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- W4319601701 abstract "A compact model able to predict the electrical read-out of field-effect biosensors based on two-dimensional (2D) semiconductors is introduced. It comprises the analytical description of the electrostatics including the charge density in the 2D semiconductor, the site-binding modeling of the barrier oxide surface charge, and the Stern layer plus an ion-permeable membrane, all coupled with the carrier transport inside the biosensor and solved by making use of the Donnan potential inside the ion-permeable membrane formed by charged macromolecules. This electrostatics and transport description account for the main surface-related physical and chemical processes that impact the biosensor electrical performance, including the transport along the low-dimensional channel in the diffusive regime, electrolyte screening, and the impact of biological charges. The model is implemented in Verilog-A and can be employed on standard circuit design tools. The theoretical predictions obtained with the model are validated against measurements of a MoS2 field-effect biosensor for streptavidin detection showing excellent agreement in all operation regimes and leading the way for the circuit-level simulation of biosensors based on 2D semiconductors." @default.
- W4319601701 created "2023-02-09" @default.
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- W4319601701 date "2023-02-07" @default.
- W4319601701 modified "2023-10-09" @default.
- W4319601701 title "Compact Modeling of Two-Dimensional Field-Effect Biosensors" @default.
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- W4319601701 doi "https://doi.org/10.3390/s23041840" @default.
- W4319601701 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36850440" @default.
- W4319601701 hasPublicationYear "2023" @default.
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