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• W4320014722 abstract "The liver is unusually susceptible to toxicant-induced injury due to its unique physiology and biochemistry, but current liver injury biomarkers have limited value beyond detection of the injury and the resulting impact on liver function. Better biomarkers are needed for (1) diagnosis and determination of etiology, (2) prognosis, and (3) preclinical assessment of the hepatotoxic liability of new drugs and xenobiotics. A number of biomarker candidates that may meet these needs have been identified over the last 10 years. In addition, several biomarkers with mechanistic importance have been proposed. In this chapter, we will briefly review current liver biomarkers and discuss the most popular emerging biomarker candidates. We will also discuss strengths and weaknesses of each and what work remains to be done to move the field forward." @default.
• W4320014722 created "2023-02-11" @default.
• W4320014722 creator A5031360889 @default.
• W4320014722 date "2023-01-01" @default.
• W4320014722 modified "2023-09-26" @default.
• W4320014722 title "Biomarkers of Liver Injury due to Toxic Agents: Progress, Current Applications, and Emerging Directions" @default.
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• W4320014722 doi "https://doi.org/10.1007/978-3-031-07392-2_14" @default.
• W4320014722 hasPublicationYear "2023" @default.
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