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• W4319840245 abstract "Abstract L–DOPA decarboxylase (DDC) deficiency causes serious progressive neurodegenerative disorders. Developing a sensitive enzyme activity monitoring and inhibitors or activators screening approach is highly on demand for DDC deficiency diagnosis. Here, we report a simple and sensitive fluorescence supramolecular tandem assay based on reporter pair of cucurbit[7]uril and acridine orange for DDC activity monitoring continuously. Furthermore, this strategy demonstrates the potential of STA to screen inhibitors of DDC." @default.
• W4319840245 created "2023-02-11" @default.
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• W4319840245 date "2023-01-12" @default.
• W4319840245 modified "2023-10-12" @default.
• W4319840245 title "A Label‐Free and Continuous Fluorescence Detection for L–DOPA Decarboxylase Activity Based on Supramolecular Tandem Assay" @default.
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• W4319840245 doi "https://doi.org/10.1002/slct.202203646" @default.
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