FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4319461946> ?p ?o ?g. }

• W4319461946 endingPage "153" @default.
• W4319461946 startingPage "141" @default.
• W4319461946 abstract "Electronic nicotine delivery system (ENDS) use is maintained by the positive reinforcement associated with preferred flavors. These flavors become conditioned reinforcers through pairings with primary reinforcers. This study sought to extend prior research with intravenous nicotine self-administration and develop a more ecologically valid preclinical model of aerosol self-administration in rats that incorporated flavors paired with sucrose. Rats were first trained to respond for oral sucrose with or without raspberry flavor to establish the flavor as a conditioned reinforcer for some groups. Rats were then exposed to aerosol self-administration. All groups responded for raspberry-flavored aerosol with or without nicotine. Rats responded more for raspberry flavored sucrose than unflavored sucrose. Despite raspberry increasing responding for sucrose, the flavor did not function as a conditioned reinforcer during aerosol self-administration and did not increase responding for nicotine. Throughout the aerosol self-administration phase, most groups responded more on the active than inactive lever, and some groups increased their response when the fixed ratio value was increased. At the end of the study, rats in nicotine groups earned similar or fewer aerosol deliveries than rats in vehicle groups. Aerosolized nicotine did not function as a reinforcer in this study, whereas aerosolized raspberry flavor may have maintained self-administration. Further preclinical investigation is needed to articulate the impact of flavors on ENDS use and whether they offset some aversive effects of nicotine or maintain responding on their own. If flavors reduce some aversive effects of self-administered nicotine, then policies to regulate flavors in e-liquids are prudent." @default.
• W4319461946 created "2023-02-09" @default.
• W4319461946 creator A5023888467 @default.
• W4319461946 creator A5080266916 @default.
• W4319461946 date "2023-01-30" @default.
• W4319461946 modified "2023-09-30" @default.
• W4319461946 title "Development of a nicotine aerosol self-administration model in rats and the effects of e-liquid flavors" @default.
• W4319461946 cites W1032732133 @default.
• W4319461946 cites W155846689 @default.
• W4319461946 cites W179866513 @default.
• W4319461946 cites W1965657664 @default.
• W4319461946 cites W1965721964 @default.
• W4319461946 cites W1966331187 @default.
• W4319461946 cites W1991456213 @default.
• W4319461946 cites W2004634810 @default.
• W4319461946 cites W2008829646 @default.
• W4319461946 cites W2016894965 @default.
• W4319461946 cites W2018033031 @default.
• W4319461946 cites W2021564562 @default.
• W4319461946 cites W2029181754 @default.
• W4319461946 cites W2032000332 @default.
• W4319461946 cites W2045758918 @default.
• W4319461946 cites W2052442783 @default.
• W4319461946 cites W2057801923 @default.
• W4319461946 cites W2059533109 @default.
• W4319461946 cites W2060978384 @default.
• W4319461946 cites W2069587260 @default.
• W4319461946 cites W2072807276 @default.
• W4319461946 cites W2077041350 @default.
• W4319461946 cites W2087432957 @default.
• W4319461946 cites W2098773988 @default.
• W4319461946 cites W2102727405 @default.
• W4319461946 cites W2113102336 @default.
• W4319461946 cites W2115040252 @default.
• W4319461946 cites W2119743323 @default.
• W4319461946 cites W2121945062 @default.
• W4319461946 cites W2129834677 @default.
• W4319461946 cites W2132690415 @default.
• W4319461946 cites W2142542079 @default.
• W4319461946 cites W2146683587 @default.
• W4319461946 cites W2164140396 @default.
• W4319461946 cites W2169637503 @default.
• W4319461946 cites W2325126526 @default.
• W4319461946 cites W2329529242 @default.
• W4319461946 cites W2339469306 @default.
• W4319461946 cites W2342416707 @default.
• W4319461946 cites W2415607850 @default.
• W4319461946 cites W2516346085 @default.
• W4319461946 cites W2555629257 @default.
• W4319461946 cites W2555859912 @default.
• W4319461946 cites W2741648244 @default.
• W4319461946 cites W2767108924 @default.
• W4319461946 cites W2785336116 @default.
• W4319461946 cites W2796522536 @default.
• W4319461946 cites W2805692598 @default.
• W4319461946 cites W2810082463 @default.
• W4319461946 cites W2889369006 @default.
• W4319461946 cites W2891590572 @default.
• W4319461946 cites W2939221881 @default.
• W4319461946 cites W2955162889 @default.
• W4319461946 cites W2967107718 @default.
• W4319461946 cites W2995156809 @default.
• W4319461946 cites W3034797929 @default.
• W4319461946 cites W3047382179 @default.
• W4319461946 cites W3082817511 @default.
• W4319461946 cites W3084389894 @default.
• W4319461946 cites W3130699664 @default.
• W4319461946 cites W3159344668 @default.
• W4319461946 cites W3199241530 @default.
• W4319461946 doi "https://doi.org/10.1097/fbp.0000000000000717" @default.
• W4319461946 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36752651" @default.
• W4319461946 hasPublicationYear "2023" @default.
• W4319461946 type Work @default.
• W4319461946 citedByCount "2" @default.
• W4319461946 countsByYear W43194619462023 @default.
• W4319461946 crossrefType "journal-article" @default.
• W4319461946 hasAuthorship W4319461946A5023888467 @default.
• W4319461946 hasAuthorship W4319461946A5080266916 @default.
• W4319461946 hasConcept C15744967 @default.
• W4319461946 hasConcept C169760540 @default.
• W4319461946 hasConcept C185592680 @default.
• W4319461946 hasConcept C2776954882 @default.
• W4319461946 hasConcept C2778555786 @default.
• W4319461946 hasConcept C2778597767 @default.
• W4319461946 hasConcept C2779547902 @default.
• W4319461946 hasConcept C2780719635 @default.
• W4319461946 hasConcept C31903555 @default.
• W4319461946 hasConcept C42219234 @default.
• W4319461946 hasConcept C67203356 @default.
• W4319461946 hasConcept C71924100 @default.
• W4319461946 hasConcept C77805123 @default.
• W4319461946 hasConcept C82085835 @default.
• W4319461946 hasConcept C98274493 @default.
• W4319461946 hasConceptScore W4319461946C15744967 @default.
• W4319461946 hasConceptScore W4319461946C169760540 @default.
• W4319461946 hasConceptScore W4319461946C185592680 @default.
• W4319461946 hasConceptScore W4319461946C2776954882 @default.
• W4319461946 hasConceptScore W4319461946C2778555786 @default.

• next