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- W4320728497 endingPage "480" @default.
- W4320728497 startingPage "480" @default.
- W4320728497 abstract "The mitochondrion is also a major site for maintaining redox homeostasis between reactive oxygen species (ROS) generation and scavenging. The quantity, quality, and functional integrity of mitochondria are crucial for regulating intracellular homeostasis and maintaining the normal physiological function of cells. The role of oxidative stress in human disease is well established, particularly in inflammatory bowel disease and gastrointestinal mucosal diseases. Oxidative stress could result from an imbalance between ROS and the antioxidative system. Mitochondria are both the main sites of production and the main target of ROS. It is a vicious cycle in which initial ROS-induced mitochondrial damage enhanced ROS production that, in turn, leads to further mitochondrial damage and eventually massive intestinal cell death. Oxidative damage can be significantly mitigated by mitophagy, which clears damaged mitochondria. In this review, we aimed to review the molecular mechanisms involved in the regulation of mitophagy and oxidative stress and their relationship in some intestinal diseases. We believe the reviews can provide new ideas and a scientific basis for researching antioxidants and preventing diseases related to oxidative damage." @default.
- W4320728497 created "2023-02-15" @default.
- W4320728497 creator A5011487190 @default.
- W4320728497 creator A5020147975 @default.
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- W4320728497 creator A5034332113 @default.
- W4320728497 creator A5058788330 @default.
- W4320728497 creator A5079795759 @default.
- W4320728497 date "2023-02-14" @default.
- W4320728497 modified "2023-10-17" @default.
- W4320728497 title "Role of Mitophagy in Regulating Intestinal Oxidative Damage" @default.
- W4320728497 cites W1787754175 @default.
- W4320728497 cites W1966995952 @default.
- W4320728497 cites W1968284620 @default.
- W4320728497 cites W1977842144 @default.
- W4320728497 cites W1980949357 @default.
- W4320728497 cites W1992947862 @default.
- W4320728497 cites W1994442675 @default.
- W4320728497 cites W1995305184 @default.
- W4320728497 cites W1996625702 @default.
- W4320728497 cites W1998084948 @default.
- W4320728497 cites W2004723568 @default.
- W4320728497 cites W2007958856 @default.
- W4320728497 cites W2008443866 @default.
- W4320728497 cites W2009734791 @default.
- W4320728497 cites W2013642338 @default.
- W4320728497 cites W2022632625 @default.
- W4320728497 cites W2023448800 @default.
- W4320728497 cites W2033448006 @default.
- W4320728497 cites W2033885016 @default.
- W4320728497 cites W2041255615 @default.
- W4320728497 cites W2042455211 @default.
- W4320728497 cites W2045611938 @default.
- W4320728497 cites W2049016912 @default.
- W4320728497 cites W2053894876 @default.
- W4320728497 cites W2054085389 @default.
- W4320728497 cites W2057057259 @default.
- W4320728497 cites W2062671133 @default.
- W4320728497 cites W2068982039 @default.
- W4320728497 cites W2083101794 @default.
- W4320728497 cites W2089371584 @default.
- W4320728497 cites W2103230459 @default.
- W4320728497 cites W2104412320 @default.
- W4320728497 cites W2104551034 @default.
- W4320728497 cites W2114806766 @default.
- W4320728497 cites W2117224297 @default.
- W4320728497 cites W2119626361 @default.
- W4320728497 cites W2121966499 @default.
- W4320728497 cites W2127157806 @default.
- W4320728497 cites W2129181731 @default.
- W4320728497 cites W2132497116 @default.
- W4320728497 cites W2147929482 @default.
- W4320728497 cites W2148080180 @default.
- W4320728497 cites W2154020258 @default.
- W4320728497 cites W2155017178 @default.
- W4320728497 cites W2156356581 @default.
- W4320728497 cites W2164175488 @default.
- W4320728497 cites W2172786635 @default.
- W4320728497 cites W2229506676 @default.
- W4320728497 cites W2232974198 @default.
- W4320728497 cites W2240173075 @default.
- W4320728497 cites W2256422231 @default.
- W4320728497 cites W2312386152 @default.
- W4320728497 cites W2337123977 @default.
- W4320728497 cites W2557913761 @default.
- W4320728497 cites W2560103221 @default.
- W4320728497 cites W2560539696 @default.
- W4320728497 cites W2562998505 @default.
- W4320728497 cites W2566705091 @default.
- W4320728497 cites W2567467113 @default.
- W4320728497 cites W2593695507 @default.
- W4320728497 cites W2601831406 @default.
- W4320728497 cites W2616526198 @default.
- W4320728497 cites W2730120915 @default.
- W4320728497 cites W2744583165 @default.
- W4320728497 cites W2745198396 @default.
- W4320728497 cites W2762129136 @default.
- W4320728497 cites W2785105763 @default.
- W4320728497 cites W2789860518 @default.
- W4320728497 cites W2790628760 @default.
- W4320728497 cites W2792651356 @default.
- W4320728497 cites W2803714880 @default.
- W4320728497 cites W2808721432 @default.
- W4320728497 cites W2809022720 @default.
- W4320728497 cites W2810118634 @default.
- W4320728497 cites W2887998229 @default.
- W4320728497 cites W2889913345 @default.
- W4320728497 cites W2895588157 @default.
- W4320728497 cites W2897580028 @default.
- W4320728497 cites W2903402969 @default.
- W4320728497 cites W2904202908 @default.
- W4320728497 cites W2905138175 @default.
- W4320728497 cites W2905213246 @default.
- W4320728497 cites W2907107307 @default.
- W4320728497 cites W2907190516 @default.
- W4320728497 cites W2911248861 @default.
- W4320728497 cites W2912937500 @default.
- W4320728497 cites W2937748466 @default.