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• W4320495671 abstract "Nasal deformities due to various causes affect the aesthetics and use of the nose, in which case rhinoplasty is necessary. However, the lack of cartilage for grafting has been a major problem and tissue engineering seems to be a promising solution. 3D bioprinting has become one of the most advanced tissue engineering methods. To construct ideal cartilage, bio-ink, seed cells, growth factors and other methods to promote chondrogenesis should be considered and weighed carefully. With continuous progress in the field, bio-ink choices are becoming increasingly abundant, from a single hydrogel to a combination of hydrogels with various characteristics, and more 3D bioprinting methods are also emerging. Adipose-derived stem cells (ADSCs) have become one of the most popular seed cells in cartilage 3D bioprinting, owing to their abundance, excellent proliferative potential, minimal morbidity during harvest and lack of ethical considerations limitations. In addition, the co-culture of ADSCs and chondrocytes is commonly used to achieve better chondrogenesis. To promote chondrogenic differentiation of ADSCs and construct ideal highly bionic tissue-engineered cartilage, researchers have used a variety of methods, including adding appropriate growth factors, applying biomechanical stimuli and reducing oxygen tension. According to the process and sequence of cartilage 3D bioprinting, this review summarizes and discusses the selection of hydrogel and seed cells (centered on ADSCs), the design of printing, and methods for inducing the chondrogenesis of ADSCs." @default.
• W4320495671 created "2023-02-14" @default.
• W4320495671 creator A5013121280 @default.
• W4320495671 creator A5020085668 @default.
• W4320495671 creator A5042745108 @default.
• W4320495671 creator A5045397634 @default.
• W4320495671 creator A5045545412 @default.
• W4320495671 creator A5047229415 @default.
• W4320495671 creator A5047835985 @default.
• W4320495671 date "2023-02-12" @default.
• W4320495671 modified "2023-10-10" @default.
• W4320495671 title "Cartilage <scp>3D</scp> bioprinting for rhinoplasty using adipose‐derived stem cells as seed cells: Review and recent advances" @default.
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