FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4320901975> ?p ?o ?g. }

• W4320901975 endingPage "23" @default.
• W4320901975 startingPage "13" @default.
• W4320901975 abstract "Gastric cancer is a common malignant tumor with a relatively poor prognosis after surgery. Non-coding RNA may serve as biomarkers for the progression and prognosis of various cancers. The clinical significance and biological function of lncRNA TRHDE-AS1 and miR-1275 in gastric cancer were assessed in this study. 119 paired tissues were selected with adequate clinical information. Quantitative real-time polymerase chain reaction (qRT-PCR) was used to determine the expression level of lncRNA TRHDE-AS1 and miR-1275 in gastric cancer tissues and cells. The association between lncRNA TRHDE-AS1 or miR-1275 expression and the clinicopathological features of patients was analyzed by the Pearson Chi-square test. Kaplan-Meier analysis and Multi-variate Cox proportional regression analysis were utilized to evaluate the prognostic value of lncRNA TRHDE-AS1 and miR-1275. Finally, the effect of TRHDE-AS1 binding to miR-1275 on the gastric cancer cellular process was investigated by CCK-8 and Transwell assay. LncRNA TRHDE-AS1 was found to be downregulated in gastric cancer tissues and cells, but miR-1275 upregulated, which both showed significant associations with clinical pathology of gastric cancer patients (including TNM stage and lymph node metastasis) and a poor prognosis. LncRNA TRHDE-AS1 and miR-1275 can be considered two independent prognostic factors for gastric cancer. Furthermore, the upregulation of lncRNA TRHDE-AS1 inhibited cell proliferation, migration, and invasion of gastric cancer partly by miR-1275. LncRNA TRHDE-AS1/miR-1275 axis may be involved in the progression of gastric cancer and can be promising prognostic factors, which may provide new insights into the treatment of gastric cancer." @default.
• W4320901975 created "2023-02-16" @default.
• W4320901975 creator A5018950191 @default.
• W4320901975 creator A5032237120 @default.
• W4320901975 creator A5054368220 @default.
• W4320901975 date "2023-01-01" @default.
• W4320901975 modified "2023-09-30" @default.
• W4320901975 title "LncRNA TRHDE-AS1 and MiR-1275 as Promising Prognostic Biomarkers and Effects on Tumor Cell Progression in Gastric Cancer" @default.
• W4320901975 cites W1936029254 @default.
• W4320901975 cites W2017138250 @default.
• W4320901975 cites W2048724765 @default.
• W4320901975 cites W2116168949 @default.
• W4320901975 cites W2136222002 @default.
• W4320901975 cites W2162547088 @default.
• W4320901975 cites W2172967221 @default.
• W4320901975 cites W2179886188 @default.
• W4320901975 cites W2221837786 @default.
• W4320901975 cites W2293880235 @default.
• W4320901975 cites W2415650516 @default.
• W4320901975 cites W2431102825 @default.
• W4320901975 cites W2514258009 @default.
• W4320901975 cites W2530597079 @default.
• W4320901975 cites W2561353898 @default.
• W4320901975 cites W2735126203 @default.
• W4320901975 cites W2810324767 @default.
• W4320901975 cites W2861975976 @default.
• W4320901975 cites W2895926103 @default.
• W4320901975 cites W2901259002 @default.
• W4320901975 cites W2904326242 @default.
• W4320901975 cites W2935936692 @default.
• W4320901975 cites W2946567447 @default.
• W4320901975 cites W2966150929 @default.
• W4320901975 cites W2997680837 @default.
• W4320901975 cites W3012615718 @default.
• W4320901975 cites W3033366394 @default.
• W4320901975 cites W3111568800 @default.
• W4320901975 cites W3126297673 @default.
• W4320901975 cites W3129181290 @default.
• W4320901975 cites W3135894931 @default.
• W4320901975 cites W4210990885 @default.
• W4320901975 doi "https://doi.org/10.1620/tjem.2023.j009" @default.
• W4320901975 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36792178" @default.
• W4320901975 hasPublicationYear "2023" @default.
• W4320901975 type Work @default.
• W4320901975 citedByCount "0" @default.
• W4320901975 crossrefType "journal-article" @default.
• W4320901975 hasAuthorship W4320901975A5018950191 @default.
• W4320901975 hasAuthorship W4320901975A5032237120 @default.
• W4320901975 hasAuthorship W4320901975A5054368220 @default.
• W4320901975 hasBestOaLocation W43209019751 @default.
• W4320901975 hasConcept C104317684 @default.
• W4320901975 hasConcept C121608353 @default.
• W4320901975 hasConcept C126322002 @default.
• W4320901975 hasConcept C127561419 @default.
• W4320901975 hasConcept C143998085 @default.
• W4320901975 hasConcept C146357865 @default.
• W4320901975 hasConcept C151730666 @default.
• W4320901975 hasConcept C2779013556 @default.
• W4320901975 hasConcept C2779256057 @default.
• W4320901975 hasConcept C2781018059 @default.
• W4320901975 hasConcept C29537977 @default.
• W4320901975 hasConcept C502942594 @default.
• W4320901975 hasConcept C50382708 @default.
• W4320901975 hasConcept C55493867 @default.
• W4320901975 hasConcept C62203573 @default.
• W4320901975 hasConcept C71924100 @default.
• W4320901975 hasConcept C86803240 @default.
• W4320901975 hasConceptScore W4320901975C104317684 @default.
• W4320901975 hasConceptScore W4320901975C121608353 @default.
• W4320901975 hasConceptScore W4320901975C126322002 @default.
• W4320901975 hasConceptScore W4320901975C127561419 @default.
• W4320901975 hasConceptScore W4320901975C143998085 @default.
• W4320901975 hasConceptScore W4320901975C146357865 @default.
• W4320901975 hasConceptScore W4320901975C151730666 @default.
• W4320901975 hasConceptScore W4320901975C2779013556 @default.
• W4320901975 hasConceptScore W4320901975C2779256057 @default.
• W4320901975 hasConceptScore W4320901975C2781018059 @default.
• W4320901975 hasConceptScore W4320901975C29537977 @default.
• W4320901975 hasConceptScore W4320901975C502942594 @default.
• W4320901975 hasConceptScore W4320901975C50382708 @default.
• W4320901975 hasConceptScore W4320901975C55493867 @default.
• W4320901975 hasConceptScore W4320901975C62203573 @default.
• W4320901975 hasConceptScore W4320901975C71924100 @default.
• W4320901975 hasConceptScore W4320901975C86803240 @default.
• W4320901975 hasIssue "1" @default.
• W4320901975 hasLocation W43209019751 @default.
• W4320901975 hasLocation W43209019752 @default.
• W4320901975 hasOpenAccess W4320901975 @default.
• W4320901975 hasPrimaryLocation W43209019751 @default.
• W4320901975 hasRelatedWork W1976172407 @default.
• W4320901975 hasRelatedWork W2086968193 @default.
• W4320901975 hasRelatedWork W2580637054 @default.
• W4320901975 hasRelatedWork W2772993264 @default.
• W4320901975 hasRelatedWork W2806814376 @default.
• W4320901975 hasRelatedWork W2971664433 @default.
• W4320901975 hasRelatedWork W2985559814 @default.
• W4320901975 hasRelatedWork W3003836586 @default.
• W4320901975 hasRelatedWork W3172687238 @default.

• next