FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321019968> ?p ?o ?g. }

• W4321019968 endingPage "252" @default.
• W4321019968 startingPage "240" @default.
• W4321019968 abstract "Technological advancements in phylodynamic modeling coupled with the accessibility of real-time pathogen genetic data are increasingly important for understanding the infectious disease transmission dynamics. In this study, we compare the transmission potentials of North American influenza A(H1N1)pdm09 derived from sequence data to that derived from surveillance data. The impact of the choice of tree-priors, informative epidemiological priors, and evolutionary parameters on the transmission potential estimation is evaluated. North American Influenza A(H1N1)pdm09 hemagglutinin (HA) gene sequences are analyzed using the coalescent and birth-death tree prior models to estimate the basic reproduction number (R0). Epidemiological priors gathered from published literature are used to simulate the birth-death skyline models. Path-sampling marginal likelihood estimation is conducted to assess model fit. A bibliographic search to gather surveillance-based R0 values were consistently lower (mean ≤ 1.2) when estimated by coalescent models than by the birth-death models with informative priors on the duration of infectiousness (mean ≥ 1.3 to ≤2.88 days). The user-defined informative priors for use in the birth-death model shift the directionality of epidemiological and evolutionary parameters compared to non-informative estimates. While there was no certain impact of clock rate and tree height on the R0 estimation, an opposite relationship was observed between coalescent and birth-death tree priors. There was no significant difference (p = 0.46) between the birth-death model and surveillance R0 estimates. This study concludes that tree-prior methodological differences may have a substantial impact on the transmission potential estimation as well as the evolutionary parameters. The study also reports a consensus between the sequence-based R0 estimation and surveillance-based R0 estimates. Altogether, these outcomes shed light on the potential role of phylodynamic modeling to augment existing surveillance and epidemiological activities to better assess and respond to emerging infectious diseases." @default.
• W4321019968 created "2023-02-17" @default.
• W4321019968 creator A5007833843 @default.
• W4321019968 creator A5012990145 @default.
• W4321019968 creator A5020439458 @default.
• W4321019968 creator A5028683444 @default.
• W4321019968 creator A5029728611 @default.
• W4321019968 creator A5053427557 @default.
• W4321019968 creator A5053513823 @default.
• W4321019968 creator A5061939751 @default.
• W4321019968 creator A5070112575 @default.
• W4321019968 date "2023-03-01" @default.
• W4321019968 modified "2023-09-30" @default.
• W4321019968 title "Comparing the transmission potential from sequence and surveillance data of 2009 North American influenza pandemic waves" @default.
• W4321019968 cites W1537086245 @default.
• W4321019968 cites W1563370435 @default.
• W4321019968 cites W1760888244 @default.
• W4321019968 cites W1970129213 @default.
• W4321019968 cites W1973194618 @default.
• W4321019968 cites W1973969634 @default.
• W4321019968 cites W1988533731 @default.
• W4321019968 cites W1999011326 @default.
• W4321019968 cites W2002740941 @default.
• W4321019968 cites W2004506270 @default.
• W4321019968 cites W2004561367 @default.
• W4321019968 cites W2018095486 @default.
• W4321019968 cites W2026062398 @default.
• W4321019968 cites W2035692177 @default.
• W4321019968 cites W2041572706 @default.
• W4321019968 cites W2042911213 @default.
• W4321019968 cites W2068353535 @default.
• W4321019968 cites W2069947547 @default.
• W4321019968 cites W2073145072 @default.
• W4321019968 cites W2077177427 @default.
• W4321019968 cites W2087998303 @default.
• W4321019968 cites W2098062910 @default.
• W4321019968 cites W2098998255 @default.
• W4321019968 cites W2110835349 @default.
• W4321019968 cites W2112164121 @default.
• W4321019968 cites W2117002055 @default.
• W4321019968 cites W2120939112 @default.
• W4321019968 cites W2122980269 @default.
• W4321019968 cites W2130878567 @default.
• W4321019968 cites W2132926880 @default.
• W4321019968 cites W2134792562 @default.
• W4321019968 cites W2137488844 @default.
• W4321019968 cites W2137553994 @default.
• W4321019968 cites W2140425076 @default.
• W4321019968 cites W2141052558 @default.
• W4321019968 cites W2141478803 @default.
• W4321019968 cites W2141921564 @default.
• W4321019968 cites W2142773663 @default.
• W4321019968 cites W2144485968 @default.
• W4321019968 cites W2150933014 @default.
• W4321019968 cites W2153708508 @default.
• W4321019968 cites W2153749443 @default.
• W4321019968 cites W2155528202 @default.
• W4321019968 cites W2157725602 @default.
• W4321019968 cites W2160253520 @default.
• W4321019968 cites W2162129743 @default.
• W4321019968 cites W2162311941 @default.
• W4321019968 cites W2165012312 @default.
• W4321019968 cites W2171647573 @default.
• W4321019968 cites W2180795200 @default.
• W4321019968 cites W2266769980 @default.
• W4321019968 cites W2322358787 @default.
• W4321019968 cites W2409392110 @default.
• W4321019968 cites W2516104505 @default.
• W4321019968 cites W2588115077 @default.
• W4321019968 cites W2605343262 @default.
• W4321019968 cites W2726578143 @default.
• W4321019968 cites W2749686571 @default.
• W4321019968 cites W2761578221 @default.
• W4321019968 cites W2775569101 @default.
• W4321019968 cites W2793085393 @default.
• W4321019968 cites W2795440218 @default.
• W4321019968 cites W2807308836 @default.
• W4321019968 cites W2910006651 @default.
• W4321019968 cites W2949322686 @default.
• W4321019968 cites W2952384398 @default.
• W4321019968 cites W2997069256 @default.
• W4321019968 cites W3101335933 @default.
• W4321019968 cites W3104691176 @default.
• W4321019968 cites W3158148925 @default.
• W4321019968 cites W4211177544 @default.
• W4321019968 cites W4224216303 @default.
• W4321019968 doi "https://doi.org/10.1016/j.idm.2023.02.003" @default.
• W4321019968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36844759" @default.
• W4321019968 hasPublicationYear "2023" @default.
• W4321019968 type Work @default.
• W4321019968 citedByCount "0" @default.
• W4321019968 crossrefType "journal-article" @default.
• W4321019968 hasAuthorship W4321019968A5007833843 @default.
• W4321019968 hasAuthorship W4321019968A5012990145 @default.
• W4321019968 hasAuthorship W4321019968A5020439458 @default.
• W4321019968 hasAuthorship W4321019968A5028683444 @default.
• W4321019968 hasAuthorship W4321019968A5029728611 @default.
• W4321019968 hasAuthorship W4321019968A5053427557 @default.

• next