FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4320041310> ?p ?o ?g. }

• W4320041310 endingPage "2115" @default.
• W4320041310 startingPage "2106" @default.
• W4320041310 abstract "Abstract Background There are limited US data assessing adherence to surgical antimicrobial prophylaxis guidelines, particularly across a large, nationwide sample. Moreover, commonly prescribed inappropriate antimicrobial prophylaxis regimens remain unknown, hindering improvement initiatives. Methods We conducted a retrospective cohort study of adults who underwent elective craniotomy, hip replacement, knee replacement, spinal procedure, or hernia repair in 2019–2020 at hospitals in the PINC AI (Premier) Healthcare Database. We evaluated adherence of prophylaxis regimens, with respect to antimicrobial agents endorsed in the American Society of Health-System Pharmacist guidelines, accounting for patient antibiotic allergy and methicillin-resistant Staphylococcus aureus colonization status. We used multivariable logistic regression with random effects by hospital to evaluate associations between patient, procedural, and hospital characteristics and guideline adherence. Results Across 825 hospitals and 521 091 inpatient elective surgeries, 308 760 (59%) were adherent to prophylaxis guidelines. In adjusted analysis, adherence varied significantly by US Census division (adjusted OR [aOR] range: .61–1.61) and was significantly lower in 2020 compared with 2019 (aOR: .92; 95% CI: .91–.94; P &lt; .001). The most common reason for nonadherence was unnecessary vancomycin use. In a post hoc analysis, controlling for patient age, comorbidities, other nephrotoxic agent use, and patient and procedure characteristics, patients receiving cefazolin plus vancomycin had 19% higher odds of acute kidney injury (AKI) compared with patients receiving cefazolin alone (aOR: 1.19; 95% CI: 1.11–1.27; P &lt; .001). Conclusions Adherence to antimicrobial prophylaxis guidelines remains suboptimal, largely driven by unnecessary vancomycin use, which may increase the risk of AKI. Adherence decreased in the first year of the COVID-19 pandemic." @default.
• W4320041310 created "2023-02-12" @default.
• W4320041310 creator A5018437292 @default.
• W4320041310 creator A5030280540 @default.
• W4320041310 creator A5041551162 @default.
• W4320041310 creator A5068455454 @default.
• W4320041310 creator A5073854380 @default.
• W4320041310 creator A5079843231 @default.
• W4320041310 date "2023-02-12" @default.
• W4320041310 modified "2023-10-02" @default.
• W4320041310 title "Adherence to Antimicrobial Prophylaxis Guidelines for Elective Surgeries Across 825 US Hospitals, 2019–2020" @default.
• W4320041310 cites W1752621696 @default.
• W4320041310 cites W1868703151 @default.
• W4320041310 cites W1889227901 @default.
• W4320041310 cites W1981145318 @default.
• W4320041310 cites W2040608759 @default.
• W4320041310 cites W2048229979 @default.
• W4320041310 cites W2068584380 @default.
• W4320041310 cites W2092254521 @default.
• W4320041310 cites W2119561943 @default.
• W4320041310 cites W2132117678 @default.
• W4320041310 cites W2136058993 @default.
• W4320041310 cites W2142810382 @default.
• W4320041310 cites W2151584197 @default.
• W4320041310 cites W2160647339 @default.
• W4320041310 cites W2164412910 @default.
• W4320041310 cites W2181435932 @default.
• W4320041310 cites W2523533059 @default.
• W4320041310 cites W2610936380 @default.
• W4320041310 cites W2625336087 @default.
• W4320041310 cites W2725030136 @default.
• W4320041310 cites W2735690002 @default.
• W4320041310 cites W2887806376 @default.
• W4320041310 cites W2942184614 @default.
• W4320041310 cites W2984510662 @default.
• W4320041310 cites W3008514343 @default.
• W4320041310 cites W3011719258 @default.
• W4320041310 cites W3021928067 @default.
• W4320041310 cites W3024247247 @default.
• W4320041310 cites W3026423035 @default.
• W4320041310 cites W3081368778 @default.
• W4320041310 cites W3085540854 @default.
• W4320041310 cites W3110410930 @default.
• W4320041310 cites W3110839392 @default.
• W4320041310 cites W3124303668 @default.
• W4320041310 cites W3198525884 @default.
• W4320041310 cites W4200472715 @default.
• W4320041310 cites W4283376285 @default.
• W4320041310 doi "https://doi.org/10.1093/cid/ciad077" @default.
• W4320041310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36774539" @default.
• W4320041310 hasPublicationYear "2023" @default.
• W4320041310 type Work @default.
• W4320041310 citedByCount "6" @default.
• W4320041310 countsByYear W43200413102023 @default.
• W4320041310 crossrefType "journal-article" @default.
• W4320041310 hasAuthorship W4320041310A5018437292 @default.
• W4320041310 hasAuthorship W4320041310A5030280540 @default.
• W4320041310 hasAuthorship W4320041310A5041551162 @default.
• W4320041310 hasAuthorship W4320041310A5068455454 @default.
• W4320041310 hasAuthorship W4320041310A5073854380 @default.
• W4320041310 hasAuthorship W4320041310A5079843231 @default.
• W4320041310 hasBestOaLocation W43200413101 @default.
• W4320041310 hasConcept C126322002 @default.
• W4320041310 hasConcept C142724271 @default.
• W4320041310 hasConcept C156957248 @default.
• W4320041310 hasConcept C167135981 @default.
• W4320041310 hasConcept C177713679 @default.
• W4320041310 hasConcept C194828623 @default.
• W4320041310 hasConcept C2776040555 @default.
• W4320041310 hasConcept C2778353156 @default.
• W4320041310 hasConcept C2778602436 @default.
• W4320041310 hasConcept C2778980435 @default.
• W4320041310 hasConcept C2779489039 @default.
• W4320041310 hasConcept C2780182762 @default.
• W4320041310 hasConcept C501593827 @default.
• W4320041310 hasConcept C523546767 @default.
• W4320041310 hasConcept C54355233 @default.
• W4320041310 hasConcept C71924100 @default.
• W4320041310 hasConcept C86803240 @default.
• W4320041310 hasConcept C89423630 @default.
• W4320041310 hasConcept C94665300 @default.
• W4320041310 hasConceptScore W4320041310C126322002 @default.
• W4320041310 hasConceptScore W4320041310C142724271 @default.
• W4320041310 hasConceptScore W4320041310C156957248 @default.
• W4320041310 hasConceptScore W4320041310C167135981 @default.
• W4320041310 hasConceptScore W4320041310C177713679 @default.
• W4320041310 hasConceptScore W4320041310C194828623 @default.
• W4320041310 hasConceptScore W4320041310C2776040555 @default.
• W4320041310 hasConceptScore W4320041310C2778353156 @default.
• W4320041310 hasConceptScore W4320041310C2778602436 @default.
• W4320041310 hasConceptScore W4320041310C2778980435 @default.
• W4320041310 hasConceptScore W4320041310C2779489039 @default.
• W4320041310 hasConceptScore W4320041310C2780182762 @default.
• W4320041310 hasConceptScore W4320041310C501593827 @default.
• W4320041310 hasConceptScore W4320041310C523546767 @default.
• W4320041310 hasConceptScore W4320041310C54355233 @default.
• W4320041310 hasConceptScore W4320041310C71924100 @default.
• W4320041310 hasConceptScore W4320041310C86803240 @default.

• next