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• W4319657002 abstract "A diverse spectrum of benign entities and malignant neoplasms originate from the monotonous mesothelium that lines the serosal membranes of the pleural, pericardial, and peritoneal cavities. The mesothelium of myriad sites shows a common origin from the lateral plate mesoderm; primary mesothelial tumors thus demonstrate similar pathogenesis, imaging findings, and treatment options. Significant changes have been made in the 2021 World Health Organization (WHO) classification schemata of the pleural and pericardial tumors on the basis of recent advances in pathology and genetics. While malignant mesotheliomas are biologically aggressive malignancies that occur primarily in patients exposed to asbestos with attendant poor survival rates, well-differentiated papillary mesothelial tumors and adenomatoid tumors charter a benign clinical course with an excellent prognosis. Mesothelioma in situ is a newly characterized entity represented by recurrent unexplained pleural effusions without any identifiable mass at imaging or thoracoscopy. Immunohistochemical markers based on BAP1, MTAP, CDKN2A, and TRAF7 gene mutations help differentiate diffuse mesotheliomas from benign mesothelial proliferations and localized mesotheliomas. Cross-sectional imaging modalities, including US, CT, MRI, and fluorine 18–fluorodeoxyglucose (FDG) PET/CT, permit diagnosis and play a major role in staging and assessing surgical resectability. Imaging studies are invaluable in providing noninvasive and quantitative assessment of tumor response in patients with unresectable disease. Owing to significant overlap in patient characteristics and pathomorphology, accurate diagnosis based on advanced histopathology techniques and genetic abnormalities is imperative for optimal management and prognostication. While patients with nonepithelioid pleural mesotheliomas benefit from immunotherapy, novel targeted therapies for CDKN2A-, NF2-, and BAP1–altered mesotheliomas are under consideration. © RSNA, 2023 Quiz questions for this article are available through the Online Learning Center." @default.
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• W4319657002 date "2023-03-01" @default.
• W4319657002 modified "2023-10-16" @default.
• W4319657002 title "Mesotheliomas and Benign Mesothelial Tumors: Update on Pathologic and Imaging Findings" @default.
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• W4319657002 cites W1784166192 @default.
• W4319657002 cites W1968447883 @default.
• W4319657002 cites W1977516862 @default.
• W4319657002 cites W1988758132 @default.
• W4319657002 cites W1997241984 @default.
• W4319657002 cites W2025834195 @default.
• W4319657002 cites W2031244439 @default.
• W4319657002 cites W2045203690 @default.
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• W4319657002 cites W2935743672 @default.
• W4319657002 cites W2956223554 @default.
• W4319657002 cites W2964746205 @default.
• W4319657002 cites W2965248944 @default.
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• W4319657002 doi "https://doi.org/10.1148/rg.220128" @default.
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