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- W4319736145 abstract "Recombinant vaccine which contains immunoprotective antigens such as apical membrane antigen 1 (AMA1) has shown promising prospect in curtailing chicken coccidiosis- a global burden in poultry industry. However, understanding the naturally occurring diversity among these antigens is crucial for vaccine effectiveness. The present study aimed to determine diversity of AMA1 of Eimeria tenella isolates from broiler and free-range chickens in KwaZulu-Natal province of South Africa. Polymerase chain reaction (PCR) amplification of E. tenella AMA1 (EtAMA1) was carried out from both broilers and free-range chicken fecal samples respectively. Sequence analysis revealed low levels of diversity in broiler chickens compared to AMA1 sequences in the free-range chickens. Similarly, haplotype network analysis identified 5 haplotypes to be unique from the existing ones. This study provides baseline information on the diversity of EtAMA1 isolates from chicken farms in KwaZulu-Natal province of South Africa and is crucial to designing effective vaccines." @default.
- W4319736145 created "2023-02-11" @default.
- W4319736145 date "2022-12-31" @default.
- W4319736145 modified "2023-09-30" @default.
- W4319736145 title "595. Genetic diversity of Eimeria tenella apical membrane antigen 1 in chickens from KwaZulu-Natal, South Africa" @default.
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- W4319736145 doi "https://doi.org/10.3920/978-90-8686-940-4_595" @default.
- W4319736145 hasPublicationYear "2022" @default.
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