Matches in SemOpenAlex for { <https://semopenalex.org/work/W4320169880> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W4320169880 abstract "Noncompliance is a common intercurrent event in randomized clinical trials that raises important questions about analytical objectives and approaches. Motivated by the Multiple Risk Factor Intervention Trial (MRFIT), we consider how to estimate the average treatment effect (ATE) in randomized trials with all-or-none compliance. Confounding is a major challenge in estimating the ATE, and conventional methods for confounding adjustment typically require the assumption of no unmeasured confounders which may be difficult to justify. Using randomized treatment assignment as an instrumental variable, the ATE can be identified in the presence of unmeasured confounders under suitable assumptions, including an assumption that limits the effect-modifying activities of unmeasured confounders. We describe and compare several estimation methods based on different modeling assumptions. Some of these methods are able to incorporate information from auxiliary covariates for improved efficiency without introducing bias. The different methods are compared in a simulation study and applied to the MRFIT." @default.
- W4320169880 created "2023-02-13" @default.
- W4320169880 creator A5019005078 @default.
- W4320169880 creator A5021104158 @default.
- W4320169880 creator A5031896811 @default.
- W4320169880 creator A5056611428 @default.
- W4320169880 date "2023-03-01" @default.
- W4320169880 modified "2023-09-26" @default.
- W4320169880 title "Estimating the average treatment effect in randomized clinical trials with all-or-none compliance" @default.
- W4320169880 cites W1519840136 @default.
- W4320169880 cites W2009187570 @default.
- W4320169880 cites W2019685888 @default.
- W4320169880 cites W2026638921 @default.
- W4320169880 cites W2032324394 @default.
- W4320169880 cites W2082299845 @default.
- W4320169880 cites W2085227190 @default.
- W4320169880 cites W2121983778 @default.
- W4320169880 cites W2137370054 @default.
- W4320169880 cites W2144512268 @default.
- W4320169880 cites W2333325822 @default.
- W4320169880 cites W2409368529 @default.
- W4320169880 cites W2963867565 @default.
- W4320169880 cites W3124658416 @default.
- W4320169880 cites W3127376134 @default.
- W4320169880 cites W4234712938 @default.
- W4320169880 cites W4239621349 @default.
- W4320169880 cites W4239728164 @default.
- W4320169880 cites W4240519598 @default.
- W4320169880 cites W4241809229 @default.
- W4320169880 cites W4245148494 @default.
- W4320169880 doi "https://doi.org/10.1214/22-aoas1627" @default.
- W4320169880 hasPublicationYear "2023" @default.
- W4320169880 type Work @default.
- W4320169880 citedByCount "0" @default.
- W4320169880 crossrefType "journal-article" @default.
- W4320169880 hasAuthorship W4320169880A5019005078 @default.
- W4320169880 hasAuthorship W4320169880A5021104158 @default.
- W4320169880 hasAuthorship W4320169880A5031896811 @default.
- W4320169880 hasAuthorship W4320169880A5056611428 @default.
- W4320169880 hasConcept C105795698 @default.
- W4320169880 hasConcept C119043178 @default.
- W4320169880 hasConcept C141071460 @default.
- W4320169880 hasConcept C149782125 @default.
- W4320169880 hasConcept C162144332 @default.
- W4320169880 hasConcept C168563851 @default.
- W4320169880 hasConcept C33923547 @default.
- W4320169880 hasConcept C71924100 @default.
- W4320169880 hasConcept C77350462 @default.
- W4320169880 hasConceptScore W4320169880C105795698 @default.
- W4320169880 hasConceptScore W4320169880C119043178 @default.
- W4320169880 hasConceptScore W4320169880C141071460 @default.
- W4320169880 hasConceptScore W4320169880C149782125 @default.
- W4320169880 hasConceptScore W4320169880C162144332 @default.
- W4320169880 hasConceptScore W4320169880C168563851 @default.
- W4320169880 hasConceptScore W4320169880C33923547 @default.
- W4320169880 hasConceptScore W4320169880C71924100 @default.
- W4320169880 hasConceptScore W4320169880C77350462 @default.
- W4320169880 hasIssue "1" @default.
- W4320169880 hasLocation W43201698801 @default.
- W4320169880 hasOpenAccess W4320169880 @default.
- W4320169880 hasPrimaryLocation W43201698801 @default.
- W4320169880 hasRelatedWork W194268815 @default.
- W4320169880 hasRelatedWork W1975567997 @default.
- W4320169880 hasRelatedWork W1975652640 @default.
- W4320169880 hasRelatedWork W1998482801 @default.
- W4320169880 hasRelatedWork W2049720791 @default.
- W4320169880 hasRelatedWork W2147646215 @default.
- W4320169880 hasRelatedWork W2159767831 @default.
- W4320169880 hasRelatedWork W2167796745 @default.
- W4320169880 hasRelatedWork W2790436231 @default.
- W4320169880 hasRelatedWork W3005275560 @default.
- W4320169880 hasVolume "17" @default.
- W4320169880 isParatext "false" @default.
- W4320169880 isRetracted "false" @default.
- W4320169880 workType "article" @default.