Matches in SemOpenAlex for { <https://semopenalex.org/work/W4319335987> ?p ?o ?g. }
- W4319335987 endingPage "717" @default.
- W4319335987 startingPage "705" @default.
- W4319335987 abstract "Breast cancer is an important cause of crisis for women's life and health. Voltage-dependent anion channel 1 (VDAC1) is mainly localized in the outer mitochondrial membrane of all eukaryotes, and it plays a crucial role in the cell as the main interface between mitochondria and cellular metabolism. Through bioinformatics, we found that VDAC1 is abnormally highly expressed in breast cancer, and the prognosis of breast cancer patients with high VDAC1 expression is poor. Through in vivo and in vitro experiments, we found that VDAC1 can promote the proliferation, migration and invasion of breast cancer cells. Further research we found that VDAC1 can activate the wnt signaling pathway. Through analysis, we found that miR-874-3p can regulate the expression of VDAC1, and the expression of miR-874-3p is decreased in breast cancer, resulting in the increase of VDAC1 expression. Our findings will provide new targets and ideas for the prevention and treatment of breast cancer." @default.
- W4319335987 created "2023-02-08" @default.
- W4319335987 creator A5000432967 @default.
- W4319335987 creator A5025089526 @default.
- W4319335987 creator A5028282226 @default.
- W4319335987 creator A5039871287 @default.
- W4319335987 creator A5040207561 @default.
- W4319335987 creator A5071074966 @default.
- W4319335987 date "2023-01-10" @default.
- W4319335987 modified "2023-10-09" @default.
- W4319335987 title "miRNA-874-3p inhibits the migration, invasion and proliferation of breast cancer cells by targeting VDAC1" @default.
- W4319335987 cites W1425666771 @default.
- W4319335987 cites W1966451804 @default.
- W4319335987 cites W1979973055 @default.
- W4319335987 cites W1989619850 @default.
- W4319335987 cites W1998477030 @default.
- W4319335987 cites W2008438358 @default.
- W4319335987 cites W2022401741 @default.
- W4319335987 cites W2044386293 @default.
- W4319335987 cites W2098862798 @default.
- W4319335987 cites W2142878546 @default.
- W4319335987 cites W2151282768 @default.
- W4319335987 cites W2269332562 @default.
- W4319335987 cites W2522180657 @default.
- W4319335987 cites W2605610797 @default.
- W4319335987 cites W2624664993 @default.
- W4319335987 cites W2768096340 @default.
- W4319335987 cites W2775396371 @default.
- W4319335987 cites W2790842992 @default.
- W4319335987 cites W2794942839 @default.
- W4319335987 cites W2796949439 @default.
- W4319335987 cites W2810144884 @default.
- W4319335987 cites W2883555173 @default.
- W4319335987 cites W2894698210 @default.
- W4319335987 cites W2900597665 @default.
- W4319335987 cites W2967476178 @default.
- W4319335987 cites W2967901922 @default.
- W4319335987 cites W2970480621 @default.
- W4319335987 cites W2990385663 @default.
- W4319335987 cites W3003160803 @default.
- W4319335987 cites W3020962910 @default.
- W4319335987 cites W3026589626 @default.
- W4319335987 cites W3044903507 @default.
- W4319335987 cites W3082861649 @default.
- W4319335987 cites W3135173891 @default.
- W4319335987 cites W3145684476 @default.
- W4319335987 cites W3158158224 @default.
- W4319335987 cites W3166768260 @default.
- W4319335987 cites W3201787854 @default.
- W4319335987 cites W4211069901 @default.
- W4319335987 cites W4247544731 @default.
- W4319335987 doi "https://doi.org/10.18632/aging.204474" @default.
- W4319335987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36750173" @default.
- W4319335987 hasPublicationYear "2023" @default.
- W4319335987 type Work @default.
- W4319335987 citedByCount "0" @default.
- W4319335987 crossrefType "journal-article" @default.
- W4319335987 hasAuthorship W4319335987A5000432967 @default.
- W4319335987 hasAuthorship W4319335987A5025089526 @default.
- W4319335987 hasAuthorship W4319335987A5028282226 @default.
- W4319335987 hasAuthorship W4319335987A5039871287 @default.
- W4319335987 hasAuthorship W4319335987A5040207561 @default.
- W4319335987 hasAuthorship W4319335987A5071074966 @default.
- W4319335987 hasBestOaLocation W43193359871 @default.
- W4319335987 hasConcept C104317684 @default.
- W4319335987 hasConcept C121608353 @default.
- W4319335987 hasConcept C137620995 @default.
- W4319335987 hasConcept C145059251 @default.
- W4319335987 hasConcept C146587185 @default.
- W4319335987 hasConcept C190283241 @default.
- W4319335987 hasConcept C200784783 @default.
- W4319335987 hasConcept C2779058106 @default.
- W4319335987 hasConcept C502942594 @default.
- W4319335987 hasConcept C530470458 @default.
- W4319335987 hasConcept C54355233 @default.
- W4319335987 hasConcept C547475151 @default.
- W4319335987 hasConcept C55493867 @default.
- W4319335987 hasConcept C62112901 @default.
- W4319335987 hasConcept C62478195 @default.
- W4319335987 hasConcept C86803240 @default.
- W4319335987 hasConcept C95444343 @default.
- W4319335987 hasConceptScore W4319335987C104317684 @default.
- W4319335987 hasConceptScore W4319335987C121608353 @default.
- W4319335987 hasConceptScore W4319335987C137620995 @default.
- W4319335987 hasConceptScore W4319335987C145059251 @default.
- W4319335987 hasConceptScore W4319335987C146587185 @default.
- W4319335987 hasConceptScore W4319335987C190283241 @default.
- W4319335987 hasConceptScore W4319335987C200784783 @default.
- W4319335987 hasConceptScore W4319335987C2779058106 @default.
- W4319335987 hasConceptScore W4319335987C502942594 @default.
- W4319335987 hasConceptScore W4319335987C530470458 @default.
- W4319335987 hasConceptScore W4319335987C54355233 @default.
- W4319335987 hasConceptScore W4319335987C547475151 @default.
- W4319335987 hasConceptScore W4319335987C55493867 @default.
- W4319335987 hasConceptScore W4319335987C62112901 @default.
- W4319335987 hasConceptScore W4319335987C62478195 @default.
- W4319335987 hasConceptScore W4319335987C86803240 @default.
- W4319335987 hasConceptScore W4319335987C95444343 @default.