Matches in SemOpenAlex for { <https://semopenalex.org/work/W4319943422> ?p ?o ?g. }
- W4319943422 endingPage "130324" @default.
- W4319943422 startingPage "130324" @default.
- W4319943422 abstract "Reactive oxygen species play a key role in cellular homeostasis and redox signaling at physiological levels, where excessive production affects the function and integrity of macromolecules, specifically proteins. Therefore, it is important to define radical-mediated proteotoxic stress in macrophages and identify target protein to prevent tissue dysfunction. A well employed, THP-1 cell line was utilized as in vitro model to study immune response and herein we employ immuno-spin trapping technique to investigate radical-mediated protein oxidation in macrophages. Hydroxyl radical formation along macrophage differentiation was confirmed by electron paramagnetic resonance along with confocal laser scanning microscopy using hydroxyphenyl fluorescein. Lipid peroxidation product, malondialdehyde, generated under experimental conditions as detected using swallow-tailed perylene derivative fluorescence observed by confocal laser scanning microscopy and high-performance liquid chromatography, respectively. The results obtained from this study warrant further corroboration and study of specific proteins involved in the macrophage activation and their role in inflammations." @default.
- W4319943422 created "2023-02-11" @default.
- W4319943422 creator A5008770577 @default.
- W4319943422 creator A5011302536 @default.
- W4319943422 creator A5030759077 @default.
- W4319943422 creator A5058420384 @default.
- W4319943422 date "2023-05-01" @default.
- W4319943422 modified "2023-10-16" @default.
- W4319943422 title "Detection and characterization of free oxygen radicals induced protein adduct formation in differentiating macrophages" @default.
- W4319943422 cites W145720774 @default.
- W4319943422 cites W1966393840 @default.
- W4319943422 cites W1971271779 @default.
- W4319943422 cites W1979416132 @default.
- W4319943422 cites W1986219645 @default.
- W4319943422 cites W1986940060 @default.
- W4319943422 cites W1991952977 @default.
- W4319943422 cites W1994871609 @default.
- W4319943422 cites W1998691842 @default.
- W4319943422 cites W2009855811 @default.
- W4319943422 cites W2016098182 @default.
- W4319943422 cites W2025639892 @default.
- W4319943422 cites W2068788903 @default.
- W4319943422 cites W2089088411 @default.
- W4319943422 cites W2093061584 @default.
- W4319943422 cites W2144596408 @default.
- W4319943422 cites W2147425799 @default.
- W4319943422 cites W2150029444 @default.
- W4319943422 cites W2158435581 @default.
- W4319943422 cites W2162166699 @default.
- W4319943422 cites W2162332607 @default.
- W4319943422 cites W2271695415 @default.
- W4319943422 cites W2282741333 @default.
- W4319943422 cites W2339267206 @default.
- W4319943422 cites W2560494879 @default.
- W4319943422 cites W2594039057 @default.
- W4319943422 cites W2622269865 @default.
- W4319943422 cites W2807906301 @default.
- W4319943422 cites W2884163420 @default.
- W4319943422 cites W2893278511 @default.
- W4319943422 cites W2914783314 @default.
- W4319943422 cites W2950384292 @default.
- W4319943422 cites W2954526477 @default.
- W4319943422 cites W2962070988 @default.
- W4319943422 cites W2991640993 @default.
- W4319943422 cites W2996927716 @default.
- W4319943422 cites W2999832851 @default.
- W4319943422 cites W3085512484 @default.
- W4319943422 cites W3102092593 @default.
- W4319943422 cites W3122227687 @default.
- W4319943422 cites W3133435951 @default.
- W4319943422 cites W3175390368 @default.
- W4319943422 cites W3200352397 @default.
- W4319943422 doi "https://doi.org/10.1016/j.bbagen.2023.130324" @default.
- W4319943422 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36775000" @default.
- W4319943422 hasPublicationYear "2023" @default.
- W4319943422 type Work @default.
- W4319943422 citedByCount "0" @default.
- W4319943422 crossrefType "journal-article" @default.
- W4319943422 hasAuthorship W4319943422A5008770577 @default.
- W4319943422 hasAuthorship W4319943422A5011302536 @default.
- W4319943422 hasAuthorship W4319943422A5030759077 @default.
- W4319943422 hasAuthorship W4319943422A5058420384 @default.
- W4319943422 hasConcept C12554922 @default.
- W4319943422 hasConcept C139066938 @default.
- W4319943422 hasConcept C178790620 @default.
- W4319943422 hasConcept C185592680 @default.
- W4319943422 hasConcept C202751555 @default.
- W4319943422 hasConcept C204389451 @default.
- W4319943422 hasConcept C2776151105 @default.
- W4319943422 hasConcept C2779178360 @default.
- W4319943422 hasConcept C2779189646 @default.
- W4319943422 hasConcept C2779244956 @default.
- W4319943422 hasConcept C2780829032 @default.
- W4319943422 hasConcept C32909587 @default.
- W4319943422 hasConcept C48349386 @default.
- W4319943422 hasConcept C55493867 @default.
- W4319943422 hasConcept C86803240 @default.
- W4319943422 hasConcept C95444343 @default.
- W4319943422 hasConceptScore W4319943422C12554922 @default.
- W4319943422 hasConceptScore W4319943422C139066938 @default.
- W4319943422 hasConceptScore W4319943422C178790620 @default.
- W4319943422 hasConceptScore W4319943422C185592680 @default.
- W4319943422 hasConceptScore W4319943422C202751555 @default.
- W4319943422 hasConceptScore W4319943422C204389451 @default.
- W4319943422 hasConceptScore W4319943422C2776151105 @default.
- W4319943422 hasConceptScore W4319943422C2779178360 @default.
- W4319943422 hasConceptScore W4319943422C2779189646 @default.
- W4319943422 hasConceptScore W4319943422C2779244956 @default.
- W4319943422 hasConceptScore W4319943422C2780829032 @default.
- W4319943422 hasConceptScore W4319943422C32909587 @default.
- W4319943422 hasConceptScore W4319943422C48349386 @default.
- W4319943422 hasConceptScore W4319943422C55493867 @default.
- W4319943422 hasConceptScore W4319943422C86803240 @default.
- W4319943422 hasConceptScore W4319943422C95444343 @default.
- W4319943422 hasIssue "5" @default.
- W4319943422 hasLocation W43199434221 @default.
- W4319943422 hasLocation W43199434222 @default.
- W4319943422 hasOpenAccess W4319943422 @default.