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• W4321000864 abstract "From 1978 to 1988, 697 patients with a mean age of 48 ± 11 years (range 5 to 75 years) received a Sorin tilting-disc prosthesis; 358 had had aortic valve replacement, 247 mitral valve replacement, and 92 mitral and aortic valve replacement. Operative mortality rates were 7.8%, 11.3%, and 10.8%, respectively, in the three groups. Cumulative duration of follow-up is 1650 patient-years for aortic valve replacement (maximum follow-up 11.4 years), 963 patient-years for mitral valve replacement (maximum follow-up 9.9 years) and 328 patient-years for mitral and aortic valve replacement (maximum follow-up 9.4 years). Actuarial survival at 9 years is 72% ±4% after mitral valve replacement, 70% ±3% after aortic valve replacement, and 50% ± 12% after mitral and aortic valve replacement, and actuarial freedom from valve-related deaths is 97% ±2% after mitral valve replacement, 92% ±2% after aortic valve replacement, and 62% ± 15% after mitral and aortic valve replacement. Thromboembolic events occurred in 21 patients with aortic valve replacement (1.3% ±0.2%/ pt-yr), in 12 with mitral valve replacement (1.2% ± 0.3% pt-yr), and in seven with mitral and aortic valve replacement (2.1% ± 0.8%), with one case of prosthetic thrombosis in each group; actuarial freedom from thromboembolism at 9 years is 92 % ± 3 % after mitral valve replacement, 91 % ± 3 % after aortic valve replacement, and 74% ± 16% after mitral and aortic valve replacement. Anticoagulant-related hemorrhage was observed in 15 patients after aortic valve replacement (0.9% ± 0.2%/pt-yr), in 9 after mitral valve replacement (0.9% ± 0.3%/pt-yr), and in 6 with mitral and aortic valve replacement (0.9% ± 0.5%/pt-yr); actuarial freedom from this complication at 9 years is 94% ±2% after aortic valve replacement, 91% ±4% after mitral valve replacement, and 68% ± 16% after mitral and aortic valve replacement. Actuarial freedom from reoperation at 9 years is 97% ±2% after mitral and aortic valve replacement, 92% ±4% after mitral valve replacement, and 89% ±3% after aortic valve replacement, with no cases of mechanical fracture. The Sorin valve has shown a satisfactory long-term overall performance, comparable with other mechanical prostheses, and an excellent durability that renders it a reliable heart valve substitute for the mitral and aortic positions. (J Thorac Cardiovasc Surg 1992;103:267—75)" @default.
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• W4321000864 date "1992-02-01" @default.
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• W4321000864 title "Heart valve replacement with the Sorin tilting-disc prosthesis" @default.
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• W4321000864 doi "https://doi.org/10.1016/s0022-5223(19)35027-5" @default.
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