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- W4319660045 abstract "Lung transplantation is an established treatment of well-selected patients with end-stage respiratory diseases. However, lung transplant recipients have the highest rates of acute and chronic rejection among transplanted solid organs. Owing to ongoing alloimmune recognition and associated immune-driven airway/vascular remodeling, precipitated by multifactorial, endogenous or exogenous, post-transplant injuries to the bronchovascular axis of the secondary pulmonary lobule, most lung transplant recipients will suffer from a pathophysiological decline of their allograft, either functionally and/or structurally. This review discusses current knowledge, barriers, and gaps in acute cellular rejection and chronic lung allograft dysfunction-the greatest impediment to long-term post-transplant survival." @default.
- W4319660045 created "2023-02-10" @default.
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- W4319660045 date "2023-03-01" @default.
- W4319660045 modified "2023-09-30" @default.
- W4319660045 title "Acute Rejection and Chronic Lung Allograft Dysfunction" @default.
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- W4319660045 doi "https://doi.org/10.1016/j.ccm.2022.10.011" @default.
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