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- W4319737089 abstract "The genetic integrity of southern African Nguni ecotypes is under potential threat due to both indiscriminate crossbreeding and uncontrolled inbreeding. This study aimed to assess the transboundary genetic diversity and heterozygosity-rich regions of 192 South African (half stud, half research herds) and 96 eSwatini Nguni cattle. A set of 40,930 common single nucleotide polymorphisms (SNPs) were used to study their population structure and runs of heterozygosity (ROHet) profiles. Principal component analysis (PCA) and population structure (K=5) analyses illustrated genomic distinctiveness between South African (SA) and eSwatini (ES) populations, greater admixture for SA research (shared ancestry=0.631±0.353) compared to SA stud (shared ancestry=0.741±0.123), and three subpopulations for ES. The largest proportion (0.650) of the 935 ROHet segments fell within the 0.5-1 Mb length category. Overall, results illustrated that genetic distinctiveness resulted from geographic isolation and production strategies. Although no impending threat to genetic diversity was observed, further loss should be monitored to prevent possible ecotype endangerment." @default.
- W4319737089 created "2023-02-11" @default.
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- W4319737089 date "2022-12-31" @default.
- W4319737089 modified "2023-10-18" @default.
- W4319737089 title "206. Assessing genomic diversity and heterozygosity-rich regions of transboundary Nguni cattle of South Africa and eSwatini" @default.
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- W4319737089 doi "https://doi.org/10.3920/978-90-8686-940-4_206" @default.
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