FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4320723786> ?p ?o ?g. }

• W4320723786 abstract "Neutralizing antibody (NtAb) levels are key indicators in the development and evaluation of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccines. Establishing a unified and reliable WHO International Standard (IS) for NtAb is crucial for the calibration and harmonization of NtAb detection assays. National and other WHO secondary standards are key links in the transfer of IS to working standards but are often overlooked. The Chinese National Standard (NS) and WHO IS were developed by China and WHO in September and December 2020, respectively, the application of which prompted and coordinated sero-detection of vaccine and therapy globally. Currently, a second-generation Chinese NS is urgently required owing to the depletion of stocks and need for calibration to the WHO IS. The Chinese National Institutes for Food and Drug Control (NIFDC) developed two candidate NSs (samples 33 and 66–99) traced to the IS according to the WHO manual for the establishment of national secondary standards through a collaborative study of nine experienced labs. Either NS candidate can reduce the systematic error among different laboratories and the difference between the live virus neutralization (Neut) and pseudovirus neutralization (PsN) methods, ensuring the accuracy and comparability of NtAb test results among multiple labs and methods, especially for samples 66–99. At present, samples 66–99 have been approved as the second-generation NS, which is the first NS calibrated tracing to the IS with 580 (460–740) International Units (IU)/mL and 580 (520–640) IU/mL by Neut and PsN, respectively. The use of standards improves the reliability and comparability of NtAb detection, ensuring the continuity of the use of the IS unitage, which effectively promotes the development and application of SARS-CoV-2 vaccines in China." @default.
• W4320723786 created "2023-02-15" @default.
• W4320723786 creator A5000245536 @default.
• W4320723786 creator A5002696746 @default.
• W4320723786 creator A5009709781 @default.
• W4320723786 creator A5013958114 @default.
• W4320723786 creator A5014756786 @default.
• W4320723786 creator A5022321727 @default.
• W4320723786 creator A5035576538 @default.
• W4320723786 creator A5037902083 @default.
• W4320723786 creator A5046126762 @default.
• W4320723786 creator A5047079042 @default.
• W4320723786 creator A5054871862 @default.
• W4320723786 creator A5055252785 @default.
• W4320723786 creator A5056753391 @default.
• W4320723786 creator A5059293587 @default.
• W4320723786 creator A5070730907 @default.
• W4320723786 creator A5071391600 @default.
• W4320723786 creator A5072199810 @default.
• W4320723786 creator A5077449848 @default.
• W4320723786 creator A5081751322 @default.
• W4320723786 date "2023-02-14" @default.
• W4320723786 modified "2023-09-25" @default.
• W4320723786 title "Establishment of national standard for anti-SARS-Cov-2 neutralizing antibody in China: The first National Standard calibration traceability to the WHO International Standard" @default.
• W4320723786 cites W1989895753 @default.
• W4320723786 cites W3012650581 @default.
• W4320723786 cites W3013660050 @default.
• W4320723786 cites W3114250596 @default.
• W4320723786 cites W3120149972 @default.
• W4320723786 cites W3134208712 @default.
• W4320723786 cites W3155000349 @default.
• W4320723786 cites W3162599850 @default.
• W4320723786 cites W3163785571 @default.
• W4320723786 cites W3169503674 @default.
• W4320723786 cites W3174017401 @default.
• W4320723786 cites W3210891969 @default.
• W4320723786 cites W4200278787 @default.
• W4320723786 cites W4220807057 @default.
• W4320723786 cites W4224274105 @default.
• W4320723786 cites W4224930389 @default.
• W4320723786 cites W4224950176 @default.
• W4320723786 doi "https://doi.org/10.3389/fimmu.2023.1107639" @default.
• W4320723786 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36865542" @default.
• W4320723786 hasPublicationYear "2023" @default.
• W4320723786 type Work @default.
• W4320723786 citedByCount "0" @default.
• W4320723786 crossrefType "journal-article" @default.
• W4320723786 hasAuthorship W4320723786A5000245536 @default.
• W4320723786 hasAuthorship W4320723786A5002696746 @default.
• W4320723786 hasAuthorship W4320723786A5009709781 @default.
• W4320723786 hasAuthorship W4320723786A5013958114 @default.
• W4320723786 hasAuthorship W4320723786A5014756786 @default.
• W4320723786 hasAuthorship W4320723786A5022321727 @default.
• W4320723786 hasAuthorship W4320723786A5035576538 @default.
• W4320723786 hasAuthorship W4320723786A5037902083 @default.
• W4320723786 hasAuthorship W4320723786A5046126762 @default.
• W4320723786 hasAuthorship W4320723786A5047079042 @default.
• W4320723786 hasAuthorship W4320723786A5054871862 @default.
• W4320723786 hasAuthorship W4320723786A5055252785 @default.
• W4320723786 hasAuthorship W4320723786A5056753391 @default.
• W4320723786 hasAuthorship W4320723786A5059293587 @default.
• W4320723786 hasAuthorship W4320723786A5070730907 @default.
• W4320723786 hasAuthorship W4320723786A5071391600 @default.
• W4320723786 hasAuthorship W4320723786A5072199810 @default.
• W4320723786 hasAuthorship W4320723786A5077449848 @default.
• W4320723786 hasAuthorship W4320723786A5081751322 @default.
• W4320723786 hasBestOaLocation W43207237861 @default.
• W4320723786 hasConcept C105795698 @default.
• W4320723786 hasConcept C114614502 @default.
• W4320723786 hasConcept C121332964 @default.
• W4320723786 hasConcept C126322002 @default.
• W4320723786 hasConcept C153876917 @default.
• W4320723786 hasConcept C159047783 @default.
• W4320723786 hasConcept C165838908 @default.
• W4320723786 hasConcept C17744445 @default.
• W4320723786 hasConcept C191935318 @default.
• W4320723786 hasConcept C197947376 @default.
• W4320723786 hasConcept C199539241 @default.
• W4320723786 hasConcept C24890656 @default.
• W4320723786 hasConcept C2776588390 @default.
• W4320723786 hasConcept C2779134260 @default.
• W4320723786 hasConcept C2779962950 @default.
• W4320723786 hasConcept C2992690752 @default.
• W4320723786 hasConcept C3007834351 @default.
• W4320723786 hasConcept C3008058167 @default.
• W4320723786 hasConcept C31903555 @default.
• W4320723786 hasConcept C33923547 @default.
• W4320723786 hasConcept C40993552 @default.
• W4320723786 hasConcept C41008148 @default.
• W4320723786 hasConcept C524204448 @default.
• W4320723786 hasConcept C71924100 @default.
• W4320723786 hasConcept C76155785 @default.
• W4320723786 hasConcept C86803240 @default.
• W4320723786 hasConceptScore W4320723786C105795698 @default.
• W4320723786 hasConceptScore W4320723786C114614502 @default.
• W4320723786 hasConceptScore W4320723786C121332964 @default.
• W4320723786 hasConceptScore W4320723786C126322002 @default.
• W4320723786 hasConceptScore W4320723786C153876917 @default.
• W4320723786 hasConceptScore W4320723786C159047783 @default.
• W4320723786 hasConceptScore W4320723786C165838908 @default.

• next