FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321015662> ?p ?o ?g. }

• W4321015662 abstract "In this work, we synthesized lactobionic acid-decorated diselenide-linked polyethylene glycol-doxorubicin conjugate (LA-PEG-SeSe-DOX) and prepared free DOX-loaded LA-PEG-SeSe-DOX(DOX@LA-PEG-SeSe-DOX) nanoparticles for hepatoma-targeted DOX delivery. LA-PEG-SeSe-DOX can self-assemble into nanoparticles in deionized water and DOX@LA-PEG-SeSe-DOX nanoparticles were prepared by loading free DOX into LA-PEG-Se-Se-DOX nanoparticles under sonication. DOX@LA-PEG-SeSe-DOX nanoparticles have high DOX loading content of 31.3%. The dynamic scattering analysis shows that DOX@LA-PEG-SeSe-DOX nanoparticles have small size (hydrodynamic diameter [Formula: see text][Formula: see text]nm), near neutral zeta potential, and excellent colloidal stability. The in vitro drug release study indicates that DOX@LA-PEG-SeSe-DOX nanoparticles exhibit dual redox-responsive drug release characteristics. The cellular uptake study reveals that DOX@LA-PEG-SeSe-DOX nanoparticles can be taken up by hepatoma cells by asialoglycoprotein receptor (ASGPR)-mediated pathway. Finally, DOX@LA-PEG-SeSe-DOX nanoparticles exhibit enhanced cytotoxicity against HepG2 cells as compared to LA-PEG-SeSe-DOX nanoparticles, underlining the significance of releasing free DOX for effective tumor cell proliferation inhibition. This work provides a facile and effective strategy for targeted delivery of DOX to hepatoma cells." @default.
• W4321015662 created "2023-02-17" @default.
• W4321015662 creator A5030222851 @default.
• W4321015662 creator A5030659376 @default.
• W4321015662 creator A5049149230 @default.
• W4321015662 creator A5063472996 @default.
• W4321015662 creator A5074750047 @default.
• W4321015662 date "2023-03-10" @default.
• W4321015662 modified "2023-10-18" @default.
• W4321015662 title "Targeted Delivery of Doxorubicin to Hepatoma Cells by Lactobionic Acid-Decorated Dual Redox-Responsive Polyethylene Glycol-Doxorubicin Nanoparticles" @default.
• W4321015662 cites W2008294808 @default.
• W4321015662 cites W2467793432 @default.
• W4321015662 cites W2545028981 @default.
• W4321015662 cites W2559418009 @default.
• W4321015662 cites W2593778224 @default.
• W4321015662 cites W2594539275 @default.
• W4321015662 cites W2740350862 @default.
• W4321015662 cites W2761496094 @default.
• W4321015662 cites W2797710704 @default.
• W4321015662 cites W2800356358 @default.
• W4321015662 cites W2801418805 @default.
• W4321015662 cites W2807582167 @default.
• W4321015662 cites W2964082237 @default.
• W4321015662 cites W2968917807 @default.
• W4321015662 cites W2981146931 @default.
• W4321015662 cites W2998407485 @default.
• W4321015662 cites W3043498385 @default.
• W4321015662 cites W3091947122 @default.
• W4321015662 cites W3118881956 @default.
• W4321015662 cites W3128668155 @default.
• W4321015662 cites W3134630022 @default.
• W4321015662 cites W3142751162 @default.
• W4321015662 cites W3162924348 @default.
• W4321015662 cites W3165671098 @default.
• W4321015662 cites W4200099034 @default.
• W4321015662 doi "https://doi.org/10.1142/s0219581x23500199" @default.
• W4321015662 hasPublicationYear "2023" @default.
• W4321015662 type Work @default.
• W4321015662 citedByCount "0" @default.
• W4321015662 crossrefType "journal-article" @default.
• W4321015662 hasAuthorship W4321015662A5030222851 @default.
• W4321015662 hasAuthorship W4321015662A5030659376 @default.
• W4321015662 hasAuthorship W4321015662A5049149230 @default.
• W4321015662 hasAuthorship W4321015662A5063472996 @default.
• W4321015662 hasAuthorship W4321015662A5074750047 @default.
• W4321015662 hasConcept C10138342 @default.
• W4321015662 hasConcept C109316439 @default.
• W4321015662 hasConcept C12554922 @default.
• W4321015662 hasConcept C13965031 @default.
• W4321015662 hasConcept C141071460 @default.
• W4321015662 hasConcept C155672457 @default.
• W4321015662 hasConcept C162324750 @default.
• W4321015662 hasConcept C171250308 @default.
• W4321015662 hasConcept C185592680 @default.
• W4321015662 hasConcept C192562407 @default.
• W4321015662 hasConcept C202751555 @default.
• W4321015662 hasConcept C2776694085 @default.
• W4321015662 hasConcept C2776964284 @default.
• W4321015662 hasConcept C2779820397 @default.
• W4321015662 hasConcept C2781303535 @default.
• W4321015662 hasConcept C54400483 @default.
• W4321015662 hasConcept C55493867 @default.
• W4321015662 hasConcept C71924100 @default.
• W4321015662 hasConcept C86181022 @default.
• W4321015662 hasConcept C86803240 @default.
• W4321015662 hasConceptScore W4321015662C10138342 @default.
• W4321015662 hasConceptScore W4321015662C109316439 @default.
• W4321015662 hasConceptScore W4321015662C12554922 @default.
• W4321015662 hasConceptScore W4321015662C13965031 @default.
• W4321015662 hasConceptScore W4321015662C141071460 @default.
• W4321015662 hasConceptScore W4321015662C155672457 @default.
• W4321015662 hasConceptScore W4321015662C162324750 @default.
• W4321015662 hasConceptScore W4321015662C171250308 @default.
• W4321015662 hasConceptScore W4321015662C185592680 @default.
• W4321015662 hasConceptScore W4321015662C192562407 @default.
• W4321015662 hasConceptScore W4321015662C202751555 @default.
• W4321015662 hasConceptScore W4321015662C2776694085 @default.
• W4321015662 hasConceptScore W4321015662C2776964284 @default.
• W4321015662 hasConceptScore W4321015662C2779820397 @default.
• W4321015662 hasConceptScore W4321015662C2781303535 @default.
• W4321015662 hasConceptScore W4321015662C54400483 @default.
• W4321015662 hasConceptScore W4321015662C55493867 @default.
• W4321015662 hasConceptScore W4321015662C71924100 @default.
• W4321015662 hasConceptScore W4321015662C86181022 @default.
• W4321015662 hasConceptScore W4321015662C86803240 @default.
• W4321015662 hasIssue "03" @default.
• W4321015662 hasLocation W43210156621 @default.
• W4321015662 hasOpenAccess W4321015662 @default.
• W4321015662 hasPrimaryLocation W43210156621 @default.
• W4321015662 hasRelatedWork W1979007235 @default.
• W4321015662 hasRelatedWork W1997154110 @default.
• W4321015662 hasRelatedWork W2001407275 @default.
• W4321015662 hasRelatedWork W2046273656 @default.
• W4321015662 hasRelatedWork W2140907237 @default.
• W4321015662 hasRelatedWork W2379733913 @default.
• W4321015662 hasRelatedWork W2467226026 @default.
• W4321015662 hasRelatedWork W2809854728 @default.
• W4321015662 hasRelatedWork W2886620535 @default.
• W4321015662 hasRelatedWork W2999916507 @default.
• W4321015662 hasVolume "22" @default.

• next