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- W4319595162 abstract "Very simple, exact, precise and accurate reversed-phase high-performance liquid chromatography (RP-HPLC) methods used to estimate the amount of fenofibrate in both the bulk and tablet formulations. The reversed-mobile phase buffer and ACN in the proportion (40:60) v/v at a flow rate of 1.0 mL/min were used to create the Princeton (C18) (250 mm x 4.6 mm, 5) column. At 240 nm wavelength, the detection procedure was approved. The RT was established to be 3.905 minutes under fenofibrate’s optimum circumstances. The calibration curve had a range of 87 to 232 g/mL and a correlation coefficient of 0.9994. All-important parameters’ RSD values were below 2.0%. A 99.13 and a 100.44% recovery rate, respectively, were shown to exist. In accordance with ICH requirements, the established technique was evaluated for linearity, specificity, precision, accuracy, and system applicability. The feasibility and repeatability of the suggested technique for determining the amount of the commercially available dosage forms of fenofibrate in tablet and bulk form were also demonstrated." @default.
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- W4319595162 date "2022-12-25" @default.
- W4319595162 modified "2023-09-27" @default.
- W4319595162 title "Development and Validation for the Estimation of Fenofibrate in Pharmaceutical Dosage form by Reversed-phase High-performance Liquid Chromatography" @default.
- W4319595162 doi "https://doi.org/10.25258/ijddt.12.4.22" @default.
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