FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4319460033> ?p ?o ?g. }

• W4319460033 endingPage "105365" @default.
• W4319460033 startingPage "105365" @default.
• W4319460033 abstract "Periplocoside T (PST) from Periploca sepium has insecticidal activity against some lepidopterans, which can significantly inhibit the activity of vacuolar-type H+-ATPases (V-ATPase). V-ATPase is involved in the release of neurotransmitters in vesicles during nerve signal transduction. However, there are actions of PST on behavior and sensory-central nervous system (CNS)-motor neural circuit which are commonly overlooked. After exposure to 500 mg/L PST for 48 h, the difference of the proportion of larvae responding to stimuli in the four Drosophila strains was not significant as compared to controls, but larval mouth hook movement and body wall motion were significantly decreased as compared to controls, and the decrease was more obvious in parats1; DSC1−/− and DSC1−/− strains, especially in parats1; DSC1−/− strain. Compared with control (DMSO), the excitatory junction potential (EJP) frequencies of sensory-CNS-motor circuits in the four Drosophila strains after PST or bafiloymcin A1 (BA1, a V-ATPase specific inhibitor) treatment gradually decreased with time, and the decreasing amplitude of BA1 treatment was greater than that of PST treatment, but both were higher than that of the control. The decay amplitude of EJP frequency in two strains with DSC1 channel knockout was lower than that of w1118 and parats1 strains without DSC1 channel knockout. Thus, the results indicated that PST, similar to BA1, could inhibit the transmission of sensory-CNS-motor circuit excitability of Drosophila larvae by inhibiting the activity of V-ATPase, and DSC1 channel play a role of in regulating the stability of nervous system." @default.
• W4319460033 created "2023-02-09" @default.
• W4319460033 creator A5003105554 @default.
• W4319460033 creator A5005253822 @default.
• W4319460033 creator A5024783713 @default.
• W4319460033 creator A5067597844 @default.
• W4319460033 creator A5071634558 @default.
• W4319460033 date "2023-04-01" @default.
• W4319460033 modified "2023-10-14" @default.
• W4319460033 title "Effects of periplocoside T isolated from Periploca sepium on behavior and sensory-CNS-motor circuits in Drosophila melanogaster larvae" @default.
• W4319460033 cites W1815481768 @default.
• W4319460033 cites W1969764345 @default.
• W4319460033 cites W1975237247 @default.
• W4319460033 cites W2004166741 @default.
• W4319460033 cites W2008968520 @default.
• W4319460033 cites W2016273893 @default.
• W4319460033 cites W2019558825 @default.
• W4319460033 cites W2027358562 @default.
• W4319460033 cites W2036762444 @default.
• W4319460033 cites W2043867460 @default.
• W4319460033 cites W2053154955 @default.
• W4319460033 cites W2062562477 @default.
• W4319460033 cites W2064571984 @default.
• W4319460033 cites W2073506866 @default.
• W4319460033 cites W2080777032 @default.
• W4319460033 cites W2081494131 @default.
• W4319460033 cites W2092284863 @default.
• W4319460033 cites W2108148964 @default.
• W4319460033 cites W2287030368 @default.
• W4319460033 cites W2780331094 @default.
• W4319460033 cites W2801393445 @default.
• W4319460033 cites W2937560073 @default.
• W4319460033 cites W3113319692 @default.
• W4319460033 cites W319219625 @default.
• W4319460033 doi "https://doi.org/10.1016/j.pestbp.2023.105365" @default.
• W4319460033 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36963935" @default.
• W4319460033 hasPublicationYear "2023" @default.
• W4319460033 type Work @default.
• W4319460033 citedByCount "0" @default.
• W4319460033 crossrefType "journal-article" @default.
• W4319460033 hasAuthorship W4319460033A5003105554 @default.
• W4319460033 hasAuthorship W4319460033A5005253822 @default.
• W4319460033 hasAuthorship W4319460033A5024783713 @default.
• W4319460033 hasAuthorship W4319460033A5067597844 @default.
• W4319460033 hasAuthorship W4319460033A5071634558 @default.
• W4319460033 hasConcept C104317684 @default.
• W4319460033 hasConcept C112592302 @default.
• W4319460033 hasConcept C169760540 @default.
• W4319460033 hasConcept C17077164 @default.
• W4319460033 hasConcept C185263204 @default.
• W4319460033 hasConcept C2780104201 @default.
• W4319460033 hasConcept C529278444 @default.
• W4319460033 hasConcept C545706735 @default.
• W4319460033 hasConcept C55493867 @default.
• W4319460033 hasConcept C86803240 @default.
• W4319460033 hasConcept C94487597 @default.
• W4319460033 hasConceptScore W4319460033C104317684 @default.
• W4319460033 hasConceptScore W4319460033C112592302 @default.
• W4319460033 hasConceptScore W4319460033C169760540 @default.
• W4319460033 hasConceptScore W4319460033C17077164 @default.
• W4319460033 hasConceptScore W4319460033C185263204 @default.
• W4319460033 hasConceptScore W4319460033C2780104201 @default.
• W4319460033 hasConceptScore W4319460033C529278444 @default.
• W4319460033 hasConceptScore W4319460033C545706735 @default.
• W4319460033 hasConceptScore W4319460033C55493867 @default.
• W4319460033 hasConceptScore W4319460033C86803240 @default.
• W4319460033 hasConceptScore W4319460033C94487597 @default.
• W4319460033 hasFunder F4320321001 @default.
• W4319460033 hasLocation W43194600331 @default.
• W4319460033 hasLocation W43194600332 @default.
• W4319460033 hasOpenAccess W4319460033 @default.
• W4319460033 hasPrimaryLocation W43194600331 @default.
• W4319460033 hasRelatedWork W1991880126 @default.
• W4319460033 hasRelatedWork W2045706219 @default.
• W4319460033 hasRelatedWork W2079600992 @default.
• W4319460033 hasRelatedWork W2565207404 @default.
• W4319460033 hasRelatedWork W2754932648 @default.
• W4319460033 hasRelatedWork W2911853463 @default.
• W4319460033 hasRelatedWork W3127838298 @default.
• W4319460033 hasRelatedWork W4289782243 @default.
• W4319460033 hasRelatedWork W4365454259 @default.
• W4319460033 hasRelatedWork W4367321619 @default.
• W4319460033 hasVolume "191" @default.
• W4319460033 isParatext "false" @default.
• W4319460033 isRetracted "false" @default.
• W4319460033 workType "article" @default.