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- W4320076052 abstract "Introduction : The degree of differentiation of prostate cancer is evaluated by the Gleason score (GS). Patients who undergo radical prostatectomy (RP) have their GS determined twice—first, during the biopsy, and second, after the RP. The two GSs often differ. Aim: We have studied how the change of GS affects biochemical progression-free survival (BPFS) of the patients. Materials and Methods: The patients were divided into three groups. Group 1—GS of the biopsy was equal to those of the RP; Group 2—GS of the biopsy increased after the RP; Group 3—GS of the biopsy decreased after the RP. Pearson's chi square test, Mann-Whitney U test, and the Kaplan-Meier test were used to evaluate the difference in the BPFS in the three groups. Results: The patients available for analysis were 111—42 patients in Group 1, 40 patients in Group 2, and 29 patients in Group 3. A significantly better survival was proven for the patients in Group 1 compared with Groups 2 and 3. Discussion: Group 2 had the worst prognosis expected—here the GS increased. We proved that Group 3 also had bad prognosis although here the GS improved. Group 1 had the best prognosis. Conclusion: The likely explanation of these differences in BPFS is that the GS from the needle biopsy also has prognostic significance which is in accordance with the literature data analyzed in the text." @default.
- W4320076052 created "2023-02-12" @default.
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- W4320076052 date "2022-04-14" @default.
- W4320076052 modified "2023-09-30" @default.
- W4320076052 title "The effect of the Gleason score change on biochemical progression-free survival" @default.
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- W4320076052 doi "https://doi.org/10.14748/ssm.v54i2.8213" @default.
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