
• W4319066052 hasConcept C142724271 @default.
• W4319066052 hasConcept C2776541429 @default.
• W4319066052 hasConcept C2779835254 @default.
• W4319066052 hasConcept C2909674915 @default.
• W4319066052 hasConcept C3018268312 @default.
• W4319066052 hasConcept C44575665 @default.
• W4319066052 hasConcept C71924100 @default.
• W4319066052 hasConcept C91762617 @default.
• W4319066052 hasConceptScore W4319066052C105702510 @default.
• W4319066052 hasConceptScore W4319066052C142724271 @default.
• W4319066052 hasConceptScore W4319066052C2776541429 @default.
• W4319066052 hasConceptScore W4319066052C2779835254 @default.
• W4319066052 hasConceptScore W4319066052C2909674915 @default.
• W4319066052 hasConceptScore W4319066052C3018268312 @default.
• W4319066052 hasConceptScore W4319066052C44575665 @default.
• W4319066052 hasConceptScore W4319066052C71924100 @default.
• W4319066052 hasConceptScore W4319066052C91762617 @default.
• W4319066052 hasIssue "1" @default.
• W4319066052 hasLocation W43190660521 @default.
• W4319066052 hasLocation W43190660522 @default.
• W4319066052 hasLocation W43190660523 @default.
• W4319066052 hasOpenAccess W4319066052 @default.
• W4319066052 hasPrimaryLocation W43190660521 @default.
• W4319066052 hasRelatedWork W2020210545 @default.
• W4319066052 hasRelatedWork W2100387923 @default.
• W4319066052 hasRelatedWork W2242797095 @default.
• W4319066052 hasRelatedWork W2358904605 @default.
• W4319066052 hasRelatedWork W2365340235 @default.
• W4319066052 hasRelatedWork W2371527935 @default.
• W4319066052 hasRelatedWork W2416349658 @default.
• W4319066052 hasRelatedWork W2754051993 @default.
• W4319066052 hasRelatedWork W2945863908 @default.
• W4319066052 hasRelatedWork W3175397307 @default.
• W4319066052 hasVolume "13" @default.
• W4319066052 isParatext "false" @default.
• W4319066052 isRetracted "false" @default.
• W4319066052 workType "article" @default.