FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4319461085> ?p ?o ?g. }

• W4319461085 endingPage "54" @default.
• W4319461085 startingPage "45" @default.
• W4319461085 abstract "Chemical stimulation of the lateral hypothalamus (LH) induces analgesia by forming neural circuitries with multiple brain regions. The involvement of hippocampal dopaminergic receptors in the LH stimulation-induced antinociception in specific pain models in animals has been documented. However, because the neural circuitries involved in the mediation of orofacial pain are not the same as those that mediate the other types of pain, the present study aims to detect the role of dopamine receptors within the dentate gyrus (DG) in the antinociceptive responses induced by LH stimulation in an animal model of orofacial pain. Male Wistar rats (220-250 g) were implanted with two separate cannulae into the LH and DG on the same side. D1- or D2-like dopamine receptor antagonist, SCH23390, or sulpiride (0.25, 1, and 4 μg) were microinjected into the DG, five minutes before intra-LH injection of carbachol (250 nM). The animals were then injected with formalin 1% (50 μL; sc) into the upper lip lateral to the nose and subjected to the orofacial formalin test. Intra-DG administration of SCH23390 or sulpiride attenuated the antinociceptive responses induced by intra-LH microinjection of carbachol during the orofacial formalin test. The findings of the current study suggest that chemical stimulation of the LH modulates orofacial pain, possibly through activation of the DG dopaminergic neurons. Due to the high incidence and prevalence of orofacial pain in the general population, understanding how such neuronal circuitry modulates nociceptive processing will advance the search for novel therapeutics." @default.
• W4319461085 created "2023-02-09" @default.
• W4319461085 creator A5011327799 @default.
• W4319461085 creator A5012711748 @default.
• W4319461085 creator A5016556859 @default.
• W4319461085 creator A5042725822 @default.
• W4319461085 creator A5053172178 @default.
• W4319461085 creator A5061504639 @default.
• W4319461085 date "2023-01-04" @default.
• W4319461085 modified "2023-10-16" @default.
• W4319461085 title "Involvement of dopaminergic system in the dentate gyrus of the hippocampus in modulating the orofacial pain-related behaviors in the rats" @default.
• W4319461085 cites W1627229807 @default.
• W4319461085 cites W1925492557 @default.
• W4319461085 cites W1964719865 @default.
• W4319461085 cites W1964917696 @default.
• W4319461085 cites W1968168439 @default.
• W4319461085 cites W1968935486 @default.
• W4319461085 cites W1978745843 @default.
• W4319461085 cites W1993697283 @default.
• W4319461085 cites W2004901620 @default.
• W4319461085 cites W2009345240 @default.
• W4319461085 cites W2010995220 @default.
• W4319461085 cites W2016794146 @default.
• W4319461085 cites W2020702858 @default.
• W4319461085 cites W2023471854 @default.
• W4319461085 cites W2028121897 @default.
• W4319461085 cites W2035662131 @default.
• W4319461085 cites W2052497364 @default.
• W4319461085 cites W2075010494 @default.
• W4319461085 cites W2077786916 @default.
• W4319461085 cites W2083979382 @default.
• W4319461085 cites W2097744565 @default.
• W4319461085 cites W2117480181 @default.
• W4319461085 cites W2199812300 @default.
• W4319461085 cites W2513677007 @default.
• W4319461085 cites W2765299763 @default.
• W4319461085 cites W2794426394 @default.
• W4319461085 cites W2883205900 @default.
• W4319461085 cites W2905176374 @default.
• W4319461085 cites W3034931751 @default.
• W4319461085 cites W3091208455 @default.
• W4319461085 cites W3093924088 @default.
• W4319461085 cites W3138410242 @default.
• W4319461085 cites W3164282765 @default.
• W4319461085 cites W3173910768 @default.
• W4319461085 cites W4293542307 @default.
• W4319461085 cites W83735416 @default.
• W4319461085 cites W2955654125 @default.
• W4319461085 cites W3002609266 @default.
• W4319461085 doi "https://doi.org/10.1097/fbp.0000000000000710" @default.
• W4319461085 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36752577" @default.
• W4319461085 hasPublicationYear "2023" @default.
• W4319461085 type Work @default.
• W4319461085 citedByCount "0" @default.
• W4319461085 crossrefType "journal-article" @default.
• W4319461085 hasAuthorship W4319461085A5011327799 @default.
• W4319461085 hasAuthorship W4319461085A5012711748 @default.
• W4319461085 hasAuthorship W4319461085A5016556859 @default.
• W4319461085 hasAuthorship W4319461085A5042725822 @default.
• W4319461085 hasAuthorship W4319461085A5053172178 @default.
• W4319461085 hasAuthorship W4319461085A5061504639 @default.
• W4319461085 hasConcept C120069818 @default.
• W4319461085 hasConcept C126322002 @default.
• W4319461085 hasConcept C126838900 @default.
• W4319461085 hasConcept C134018914 @default.
• W4319461085 hasConcept C137183658 @default.
• W4319461085 hasConcept C148762608 @default.
• W4319461085 hasConcept C15490471 @default.
• W4319461085 hasConcept C15744967 @default.
• W4319461085 hasConcept C169760540 @default.
• W4319461085 hasConcept C170493617 @default.
• W4319461085 hasConcept C24998067 @default.
• W4319461085 hasConcept C2776286997 @default.
• W4319461085 hasConcept C2776464000 @default.
• W4319461085 hasConcept C2781463296 @default.
• W4319461085 hasConcept C513476851 @default.
• W4319461085 hasConcept C71924100 @default.
• W4319461085 hasConceptScore W4319461085C120069818 @default.
• W4319461085 hasConceptScore W4319461085C126322002 @default.
• W4319461085 hasConceptScore W4319461085C126838900 @default.
• W4319461085 hasConceptScore W4319461085C134018914 @default.
• W4319461085 hasConceptScore W4319461085C137183658 @default.
• W4319461085 hasConceptScore W4319461085C148762608 @default.
• W4319461085 hasConceptScore W4319461085C15490471 @default.
• W4319461085 hasConceptScore W4319461085C15744967 @default.
• W4319461085 hasConceptScore W4319461085C169760540 @default.
• W4319461085 hasConceptScore W4319461085C170493617 @default.
• W4319461085 hasConceptScore W4319461085C24998067 @default.
• W4319461085 hasConceptScore W4319461085C2776286997 @default.
• W4319461085 hasConceptScore W4319461085C2776464000 @default.
• W4319461085 hasConceptScore W4319461085C2781463296 @default.
• W4319461085 hasConceptScore W4319461085C513476851 @default.
• W4319461085 hasConceptScore W4319461085C71924100 @default.
• W4319461085 hasIssue "1" @default.
• W4319461085 hasLocation W43194610851 @default.
• W4319461085 hasLocation W43194610852 @default.
• W4319461085 hasOpenAccess W4319461085 @default.
• W4319461085 hasPrimaryLocation W43194610851 @default.

• next