Matches in SemOpenAlex for { <https://semopenalex.org/work/W4321368045> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W4321368045 endingPage "S18" @default.
- W4321368045 startingPage "S18" @default.
- W4321368045 abstract "Regression of atherosclerosis is a key aspect of preventing further coronary artery disease and understanding which cell type forms smooth muscle cells in atherosclerotic fibrous caps will aid in reducing CAD. Atherogenesis is a complex interplay of cells migrating and proliferating into the vascular wall. CD34 positive hemapoetic stem cells are believed to not transform into vascular smooth muscle cells (SMC). The current study hypothesised that there would be no evidence for CD34+/α SMC actin+ cells in atherosclerotic coronary arteries. Aims: To identify CD34+/α actin positive cells in the fibrous cap and wall of atherosclerotic plaques in the coronary artery. Methods: Male New Zealand White rabbits were fed a diet containing 0.5% cholesterol and 1% methionine for 4 weeks, then 9 weeks of normal diet to induce regression. Immunohistochemistry was used to detect CD34+ haematopoietic progenitor cells and α SMC actin. Results: In the fibrous cap, the majority of cells were CD34−/α SMC actin+ spindle shaped cells. However very rare populations of CD34+/α SMC actin+ and CD34+/α SMC actin− cells were also present but these cells were not spindle shaped. Conclusion: Our study found that CD34+/α SMC actin− spindle shaped cells were absent from the fibrous cap. Moreover, the predominant cell population were the vascular smooth muscle cells (CD34−/α SMC actin+) but (CD34+/α SMC actin+) cells were also present. This model could be used to understand the role of each SMC population subtype to hasten atherosclerotic regression in the coronary artery." @default.
- W4321368045 created "2023-02-21" @default.
- W4321368045 creator A5007388912 @default.
- W4321368045 creator A5008431285 @default.
- W4321368045 creator A5015734199 @default.
- W4321368045 creator A5027785173 @default.
- W4321368045 creator A5050821228 @default.
- W4321368045 creator A5062299458 @default.
- W4321368045 creator A5067619716 @default.
- W4321368045 creator A5087094615 @default.
- W4321368045 date "2023-02-01" @default.
- W4321368045 modified "2023-09-26" @default.
- W4321368045 title "CRT-100.7 A Contemporary Assessment of Major Bleeding Complications in Patients Undergoing Percutaneous Coronary Intervention: Which Factors Really Count?" @default.
- W4321368045 doi "https://doi.org/10.1016/j.jcin.2023.01.074" @default.
- W4321368045 hasPublicationYear "2023" @default.
- W4321368045 type Work @default.
- W4321368045 citedByCount "0" @default.
- W4321368045 crossrefType "journal-article" @default.
- W4321368045 hasAuthorship W4321368045A5007388912 @default.
- W4321368045 hasAuthorship W4321368045A5008431285 @default.
- W4321368045 hasAuthorship W4321368045A5015734199 @default.
- W4321368045 hasAuthorship W4321368045A5027785173 @default.
- W4321368045 hasAuthorship W4321368045A5050821228 @default.
- W4321368045 hasAuthorship W4321368045A5062299458 @default.
- W4321368045 hasAuthorship W4321368045A5067619716 @default.
- W4321368045 hasAuthorship W4321368045A5087094615 @default.
- W4321368045 hasConcept C10205521 @default.
- W4321368045 hasConcept C125705527 @default.
- W4321368045 hasConcept C126322002 @default.
- W4321368045 hasConcept C142724271 @default.
- W4321368045 hasConcept C164705383 @default.
- W4321368045 hasConcept C201750760 @default.
- W4321368045 hasConcept C2776820930 @default.
- W4321368045 hasConcept C2778213512 @default.
- W4321368045 hasConcept C2779179121 @default.
- W4321368045 hasConcept C2779395532 @default.
- W4321368045 hasConcept C28328180 @default.
- W4321368045 hasConcept C2908647359 @default.
- W4321368045 hasConcept C2992686903 @default.
- W4321368045 hasConcept C71924100 @default.
- W4321368045 hasConcept C86803240 @default.
- W4321368045 hasConcept C95444343 @default.
- W4321368045 hasConcept C99454951 @default.
- W4321368045 hasConceptScore W4321368045C10205521 @default.
- W4321368045 hasConceptScore W4321368045C125705527 @default.
- W4321368045 hasConceptScore W4321368045C126322002 @default.
- W4321368045 hasConceptScore W4321368045C142724271 @default.
- W4321368045 hasConceptScore W4321368045C164705383 @default.
- W4321368045 hasConceptScore W4321368045C201750760 @default.
- W4321368045 hasConceptScore W4321368045C2776820930 @default.
- W4321368045 hasConceptScore W4321368045C2778213512 @default.
- W4321368045 hasConceptScore W4321368045C2779179121 @default.
- W4321368045 hasConceptScore W4321368045C2779395532 @default.
- W4321368045 hasConceptScore W4321368045C28328180 @default.
- W4321368045 hasConceptScore W4321368045C2908647359 @default.
- W4321368045 hasConceptScore W4321368045C2992686903 @default.
- W4321368045 hasConceptScore W4321368045C71924100 @default.
- W4321368045 hasConceptScore W4321368045C86803240 @default.
- W4321368045 hasConceptScore W4321368045C95444343 @default.
- W4321368045 hasConceptScore W4321368045C99454951 @default.
- W4321368045 hasIssue "4" @default.
- W4321368045 hasLocation W43213680451 @default.
- W4321368045 hasOpenAccess W4321368045 @default.
- W4321368045 hasPrimaryLocation W43213680451 @default.
- W4321368045 hasRelatedWork W1998228373 @default.
- W4321368045 hasRelatedWork W2101046603 @default.
- W4321368045 hasRelatedWork W2135793203 @default.
- W4321368045 hasRelatedWork W2285286601 @default.
- W4321368045 hasRelatedWork W2300366807 @default.
- W4321368045 hasRelatedWork W2801524442 @default.
- W4321368045 hasRelatedWork W3113925325 @default.
- W4321368045 hasRelatedWork W3176144001 @default.
- W4321368045 hasRelatedWork W3213450778 @default.
- W4321368045 hasRelatedWork W4224310268 @default.
- W4321368045 hasVolume "16" @default.
- W4321368045 isParatext "false" @default.
- W4321368045 isRetracted "false" @default.
- W4321368045 workType "article" @default.