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- W4319454498 abstract "Chestnut (Castanea mollissima) shell is rich in flavonoids and our previous studies showed that proanthocyanins and anthocyanins were the two markedly varied flavonoids in chestnut shell extracts (CSE) during digestion. Here, the biotransformation of proanthocyanins and anthocyanins in a simulated gastrointestinal model, and the interactions between non-absorption CSE (NACSE) and gut microbiota in vitro, were investigated by ultra-high-performance liquid chromatography combined with triple-quadrupole mass spectrometry and 16S rRNA sequencing.Chestnut shell was richer in proanthocyanins and anthocyanins, while the loss of proanthocyanins was greater after digestion. Additionally, the content of anthocyanin decreased after gastric digestion but increased after intestinal digestion and remained stable after fermentation. After fermentation, delphinidin-3-O-sambubioside and pelargonidin-3-O-galactoside were newly formed. Furthermore, microbiome profiling indicated that NACSE promoted the proliferation of beneficial bacteria, while inhibiting pathogenic bacteria.All these data suggest that CSE may be a promising candidate to protect gut health. © 2023 Society of Chemical Industry." @default.
- W4319454498 created "2023-02-09" @default.
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- W4319454498 date "2023-02-21" @default.
- W4319454498 modified "2023-10-01" @default.
- W4319454498 title "Proanthocyanins and anthocyanins in chestnut (<i>Castanea mollissima</i>) shell extracts: biotransformation in the simulated gastrointestinal model and interaction with gut microbiota <i>in vitro</i>" @default.
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- W4319454498 doi "https://doi.org/10.1002/jsfa.12480" @default.
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