FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4319787054> ?p ?o ?g. }

• W4319787054 endingPage "370" @default.
• W4319787054 startingPage "369" @default.
• W4319787054 abstract "My name is Bianca B. Batista. I was born in Ribeirão Preto, São Paulo, Brazil. I am currently in the last year of my PhD in the Cellular and Molecular Biology program in the Ribeirão Preto School of Medicine at the University of São Paulo. Employing an unbiased approach, our goal is to identify transcription factors, besides Fur (ferric uptake regulator), involved in iron homeostasis in the environmental opportunistic pathogen Chromobacterium violaceum. I work under the supervision of Prof. José Freire da Silva Neto, an Associate Professor at the University of São Paulo. We identified six possible regulatory systems, besides Fur, involved in iron homeostasis in C. violaceum using transposon mutagenesis and PSA-CAS plates. Notably, deletion of the CV_1057 transcriptional regulator led to an increase in siderophore halos, as well as a decrease in biofilm, violacein, protease, and hemolysin production. Further characterization showed that CV_1057 regulates the expression of vioS, a divergently located gene within the CV_1057 genetic cluster, as seen using RNAseq. Interestingly, the CV_1057 regulon overlapped the CviR regulon, suggesting that CV_1057 might act upstream CviR. Indeed, insertion mutations in cviR and null mutation of cviI (the gene that encodes the production of the autoinducer molecule) and cviR led to an increase in siderophore halos. Genes related to iron homeostasis and those encoding the CPI1 T3SS were regulated by CviR but not CviI, suggesting that CviR can also act without its canonical CviI autoinducer. Our data revealed a complex regulatory cascade involving QS that controls iron homeostasis via siderophore-mediated iron uptake in C. violaceum. My next step after defending my PhD is to apply for a postdoc position. I am certain this is a great opportunity for me to learn new techniques, gather teaching experience, and do networking. Then, I would like to become a professor in a university. Bianca B. Batista, Cellular and Molecular Biology program, Ribeirão Preto School of Medicine, University of São Paulo. E-mail: [email protected] Data sharing not applicable to this article as no datasets were generated or analysed during the current study." @default.
• W4319787054 created "2023-02-11" @default.
• W4319787054 creator A5062153927 @default.
• W4319787054 date "2023-02-21" @default.
• W4319787054 modified "2023-10-03" @default.
• W4319787054 title "Interview with Bianca B. Batista, Molecular Microbiology Poster Award Winner at 2nd Workshop in Microbial Molecular Biology in Campinas, Brazil" @default.
• W4319787054 doi "https://doi.org/10.1111/mmi.15038" @default.
• W4319787054 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36811207" @default.
• W4319787054 hasPublicationYear "2023" @default.
• W4319787054 type Work @default.
• W4319787054 citedByCount "0" @default.
• W4319787054 crossrefType "journal-article" @default.
• W4319787054 hasAuthorship W4319787054A5062153927 @default.
• W4319787054 hasBestOaLocation W43197870541 @default.
• W4319787054 hasConcept C104317684 @default.
• W4319787054 hasConcept C118687296 @default.
• W4319787054 hasConcept C143065580 @default.
• W4319787054 hasConcept C153911025 @default.
• W4319787054 hasConcept C28693550 @default.
• W4319787054 hasConcept C4918238 @default.
• W4319787054 hasConcept C54355233 @default.
• W4319787054 hasConcept C60987743 @default.
• W4319787054 hasConcept C62361671 @default.
• W4319787054 hasConcept C6929976 @default.
• W4319787054 hasConcept C86339819 @default.
• W4319787054 hasConcept C86803240 @default.
• W4319787054 hasConcept C89423630 @default.
• W4319787054 hasConcept C95282255 @default.
• W4319787054 hasConceptScore W4319787054C104317684 @default.
• W4319787054 hasConceptScore W4319787054C118687296 @default.
• W4319787054 hasConceptScore W4319787054C143065580 @default.
• W4319787054 hasConceptScore W4319787054C153911025 @default.
• W4319787054 hasConceptScore W4319787054C28693550 @default.
• W4319787054 hasConceptScore W4319787054C4918238 @default.
• W4319787054 hasConceptScore W4319787054C54355233 @default.
• W4319787054 hasConceptScore W4319787054C60987743 @default.
• W4319787054 hasConceptScore W4319787054C62361671 @default.
• W4319787054 hasConceptScore W4319787054C6929976 @default.
• W4319787054 hasConceptScore W4319787054C86339819 @default.
• W4319787054 hasConceptScore W4319787054C86803240 @default.
• W4319787054 hasConceptScore W4319787054C89423630 @default.
• W4319787054 hasConceptScore W4319787054C95282255 @default.
• W4319787054 hasIssue "3" @default.
• W4319787054 hasLocation W43197870541 @default.
• W4319787054 hasLocation W43197870542 @default.
• W4319787054 hasOpenAccess W4319787054 @default.
• W4319787054 hasPrimaryLocation W43197870541 @default.
• W4319787054 hasRelatedWork W1940806326 @default.
• W4319787054 hasRelatedWork W1991523530 @default.
• W4319787054 hasRelatedWork W2002128513 @default.
• W4319787054 hasRelatedWork W2022351915 @default.
• W4319787054 hasRelatedWork W2095569907 @default.
• W4319787054 hasRelatedWork W2138139293 @default.
• W4319787054 hasRelatedWork W2171277769 @default.
• W4319787054 hasRelatedWork W2171527366 @default.
• W4319787054 hasRelatedWork W4220995072 @default.
• W4319787054 hasRelatedWork W2092874662 @default.
• W4319787054 hasVolume "119" @default.
• W4319787054 isParatext "false" @default.
• W4319787054 isRetracted "false" @default.
• W4319787054 workType "article" @default.