Matches in SemOpenAlex for { <https://semopenalex.org/work/W4319460329> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W4319460329 endingPage "355" @default.
- W4319460329 startingPage "349" @default.
- W4319460329 abstract "Abstract Introduction Though the clinical significance of THADA‐IGF2BP3 fusions detected in thyroid nodules preoperatively is still under investigation, the limited literature suggests these lesions are clinically low‐risk. Methods The pathology archives were searched from 2018 to 2022 for all thyroid nodules with a THADA‐IGF2BP3 fusion detected via ThyroSeqV3® analysis. Patient demographics and tumor characteristics were collected. Statistical analyses were performed and p < .05 was considered statistically significant. This study was approved by the institutional review board. Results The case cohort included 34 thyroid nodules with THADA‐IGF2BP3 fusions from 32 patients (average age—56.1 years, range: 30–86, male to female ratio—10:22). The average nodule size was 3.2 cm (range: 1.3–7.3 cm). At the time of biopsy, 21 cases were diagnosed as atypia of undetermined significance/follicular lesion of undetermined significance, 12 as follicular neoplasm/suspicious for follicular neoplasm and 1 as suspicious for malignancy. Surgical resection was performed in 29 patients (13 partial and 16 total thyroidectomies) to give a total of 31 nodules. Papillary thyroid carcinoma was diagnosed in 19/31 (61%) cases. No cases showed extrathyroidal extension or lymphovascular invasion. The remaining cases were considered either a low‐risk neoplasm or benign. Four cases of NIFTP on final surgical pathology harbored concurrent incidental papillary thyroid microcarcinoma. One patient had the THADA‐IGF2BP3 fusion detected in bilateral nodules. Conclusions THADA‐IGF2BP3 fusions can occur in malignant, low‐risk and benign thyroid neoplasms, where malignant neoplasms show lack of aggressive features. Therefore, such entities can be classified as clinically low risk." @default.
- W4319460329 created "2023-02-09" @default.
- W4319460329 creator A5003136882 @default.
- W4319460329 creator A5059413817 @default.
- W4319460329 creator A5063058227 @default.
- W4319460329 date "2023-02-08" @default.
- W4319460329 modified "2023-09-26" @default.
- W4319460329 title "<i>THADA‐IGF2BP3</i> fusions detected in fine‐needle aspiration specimens of thyroid nodules: An institutional experience" @default.
- W4319460329 cites W1484128005 @default.
- W4319460329 cites W1497855464 @default.
- W4319460329 cites W1991173762 @default.
- W4319460329 cites W2010028216 @default.
- W4319460329 cites W2030459046 @default.
- W4319460329 cites W2084403048 @default.
- W4319460329 cites W2091408887 @default.
- W4319460329 cites W2109174925 @default.
- W4319460329 cites W2294752554 @default.
- W4319460329 cites W2337882641 @default.
- W4319460329 cites W2508926319 @default.
- W4319460329 cites W2588294799 @default.
- W4319460329 cites W2617786010 @default.
- W4319460329 cites W2970632710 @default.
- W4319460329 cites W3087299429 @default.
- W4319460329 cites W3091866759 @default.
- W4319460329 cites W3124182471 @default.
- W4319460329 cites W3162980103 @default.
- W4319460329 cites W3194364007 @default.
- W4319460329 cites W4220666025 @default.
- W4319460329 doi "https://doi.org/10.1002/dc.25113" @default.
- W4319460329 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36752652" @default.
- W4319460329 hasPublicationYear "2023" @default.
- W4319460329 type Work @default.
- W4319460329 citedByCount "0" @default.
- W4319460329 crossrefType "journal-article" @default.
- W4319460329 hasAuthorship W4319460329A5003136882 @default.
- W4319460329 hasAuthorship W4319460329A5059413817 @default.
- W4319460329 hasAuthorship W4319460329A5063058227 @default.
- W4319460329 hasConcept C121608353 @default.
- W4319460329 hasConcept C126322002 @default.
- W4319460329 hasConcept C126838900 @default.
- W4319460329 hasConcept C142724271 @default.
- W4319460329 hasConcept C151730666 @default.
- W4319460329 hasConcept C2775934546 @default.
- W4319460329 hasConcept C2776170712 @default.
- W4319460329 hasConcept C2776731575 @default.
- W4319460329 hasConcept C2778740770 @default.
- W4319460329 hasConcept C2779013556 @default.
- W4319460329 hasConcept C2779022025 @default.
- W4319460329 hasConcept C2779399171 @default.
- W4319460329 hasConcept C2779761222 @default.
- W4319460329 hasConcept C2780399592 @default.
- W4319460329 hasConcept C2781283455 @default.
- W4319460329 hasConcept C2993294228 @default.
- W4319460329 hasConcept C526584372 @default.
- W4319460329 hasConcept C71924100 @default.
- W4319460329 hasConcept C86803240 @default.
- W4319460329 hasConceptScore W4319460329C121608353 @default.
- W4319460329 hasConceptScore W4319460329C126322002 @default.
- W4319460329 hasConceptScore W4319460329C126838900 @default.
- W4319460329 hasConceptScore W4319460329C142724271 @default.
- W4319460329 hasConceptScore W4319460329C151730666 @default.
- W4319460329 hasConceptScore W4319460329C2775934546 @default.
- W4319460329 hasConceptScore W4319460329C2776170712 @default.
- W4319460329 hasConceptScore W4319460329C2776731575 @default.
- W4319460329 hasConceptScore W4319460329C2778740770 @default.
- W4319460329 hasConceptScore W4319460329C2779013556 @default.
- W4319460329 hasConceptScore W4319460329C2779022025 @default.
- W4319460329 hasConceptScore W4319460329C2779399171 @default.
- W4319460329 hasConceptScore W4319460329C2779761222 @default.
- W4319460329 hasConceptScore W4319460329C2780399592 @default.
- W4319460329 hasConceptScore W4319460329C2781283455 @default.
- W4319460329 hasConceptScore W4319460329C2993294228 @default.
- W4319460329 hasConceptScore W4319460329C526584372 @default.
- W4319460329 hasConceptScore W4319460329C71924100 @default.
- W4319460329 hasConceptScore W4319460329C86803240 @default.
- W4319460329 hasIssue "6" @default.
- W4319460329 hasLocation W43194603291 @default.
- W4319460329 hasLocation W43194603292 @default.
- W4319460329 hasOpenAccess W4319460329 @default.
- W4319460329 hasPrimaryLocation W43194603291 @default.
- W4319460329 hasRelatedWork W1993750017 @default.
- W4319460329 hasRelatedWork W1997599165 @default.
- W4319460329 hasRelatedWork W2028726180 @default.
- W4319460329 hasRelatedWork W2143285762 @default.
- W4319460329 hasRelatedWork W2157743352 @default.
- W4319460329 hasRelatedWork W2612888612 @default.
- W4319460329 hasRelatedWork W2918500971 @default.
- W4319460329 hasRelatedWork W2958771685 @default.
- W4319460329 hasRelatedWork W3032378677 @default.
- W4319460329 hasRelatedWork W3202703666 @default.
- W4319460329 hasVolume "51" @default.
- W4319460329 isParatext "false" @default.
- W4319460329 isRetracted "false" @default.
- W4319460329 workType "article" @default.