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- W4320857052 abstract "Following significant advancements in cancer therapeutics and survival, the risk of cancer therapy-related cardiotoxicity (CTRC) is increasingly recognized. With ongoing efforts to reduce cardiovascular morbidity and mortality in cancer patients and survivors, cardiac biomarkers have been studied for both risk stratification and monitoring during and after therapy to detect subclinical disease. This article will review the utility for biomarker use throughout the cancer care continuum.A recent meta-analysis shows utility for troponin in monitoring patients at risk for CTRC during cancer therapy. The role for natriuretic peptides is less clear but may be useful in patients receiving proteasome inhibitors. Early studies explore use of myeloperoxidase, growth differentiation factor 15, galectin 3, micro-RNA, and others as novel biomarkers in CTRC. Biomarkers have potential to identify subclinical CTRC and may reveal opportunities for early intervention. Further research is needed to elucidate optimal biomarkers and surveillance strategies." @default.
- W4320857052 created "2023-02-16" @default.
- W4320857052 creator A5003681797 @default.
- W4320857052 creator A5013641173 @default.
- W4320857052 creator A5013864544 @default.
- W4320857052 creator A5014249119 @default.
- W4320857052 creator A5020694375 @default.
- W4320857052 creator A5042135626 @default.
- W4320857052 creator A5076681797 @default.
- W4320857052 date "2023-02-15" @default.
- W4320857052 modified "2023-10-17" @default.
- W4320857052 title "Recent Advances in Serum Biomarkers for Risk Stratification and Patient Management in Cardio-Oncology" @default.
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