Matches in SemOpenAlex for { <https://semopenalex.org/work/W4319262246> ?p ?o ?g. }
- W4319262246 abstract "An approach to achieving dynamic and reversible decoration of DNA-based scaffolds is demonstrated here. To do this, rationally engineered DNA tiles containing enzyme-responsive strands covalently conjugated to different molecular labels are employed. These strands are designed to be recognized and degraded by specific enzymes (i.e., Ribonuclease H, RNase H, or Uracil DNA Glycosylase, UDG) inducing their spontaneous de-hybridization from the assembled tile and replacement by a new strand conjugated to a different label. Multiple enzyme-responsive strands that specifically respond to different enzymes allow for dynamic, orthogonal, and reversible decoration of the DNA structures. As a proof-of-principle of the strategy, the possibility to orthogonally control the distribution of different labels (i.e., fluorophores and small molecules) on the same scaffold without crosstalk is demonstrated. By doing so, DNA scaffolds that display different antibody recognition patterns are obtained. The approach offers the possibility to control the decoration of higher-order supramolecular assemblies (including origami) with several functional moieties to achieve functional biomaterials with improved adaptability, precision, and sensing capabilities." @default.
- W4319262246 created "2023-02-06" @default.
- W4319262246 creator A5004272855 @default.
- W4319262246 creator A5017680128 @default.
- W4319262246 creator A5018935401 @default.
- W4319262246 creator A5037884650 @default.
- W4319262246 date "2023-03-19" @default.
- W4319262246 modified "2023-10-17" @default.
- W4319262246 title "Dynamic and Reversible Decoration of DNA‐Based Scaffolds" @default.
- W4319262246 cites W1557728494 @default.
- W4319262246 cites W1965560011 @default.
- W4319262246 cites W1976815031 @default.
- W4319262246 cites W1989548144 @default.
- W4319262246 cites W1994486848 @default.
- W4319262246 cites W2010976109 @default.
- W4319262246 cites W2019403558 @default.
- W4319262246 cites W2019733001 @default.
- W4319262246 cites W2025423528 @default.
- W4319262246 cites W2034033759 @default.
- W4319262246 cites W2041261315 @default.
- W4319262246 cites W2129931358 @default.
- W4319262246 cites W2139637208 @default.
- W4319262246 cites W2140898147 @default.
- W4319262246 cites W2141947008 @default.
- W4319262246 cites W2154111088 @default.
- W4319262246 cites W2154459955 @default.
- W4319262246 cites W2297980443 @default.
- W4319262246 cites W2520635238 @default.
- W4319262246 cites W2563114532 @default.
- W4319262246 cites W2588140975 @default.
- W4319262246 cites W2606037183 @default.
- W4319262246 cites W2762211499 @default.
- W4319262246 cites W2766073839 @default.
- W4319262246 cites W2782819019 @default.
- W4319262246 cites W2790708193 @default.
- W4319262246 cites W2793496869 @default.
- W4319262246 cites W2888586602 @default.
- W4319262246 cites W2922847998 @default.
- W4319262246 cites W2939897607 @default.
- W4319262246 cites W2943515348 @default.
- W4319262246 cites W2954935815 @default.
- W4319262246 cites W2963086271 @default.
- W4319262246 cites W2989653485 @default.
- W4319262246 cites W2995670438 @default.
- W4319262246 cites W3008230041 @default.
- W4319262246 cites W3168906023 @default.
- W4319262246 cites W3198179635 @default.
- W4319262246 cites W4200432904 @default.
- W4319262246 cites W4211087439 @default.
- W4319262246 cites W4221089546 @default.
- W4319262246 cites W4224099948 @default.
- W4319262246 cites W4283643718 @default.
- W4319262246 cites W4292365317 @default.
- W4319262246 cites W4306721753 @default.
- W4319262246 cites W4308054136 @default.
- W4319262246 doi "https://doi.org/10.1002/adma.202211274" @default.
- W4319262246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36739507" @default.
- W4319262246 hasPublicationYear "2023" @default.
- W4319262246 type Work @default.
- W4319262246 citedByCount "3" @default.
- W4319262246 countsByYear W43192622462023 @default.
- W4319262246 crossrefType "journal-article" @default.
- W4319262246 hasAuthorship W4319262246A5004272855 @default.
- W4319262246 hasAuthorship W4319262246A5017680128 @default.
- W4319262246 hasAuthorship W4319262246A5018935401 @default.
- W4319262246 hasAuthorship W4319262246A5037884650 @default.
- W4319262246 hasConcept C112613896 @default.
- W4319262246 hasConcept C118630614 @default.
- W4319262246 hasConcept C12554922 @default.
- W4319262246 hasConcept C129275984 @default.
- W4319262246 hasConcept C159985019 @default.
- W4319262246 hasConcept C171250308 @default.
- W4319262246 hasConcept C178790620 @default.
- W4319262246 hasConcept C180577832 @default.
- W4319262246 hasConcept C185592680 @default.
- W4319262246 hasConcept C192562407 @default.
- W4319262246 hasConcept C21951064 @default.
- W4319262246 hasConcept C32909587 @default.
- W4319262246 hasConcept C41008148 @default.
- W4319262246 hasConcept C521977710 @default.
- W4319262246 hasConcept C552990157 @default.
- W4319262246 hasConcept C55493867 @default.
- W4319262246 hasConcept C77088390 @default.
- W4319262246 hasConcept C86803240 @default.
- W4319262246 hasConcept C89429830 @default.
- W4319262246 hasConcept C93275456 @default.
- W4319262246 hasConceptScore W4319262246C112613896 @default.
- W4319262246 hasConceptScore W4319262246C118630614 @default.
- W4319262246 hasConceptScore W4319262246C12554922 @default.
- W4319262246 hasConceptScore W4319262246C129275984 @default.
- W4319262246 hasConceptScore W4319262246C159985019 @default.
- W4319262246 hasConceptScore W4319262246C171250308 @default.
- W4319262246 hasConceptScore W4319262246C178790620 @default.
- W4319262246 hasConceptScore W4319262246C180577832 @default.
- W4319262246 hasConceptScore W4319262246C185592680 @default.
- W4319262246 hasConceptScore W4319262246C192562407 @default.
- W4319262246 hasConceptScore W4319262246C21951064 @default.
- W4319262246 hasConceptScore W4319262246C32909587 @default.
- W4319262246 hasConceptScore W4319262246C41008148 @default.
- W4319262246 hasConceptScore W4319262246C521977710 @default.