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- W4319436701 abstract "Background: Supplemental over-the-counter high-dose curcumin preparations are in widespread use for inflammatory conditions. Case summary: We describe a case of a 74-years old male that presented to the emergency department complaining on left thigh pain and spontaneous large hematoma. His medical history was notable for hypertension, diabetes mellitus, hyperlipidemia, atrial fibrillation, ischemic heart disease, status post renal transplantation, and benign prostatic hyperplasia. A week before admission he began taking 1 gram curcumin/day. A diagnosis of left-thigh large hematoma was confirmed by CT scan. Anemia and secondary ischemic changes resolved following packed-red-cells administration but local pain and disability persisted in a follow-up examination, weeks later. In vitro studies have demonstrated inhibition of platelet aggregation by curcumin. In addition, in a rat model, curcumin caused an increase in AUC and Cmax of oral clopidogrel by 1.61 fold and 1.81 fold, respectively." @default.
- W4319436701 created "2023-02-09" @default.
- W4319436701 creator A5091650686 @default.
- W4319436701 date "2022-11-04" @default.
- W4319436701 modified "2023-10-18" @default.
- W4319436701 title "Spontaneous bleeding and curcumin: Case report" @default.
- W4319436701 doi "https://doi.org/10.52768/2766-7820/2141" @default.
- W4319436701 hasPublicationYear "2022" @default.
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