FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321168233> ?p ?o ?g. }

• W4321168233 endingPage "88" @default.
• W4321168233 startingPage "75" @default.
• W4321168233 abstract "The high mortality of coronavirus disease 2019 is related to poor antigen presentation and lymphopenia. Cytomegalovirus and the herpes family encode a series of major histocompatibility complex (MHC)-like molecules required for targeted immune responses to achieve immune escape. In this present study, domain search results showed that many proteins of the severe acute respiratory syndrome coronavirus 2 virus had MHC-like domains, which were similar to decoys for the human immune system. MHC-like structures could bind to MHC receptors of immune cells (such as CD4 + T-cell, CD8 + T-cell, and natural killer-cell), interfering with antigen presentation. Then the oxygen free radicals generated by E protein destroyed immune cells after MHC-like of S protein could bind to them. Mutations in the MHC-like region of the viral proteins such as S promoted weaker immune resistance and more robust transmission. S 127–194 were the primary reason for the robust transmission of delta variants. The S 144–162 regulated the formation of S trimer. The mutations of RdRP: G671S and N: D63G of delta variant caused high viral load. S 62–80 of alpha, beta, lambda variants were the important factor for fast-spreading. S 616–676 and 1014–1114 were causes of high mortality for gamma variants infections. These sites were in the MHC-like structure regions." @default.
• W4321168233 created "2023-02-18" @default.
• W4321168233 creator A5038452401 @default.
• W4321168233 creator A5041366828 @default.
• W4321168233 date "2023-02-20" @default.
• W4321168233 modified "2023-09-24" @default.
• W4321168233 title "COVID-19: Attacks Immune Cells and Interferences With Antigen Presentation Through MHC-Like Decoy System" @default.
• W4321168233 cites W1844798933 @default.
• W4321168233 cites W1963542053 @default.
• W4321168233 cites W1966280572 @default.
• W4321168233 cites W1969830531 @default.
• W4321168233 cites W1972434619 @default.
• W4321168233 cites W1975388230 @default.
• W4321168233 cites W1977787535 @default.
• W4321168233 cites W1978037344 @default.
• W4321168233 cites W1991780615 @default.
• W4321168233 cites W1992849411 @default.
• W4321168233 cites W1993740185 @default.
• W4321168233 cites W2005765588 @default.
• W4321168233 cites W2006987558 @default.
• W4321168233 cites W2008296972 @default.
• W4321168233 cites W2009478166 @default.
• W4321168233 cites W2039638023 @default.
• W4321168233 cites W2055771235 @default.
• W4321168233 cites W2064890413 @default.
• W4321168233 cites W2108367007 @default.
• W4321168233 cites W2125024220 @default.
• W4321168233 cites W2132913569 @default.
• W4321168233 cites W3001118548 @default.
• W4321168233 cites W3006116465 @default.
• W4321168233 cites W3007940623 @default.
• W4321168233 cites W3017304088 @default.
• W4321168233 cites W3036850492 @default.
• W4321168233 cites W3080428800 @default.
• W4321168233 cites W3082404514 @default.
• W4321168233 cites W3110730557 @default.
• W4321168233 cites W3113050158 @default.
• W4321168233 cites W3113745946 @default.
• W4321168233 cites W3121319444 @default.
• W4321168233 cites W3125078121 @default.
• W4321168233 cites W3125116188 @default.
• W4321168233 cites W3133280392 @default.
• W4321168233 cites W3135383916 @default.
• W4321168233 cites W3135626597 @default.
• W4321168233 cites W3136437538 @default.
• W4321168233 cites W3136616180 @default.
• W4321168233 cites W3139036184 @default.
• W4321168233 cites W3152739191 @default.
• W4321168233 cites W3156343712 @default.
• W4321168233 cites W3163313401 @default.
• W4321168233 cites W3175562186 @default.
• W4321168233 cites W3210962932 @default.
• W4321168233 cites W3216478751 @default.
• W4321168233 doi "https://doi.org/10.1097/cji.0000000000000455" @default.
• W4321168233 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36799912" @default.
• W4321168233 hasPublicationYear "2023" @default.
• W4321168233 type Work @default.
• W4321168233 citedByCount "1" @default.
• W4321168233 countsByYear W43211682332023 @default.
• W4321168233 crossrefType "journal-article" @default.
• W4321168233 hasAuthorship W4321168233A5038452401 @default.
• W4321168233 hasAuthorship W4321168233A5041366828 @default.
• W4321168233 hasBestOaLocation W43211682332 @default.
• W4321168233 hasConcept C147483822 @default.
• W4321168233 hasConcept C159047783 @default.
• W4321168233 hasConcept C167672396 @default.
• W4321168233 hasConcept C170627219 @default.
• W4321168233 hasConcept C203014093 @default.
• W4321168233 hasConcept C207936829 @default.
• W4321168233 hasConcept C2776090121 @default.
• W4321168233 hasConcept C83464605 @default.
• W4321168233 hasConcept C86803240 @default.
• W4321168233 hasConcept C8891405 @default.
• W4321168233 hasConceptScore W4321168233C147483822 @default.
• W4321168233 hasConceptScore W4321168233C159047783 @default.
• W4321168233 hasConceptScore W4321168233C167672396 @default.
• W4321168233 hasConceptScore W4321168233C170627219 @default.
• W4321168233 hasConceptScore W4321168233C203014093 @default.
• W4321168233 hasConceptScore W4321168233C207936829 @default.
• W4321168233 hasConceptScore W4321168233C2776090121 @default.
• W4321168233 hasConceptScore W4321168233C83464605 @default.
• W4321168233 hasConceptScore W4321168233C86803240 @default.
• W4321168233 hasConceptScore W4321168233C8891405 @default.
• W4321168233 hasIssue "3" @default.
• W4321168233 hasLocation W43211682331 @default.
• W4321168233 hasLocation W43211682332 @default.
• W4321168233 hasLocation W43211682333 @default.
• W4321168233 hasLocation W43211682334 @default.
• W4321168233 hasOpenAccess W4321168233 @default.
• W4321168233 hasPrimaryLocation W43211682331 @default.
• W4321168233 hasRelatedWork W2000941383 @default.
• W4321168233 hasRelatedWork W2023967363 @default.
• W4321168233 hasRelatedWork W2065430316 @default.
• W4321168233 hasRelatedWork W2065558906 @default.
• W4321168233 hasRelatedWork W2109577448 @default.
• W4321168233 hasRelatedWork W2127924868 @default.
• W4321168233 hasRelatedWork W2147210428 @default.
• W4321168233 hasRelatedWork W2150467115 @default.

• next