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- W4320921337 abstract "Oligochitosan (OC) from shrimp shells derived chitosan was prepared using subcritical water hydrolysis (SWH) and their physicochemical and bio-functional properties were observed in this study. Reaction time of SWH was varied from 15 min to 60 min and the temperature from 140 °C to 170 °C. Gel permeation chromatography (GPC) confirmed that the molecular weight of the chitosan hydrolysate (CH) at 170 °C/15 min was obtained at 3.06 kDa. Fourier transform infrared and X-ray diffraction spectroscopy confirmed the conversion of OC from CH. Bio-functionality of CH was tested on the basis of antioxidant, antimicrobial, and anticancer activities. The ability of OC to act against the pancreatic cancer cell line Panc 1 was analyzed by MTT assay and Syto 9/PI fluorescent techniques. The MTT assay indicated that the maximum cytotoxicity was revealed by OC (170 °C/15 min) at 500 µg/mL. This research revealed that SWH can be an efficient method for the production of OC." @default.
- W4320921337 created "2023-02-16" @default.
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- W4320921337 date "2023-05-01" @default.
- W4320921337 modified "2023-09-29" @default.
- W4320921337 title "Oligochitosan recovered from shrimp shells through subcritical water hydrolysis: Molecular size reduction and biological activities" @default.
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- W4320921337 doi "https://doi.org/10.1016/j.supflu.2023.105868" @default.
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