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• W4319316982 startingPage "416" @default.
• W4319316982 abstract "Adaptive evolution is a process in which variation that confers an evolutionary advantage in a specific environmental context arises and is propagated through a population. When investigating this process, researchers have mainly focused on describing advantageous phenotypes or putative advantageous genotypes. A recent increase in molecular data accessibility and technological advances has allowed researchers to go beyond description and to make inferences about the mechanisms underlying adaptive evolution. In this systematic review, we discuss articles from 2016 to 2022 that investigated or reviewed the molecular mechanisms underlying adaptive evolution in vertebrates in response to environmental variation. Regulatory elements within the genome and regulatory proteins involved in either gene expression or cellular pathways have been shown to play key roles in adaptive evolution in response to most of the discussed environmental factors. Gene losses were suggested to be associated with an adaptive response in some contexts. Future adaptive evolution research could benefit from more investigations focused on noncoding regions of the genome, gene regulation mechanisms, and gene losses potentially yielding advantageous phenotypes. Investigating how novel advantageous genotypes are conserved could also contribute to our knowledge of adaptive evolution." @default.
• W4319316982 created "2023-02-08" @default.
• W4319316982 creator A5028314157 @default.
• W4319316982 creator A5051724663 @default.
• W4319316982 date "2023-02-05" @default.
• W4319316982 modified "2023-10-18" @default.
• W4319316982 title "Molecular Mechanisms Underlying Vertebrate Adaptive Evolution: A Systematic Review" @default.
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