Matches in SemOpenAlex for { <https://semopenalex.org/work/W4319438402> ?p ?o ?g. }
- W4319438402 abstract "The efficacious detection of pathogens and prompt induction of innate immune signaling serve as a crucial component of immune defense against infectious pathogens. Over the past decade, DNA-sensing receptor cyclic GMP-AMP synthase (cGAS) and its downstream signaling adaptor stimulator of interferon genes (STING) have emerged as key mediators of type I interferon (IFN) and nuclear factor-κB (NF-κB) responses in health and infection diseases. Moreover, both cGAS-STING pathway and pathogens have developed delicate strategies to resist each other for their survival. The mechanistic and functional comprehension of the interplay between cGAS-STING pathway and pathogens is opening the way for the development and application of pharmacological agonists and antagonists in the treatment of infectious diseases. Here, we briefly review the current knowledge of DNA sensing through the cGAS-STING pathway, and emphatically highlight the potent undertaking of cGAS-STING signaling pathway in the host against infectious pathogenic organisms." @default.
- W4319438402 created "2023-02-09" @default.
- W4319438402 creator A5003074251 @default.
- W4319438402 creator A5049203208 @default.
- W4319438402 creator A5070717343 @default.
- W4319438402 creator A5070990813 @default.
- W4319438402 creator A5073089482 @default.
- W4319438402 creator A5084482163 @default.
- W4319438402 date "2023-02-06" @default.
- W4319438402 modified "2023-10-17" @default.
- W4319438402 title "Function and regulation of cGAS-STING signaling in infectious diseases" @default.
- W4319438402 cites W1426864743 @default.
- W4319438402 cites W1511398922 @default.
- W4319438402 cites W1559117436 @default.
- W4319438402 cites W1594640193 @default.
- W4319438402 cites W1648719203 @default.
- W4319438402 cites W1667606852 @default.
- W4319438402 cites W177069940 @default.
- W4319438402 cites W1776390480 @default.
- W4319438402 cites W1798681852 @default.
- W4319438402 cites W1878404532 @default.
- W4319438402 cites W1886811890 @default.
- W4319438402 cites W1897605380 @default.
- W4319438402 cites W1907075739 @default.
- W4319438402 cites W1964060538 @default.
- W4319438402 cites W1964271390 @default.
- W4319438402 cites W1968178474 @default.
- W4319438402 cites W1970279912 @default.
- W4319438402 cites W1970741576 @default.
- W4319438402 cites W1971915082 @default.
- W4319438402 cites W1975055427 @default.
- W4319438402 cites W1980923315 @default.
- W4319438402 cites W1984355221 @default.
- W4319438402 cites W1986303112 @default.
- W4319438402 cites W1987350137 @default.
- W4319438402 cites W1995744610 @default.
- W4319438402 cites W2002611996 @default.
- W4319438402 cites W2003034886 @default.
- W4319438402 cites W2004262303 @default.
- W4319438402 cites W2005234042 @default.
- W4319438402 cites W2010839055 @default.
- W4319438402 cites W2016131266 @default.
- W4319438402 cites W2019851585 @default.
- W4319438402 cites W2026134797 @default.
- W4319438402 cites W2031182394 @default.
- W4319438402 cites W2033023829 @default.
- W4319438402 cites W2035232303 @default.
- W4319438402 cites W2041357465 @default.
- W4319438402 cites W2042288276 @default.
- W4319438402 cites W2042433863 @default.
- W4319438402 cites W2042816890 @default.
- W4319438402 cites W2047365750 @default.
- W4319438402 cites W2048992607 @default.
- W4319438402 cites W2051419676 @default.
- W4319438402 cites W2051572323 @default.
- W4319438402 cites W2052681210 @default.
- W4319438402 cites W2053445583 @default.
- W4319438402 cites W2055063197 @default.
- W4319438402 cites W2055991279 @default.
- W4319438402 cites W2057973013 @default.
- W4319438402 cites W2060004514 @default.
- W4319438402 cites W2068965703 @default.
- W4319438402 cites W2069360787 @default.
- W4319438402 cites W2070335304 @default.
- W4319438402 cites W2071267501 @default.
- W4319438402 cites W2072118838 @default.
- W4319438402 cites W2073067684 @default.
- W4319438402 cites W2073132533 @default.
- W4319438402 cites W2077915242 @default.
- W4319438402 cites W2083147016 @default.
- W4319438402 cites W2085162215 @default.
- W4319438402 cites W2085282894 @default.
- W4319438402 cites W2088157683 @default.
- W4319438402 cites W2091144643 @default.
- W4319438402 cites W2093268266 @default.
- W4319438402 cites W2098854209 @default.
- W4319438402 cites W2099610218 @default.
- W4319438402 cites W2100837670 @default.
- W4319438402 cites W2101196984 @default.
- W4319438402 cites W2102564122 @default.
- W4319438402 cites W2110864354 @default.
- W4319438402 cites W2111969980 @default.
- W4319438402 cites W2113757071 @default.
- W4319438402 cites W2116527093 @default.
- W4319438402 cites W2118451644 @default.
- W4319438402 cites W2118537722 @default.
- W4319438402 cites W2119864130 @default.
- W4319438402 cites W2122822209 @default.
- W4319438402 cites W2123645680 @default.
- W4319438402 cites W2124251160 @default.
- W4319438402 cites W2132665880 @default.
- W4319438402 cites W2133972984 @default.
- W4319438402 cites W2134362254 @default.
- W4319438402 cites W2135625883 @default.
- W4319438402 cites W2135783899 @default.
- W4319438402 cites W2136187101 @default.
- W4319438402 cites W2139936109 @default.
- W4319438402 cites W2142433291 @default.
- W4319438402 cites W2145182918 @default.
- W4319438402 cites W2146615611 @default.