Matches in SemOpenAlex for { <https://semopenalex.org/work/W4319602605> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4319602605 abstract "Although COVID-19 vaccination is recommended for the patients with chronic liver disease, the clinical outcomes of COVID-19 vaccinated in patients with chronic hepatitis B (CHB) has not been well characterized. The study aimed to explore the safety and specific antibody responses following COVID-19 vaccination among CHB patients.Patients with CHB were included. All patients were vaccinated with two doses of inactivated vaccine (CoronaVac) or three doses of adjuvanted protein subunit vaccine (ZF2001). The adverse events were recorded and neutralizing antibody (NAb) were determined 14 days following the whole-course vaccination.A total of 200 patients with CHB were included. Specific NAb against SARS-CoV-2 were positive in 170 (84.6%) patients. The median (IQR) concentrations of NAb were 16.32 (8.44-34.10) AU/ml. Comparison of immune responses between CoronaVac and ZF2001 vaccines showed no significant differences in neither the concentrations of NAb nor the seropositive rates (84.4 vs. 85.7%). Moreover, we observed lower immunogenicity in older patients and in patients with cirrhosis or underlying comorbidities. The incidences of adverse events were 37 (18.5%) with the most common adverse event as injection side pain [25 (12.5%)], followed by fatigue [15 (7.5%)]. There were no differences in the frequencies of adverse between CoronaVac and ZF2001 (19.3% vs. 17.6%). Almost all of the adverse reactions were mild and self-resolved within a few days after vaccination. Severe adverse events were not observed.COVID-19 vaccines, CoronaVac and ZF2001 had a favorable safety profile and induced efficient immune response in patients with CHB." @default.
- W4319602605 created "2023-02-09" @default.
- W4319602605 creator A5003439018 @default.
- W4319602605 creator A5008543258 @default.
- W4319602605 creator A5025518354 @default.
- W4319602605 creator A5027123674 @default.
- W4319602605 creator A5048252219 @default.
- W4319602605 creator A5048473316 @default.
- W4319602605 creator A5076670524 @default.
- W4319602605 creator A5090366405 @default.
- W4319602605 date "2023-02-08" @default.
- W4319602605 modified "2023-09-26" @default.
- W4319602605 title "Safety and immunogenicity of inactivated COVID-19 vaccine CoronaVac and the RBD-dimer–based COVID-19 vaccine ZF2001 in chronic hepatitis B patients" @default.
- W4319602605 cites W2091600198 @default.
- W4319602605 cites W2974194331 @default.
- W4319602605 cites W3014695022 @default.
- W4319602605 cites W3045671639 @default.
- W4319602605 cites W3048038750 @default.
- W4319602605 cites W3089697169 @default.
- W4319602605 cites W3113862111 @default.
- W4319602605 cites W3126723886 @default.
- W4319602605 cites W3129058318 @default.
- W4319602605 cites W3142647713 @default.
- W4319602605 cites W3154381950 @default.
- W4319602605 cites W3158247426 @default.
- W4319602605 cites W3158339801 @default.
- W4319602605 cites W3165656738 @default.
- W4319602605 cites W3167672146 @default.
- W4319602605 cites W3178010802 @default.
- W4319602605 cites W3195032016 @default.
- W4319602605 cites W3208822418 @default.
- W4319602605 cites W3211671505 @default.
- W4319602605 cites W4207050895 @default.
- W4319602605 cites W4226060569 @default.
- W4319602605 cites W4229038242 @default.
- W4319602605 cites W4289917850 @default.
- W4319602605 cites W4323653041 @default.
- W4319602605 doi "https://doi.org/10.3389/fmed.2023.1078666" @default.
- W4319602605 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36844234" @default.
- W4319602605 hasPublicationYear "2023" @default.
- W4319602605 type Work @default.
- W4319602605 citedByCount "0" @default.
- W4319602605 crossrefType "journal-article" @default.
- W4319602605 hasAuthorship W4319602605A5003439018 @default.
- W4319602605 hasAuthorship W4319602605A5008543258 @default.
- W4319602605 hasAuthorship W4319602605A5025518354 @default.
- W4319602605 hasAuthorship W4319602605A5027123674 @default.
- W4319602605 hasAuthorship W4319602605A5048252219 @default.
- W4319602605 hasAuthorship W4319602605A5048473316 @default.
- W4319602605 hasAuthorship W4319602605A5076670524 @default.
- W4319602605 hasAuthorship W4319602605A5090366405 @default.
- W4319602605 hasBestOaLocation W43196026051 @default.
- W4319602605 hasConcept C126322002 @default.
- W4319602605 hasConcept C159654299 @default.
- W4319602605 hasConcept C197934379 @default.
- W4319602605 hasConcept C203014093 @default.
- W4319602605 hasConcept C22070199 @default.
- W4319602605 hasConcept C2778616394 @default.
- W4319602605 hasConcept C2780799908 @default.
- W4319602605 hasConcept C2780868878 @default.
- W4319602605 hasConcept C71924100 @default.
- W4319602605 hasConcept C90924648 @default.
- W4319602605 hasConceptScore W4319602605C126322002 @default.
- W4319602605 hasConceptScore W4319602605C159654299 @default.
- W4319602605 hasConceptScore W4319602605C197934379 @default.
- W4319602605 hasConceptScore W4319602605C203014093 @default.
- W4319602605 hasConceptScore W4319602605C22070199 @default.
- W4319602605 hasConceptScore W4319602605C2778616394 @default.
- W4319602605 hasConceptScore W4319602605C2780799908 @default.
- W4319602605 hasConceptScore W4319602605C2780868878 @default.
- W4319602605 hasConceptScore W4319602605C71924100 @default.
- W4319602605 hasConceptScore W4319602605C90924648 @default.
- W4319602605 hasLocation W43196026051 @default.
- W4319602605 hasLocation W43196026052 @default.
- W4319602605 hasLocation W43196026053 @default.
- W4319602605 hasOpenAccess W4319602605 @default.
- W4319602605 hasPrimaryLocation W43196026051 @default.
- W4319602605 hasRelatedWork W1990129756 @default.
- W4319602605 hasRelatedWork W2365878817 @default.
- W4319602605 hasRelatedWork W2381813631 @default.
- W4319602605 hasRelatedWork W3024971576 @default.
- W4319602605 hasRelatedWork W3205282141 @default.
- W4319602605 hasRelatedWork W4214524578 @default.
- W4319602605 hasRelatedWork W4224313992 @default.
- W4319602605 hasRelatedWork W4308302287 @default.
- W4319602605 hasRelatedWork W4361276026 @default.
- W4319602605 hasRelatedWork W4361858380 @default.
- W4319602605 hasVolume "10" @default.
- W4319602605 isParatext "false" @default.
- W4319602605 isRetracted "false" @default.
- W4319602605 workType "article" @default.