FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4319071746> ?p ?o ?g. }

• W4319071746 endingPage "1321" @default.
• W4319071746 startingPage "1306" @default.
• W4319071746 abstract "Hepatitis D virus (HDV) was first described in 1977 and is dependent on the presence of hepatitis B surface antigen (HBsAg) for its entry into cells and on the human host for replication. Due to the envelopment with the hepatitis B virus (HBV) envelope, early phases of HDV entry resemble HBV infection. Unlike HBV, HDV activates innate immune responses. The global prevalence of HDV is estimated to be about 5% of HBsAg positive individuals. However, recent studies have described a wide range of prevalence between 12 to 72 million individuals. Infection can occur as super-infection or co-infection. The diagnosis of active HDV infection involves screening with anti HDV antibodies followed by quantitative PCR testing for HDV RNA in those who are HBsAg positive. The diagnostic studies have evolved over the years improving the validity and reliability of the tests performed. HDV infection is considered the most severe form of viral hepatitis and the HDV genotype may influence the disease course. There are eight major HDV genotypes with prevalence varying by geographic region. HDV treatment has been challenging as HDV strongly depends on the host cell for replication and provides few, if any viral targets. Better understanding of HDV virology has led to the development of several therapeutic agents currently being studied in different phase II and III clinical trials. There is increasing promise of effective therapies that will ameliorate the course of this devastating disease." @default.
• W4319071746 created "2023-02-04" @default.
• W4319071746 creator A5005121951 @default.
• W4319071746 creator A5021560530 @default.
• W4319071746 creator A5027706816 @default.
• W4319071746 creator A5068960425 @default.
• W4319071746 creator A5090868065 @default.
• W4319071746 date "2023-02-06" @default.
• W4319071746 modified "2023-10-17" @default.
• W4319071746 title "Hepatitis delta: epidemiology to recent advances in therapeutic agents" @default.
• W4319071746 cites W1490981311 @default.
• W4319071746 cites W1495704598 @default.
• W4319071746 cites W1520478258 @default.
• W4319071746 cites W1532220042 @default.
• W4319071746 cites W1572584542 @default.
• W4319071746 cites W1608621108 @default.
• W4319071746 cites W1631028738 @default.
• W4319071746 cites W1678644792 @default.
• W4319071746 cites W1690853634 @default.
• W4319071746 cites W1810525385 @default.
• W4319071746 cites W1855580488 @default.
• W4319071746 cites W1921321055 @default.
• W4319071746 cites W1943386879 @default.
• W4319071746 cites W1946946449 @default.
• W4319071746 cites W1963687802 @default.
• W4319071746 cites W1964252716 @default.
• W4319071746 cites W1965052296 @default.
• W4319071746 cites W1967007934 @default.
• W4319071746 cites W1968671224 @default.
• W4319071746 cites W1970438894 @default.
• W4319071746 cites W1972992218 @default.
• W4319071746 cites W1982848096 @default.
• W4319071746 cites W1984472078 @default.
• W4319071746 cites W1985307483 @default.
• W4319071746 cites W1986827635 @default.
• W4319071746 cites W1986988924 @default.
• W4319071746 cites W1987590686 @default.
• W4319071746 cites W1988048301 @default.
• W4319071746 cites W1997270466 @default.
• W4319071746 cites W1998780724 @default.
• W4319071746 cites W1998961564 @default.
• W4319071746 cites W2002969023 @default.
• W4319071746 cites W2011951516 @default.
• W4319071746 cites W2013659134 @default.
• W4319071746 cites W2018231138 @default.
• W4319071746 cites W2020850806 @default.
• W4319071746 cites W2020963980 @default.
• W4319071746 cites W2027032176 @default.
• W4319071746 cites W2029132988 @default.
• W4319071746 cites W2030447698 @default.
• W4319071746 cites W2035991334 @default.
• W4319071746 cites W2041582786 @default.
• W4319071746 cites W2047829320 @default.
• W4319071746 cites W2052084822 @default.
• W4319071746 cites W2056448307 @default.
• W4319071746 cites W2059341073 @default.
• W4319071746 cites W2059477215 @default.
• W4319071746 cites W2060563877 @default.
• W4319071746 cites W2061594530 @default.
• W4319071746 cites W2062557694 @default.
• W4319071746 cites W2065614359 @default.
• W4319071746 cites W2066747004 @default.
• W4319071746 cites W2071993332 @default.
• W4319071746 cites W2075820772 @default.
• W4319071746 cites W2076085176 @default.
• W4319071746 cites W2080068348 @default.
• W4319071746 cites W2082416470 @default.
• W4319071746 cites W2088606001 @default.
• W4319071746 cites W2090981785 @default.
• W4319071746 cites W2091960939 @default.
• W4319071746 cites W2097426984 @default.
• W4319071746 cites W2103618456 @default.
• W4319071746 cites W2107983386 @default.
• W4319071746 cites W2109935555 @default.
• W4319071746 cites W2119139878 @default.
• W4319071746 cites W2120426460 @default.
• W4319071746 cites W2121232055 @default.
• W4319071746 cites W2123857825 @default.
• W4319071746 cites W2130879777 @default.
• W4319071746 cites W2133202656 @default.
• W4319071746 cites W2135222796 @default.
• W4319071746 cites W2135734424 @default.
• W4319071746 cites W2138165669 @default.
• W4319071746 cites W2139139847 @default.
• W4319071746 cites W2139899138 @default.
• W4319071746 cites W2143732242 @default.
• W4319071746 cites W2146244800 @default.
• W4319071746 cites W2147647823 @default.
• W4319071746 cites W2149782865 @default.
• W4319071746 cites W2158953615 @default.
• W4319071746 cites W2165457619 @default.
• W4319071746 cites W2165999624 @default.
• W4319071746 cites W2166256081 @default.
• W4319071746 cites W2167673078 @default.
• W4319071746 cites W2170960984 @default.
• W4319071746 cites W2172081763 @default.
• W4319071746 cites W2183209570 @default.
• W4319071746 cites W2322192972 @default.

• next